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Large language models (LLMs) show promise for healthcare question answering, but clinical use is limited by weak verification, insufficient evidence grounding, and unreliable confidence signalling. We propose a multi-agent medical QA…

Computation and Language · Computer Science 2026-02-17 Naeimeh Nourmohammadi , Md Meem Hossain , The Anh Han , Safina Showkat Ara , Zia Ush Shamszaman

Inspired by the chemotaxis interaction of living cells, we have developed an agent-based approach for self-organizing shape formation. Since all our simulations begin with a different uniform random configuration and our agents move…

Multiagent Systems · Computer Science 2018-03-13 Sean Grimes , Linge Bai , Andrew W. E. McDonald , David E. Breen

Many cellular processes involve information processing and decision making. We can probe these processes at increasing molecular detail. The analysis of heterogeneous data remains a challenge that requires new ways of thinking about cells…

Cell Behavior · Quantitative Biology 2024-12-03 Lucy Ham , Taylor E. Woodford , Megan A. Coomer , Michael P. H. Stumpf

Individualized treatment rules (ITR) can improve health outcomes by recognizing that patients may respond differently to treatment and assigning therapy with the most desirable predicted outcome for each individual. Flexible and efficient…

Methodology · Statistics 2017-09-25 Brent R. Logan , Rodney Sparapani , Robert E. McCulloch , Purushottam W. Laud

In this paper, we study the computation of the rate-distortion-perception function (RDPF) for discrete memoryless sources subject to a single-letter average distortion constraint and a perception constraint that belongs to the family of…

Information Theory · Computer Science 2023-05-09 Giuseppe Serra , Photios A. Stavrou , Marios Kountouris

Despite being recognized as neurobiologically plausible, active inference faces difficulties when employed to simulate intelligent behaviour in complex environments due to its computational cost and the difficulty of specifying an…

Machine Learning · Computer Science 2024-06-12 Aswin Paul , Noor Sajid , Lancelot Da Costa , Adeel Razi

Cellular bioelectricity describes the biological phenomenon in which cells in living tissue generate and maintain patterns of voltage gradients induced by differing concentrations of charged ions. A growing body of research suggests that…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-09-27 Seth Gilbert , James Maguire , Calvin Newport

Large Language Models (LLMs) have shown remarkable capabilities in natural language tasks requiring complex reasoning, yet their application in agentic, multi-step reasoning within interactive environments remains a difficult challenge.…

Artificial Intelligence · Computer Science 2024-08-15 Pranav Putta , Edmund Mills , Naman Garg , Sumeet Motwani , Chelsea Finn , Divyansh Garg , Rafael Rafailov

Biological cells are able to adapt their behaviour in response to environmental cues. Durotaxis is a phenomenon in which cells adjust their migration depending on the mechanical properties of a surrounding substrate. Although durotaxis has…

Biological Physics · Physics 2026-05-11 Sohei Nakamura , Mitsusuke Tarama

Accurate gradient sensing is crucial for efficient chemotaxis in noisy environments, but the relationship between cell shape deformations and sensing accuracy is not well understood. Using a theoretical framework based on maximum likelihood…

Biological Physics · Physics 2025-03-07 Daiqiu Mou , Yuansheng Cao

Agents that learn to select optimal actions represent a prominent focus of the sequential decision-making literature. In the face of a complex environment or constraints on time and resources, however, aiming to synthesize such an optimal…

Machine Learning · Computer Science 2021-06-23 Dilip Arumugam , Benjamin Van Roy

Long-horizon language agents must operate under limited runtime memory, yet existing memory mechanisms often organize experience around descriptive criteria such as relevance, salience, or summary quality. For an agent, however, memory is…

Artificial Intelligence · Computer Science 2026-05-12 Mingxi Zou , Zhihan Guo , Langzhang Liang , Zhuo Wang , Qifan Wang , Qingsong Wen , Irwin King , Lizhen Qu , Zenglin Xu

We present an anytime algorithm which computes policies for decision problems represented as multi-stage influence diagrams. Our algorithm constructs policies incrementally, starting from a policy which makes no use of the available…

Artificial Intelligence · Computer Science 2013-02-01 Michael C. Horsch , David L. Poole

Deep Research Agents (DRAs) are promising agentic systems that gather and synthesize information to support research across domains such as financial decision-making, medical analysis, and scientific discovery. Despite recent improvements…

Artificial Intelligence · Computer Science 2026-02-27 Haotian Zhai , Elias Stengel-Eskin , Pratik Patil , Liu Leqi

We study how to accelerate Bayesian optimization (BO) on a target task by transferring historical knowledge from related source tasks. Existing work on BO with knowledge transfer either lacks theoretical guarantees or achieves the same…

Machine Learning · Statistics 2026-04-29 Haitao Lin , Boxin Zhao , Mladen Kolar , Chong Liu

Biological brains are inherently limited in their capacity to process and store information, but are nevertheless capable of solving complex tasks with apparent ease. Intelligent behavior is related to these limitations, since resource…

Neurons and Cognition · Quantitative Biology 2020-11-16 Nisheet Patel , Luigi Acerbi , Alexandre Pouget

Neural Cellular Automata (NCA) represent a powerful framework for modeling biological self-organization, extending classical rule-based systems with trainable, differentiable (or evolvable) update rules that capture the adaptive…

Artificial Intelligence · Computer Science 2025-09-16 Benedikt Hartl , Michael Levin , Léo Pio-Lopez

In distributed processing, agents generally collect data generated by the same underlying unknown model (represented by a vector of parameters) and then solve an estimation or inference task cooperatively. In this paper, we consider the…

Information Theory · Computer Science 2015-06-16 Sheng-Yuan Tu , Ali H. Sayed

We study the effect of imperfect memory on decision making in the context of a stochastic sequential action-reward problem. An agent chooses a sequence of actions which generate discrete rewards at different rates. She is allowed to make…

Probability · Mathematics 2019-09-20 Kuang Xu , Se-Young Yun

Cells rely on the ability to sense and respond to small spatial differences in chemoattractant concentrations for survival. There is growing evidence that this is accomplished by setting the signaling system near the threshold for…

Cell Behavior · Quantitative Biology 2022-05-19 Debojyoti Biswas , Parijat Banerjee , Pablo A. Iglesias