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The increasing importance of Computational Science and Engineering has highlighted the need for high-quality scientific software. However, research software development is often hindered by limited funding, time, staffing, and technical…

Software Engineering · Computer Science 2025-03-10 Armin Ariamajd , Raquel López-Ríos de Castro , Andrea Volkamer

Protein sequence analysis underpins research in biophysics, computational biology, and bioinformatics. We introduce BEER, a crossplatform graphical interface that accepts FASTA or Protein Data Bank (PDB) files, or manual sequence entry, and…

Biomolecules · Quantitative Biology 2025-04-30 Saumyak Mukherjee

PaPy, which stands for parallel pipelines in Python, is a highly flexible framework that enables the construction of robust, scalable workflows for either generating or processing voluminous datasets. A workflow is created from user-written…

Programming Languages · Computer Science 2014-07-17 Marcin Cieslik , Cameron Mura

COFFEE (ConFormal Field Equation Evolver) is a Python package primarily developed to numerically evolve systems of partial differential equations over time using the method of lines. It includes a variety of time integrators and finite…

Mathematical Software · Computer Science 2023-03-27 Georgios Doulis , Jörg Frauendiener , Chris Stevens , Ben Whale

`scores` is a Python package containing mathematical functions for the verification, evaluation and optimisation of forecasts, predictions or models. It supports labelled n-dimensional (multidimensional) data, which is used in many…

Objectives: Despite the recent adoption of large language models (LLMs) for biomedical information extraction, challenges in prompt engineering and algorithms persist, with no dedicated software available. To address this, we developed…

Machine Learning · Computer Science 2025-04-02 Enshuo Hsu , Kirk Roberts

Multiple software packages currently exist for the computation of bulk topological invariants in both idealized tight-binding models and realistic Wannier tight-binding models derived from density functional theory. Currently, only one…

Materials Science · Physics 2024-06-14 Alexander C. Tyner

In this work, we present scikit-fingerprints, a Python package for computation of molecular fingerprints for applications in chemoinformatics. Our library offers an industry-standard scikit-learn interface, allowing intuitive usage and easy…

Software Engineering · Computer Science 2025-08-12 Jakub Adamczyk , Piotr Ludynia

Machine-learning datasets are typically characterized by measuring their size and class balance. However, there exists a richer and potentially more useful set of measures, termed S-entropy (similarity-sensitive entropy), that incorporate…

Optimal Causation Entropy (oCSE) is a robust causal network modeling technique that reveals causal networks from dynamical systems and coupled oscillators, distinguishing direct from indirect paths. CausationEntropy is a Python package that…

Machine Learning · Computer Science 2026-01-21 Kevin Slote , Jeremie Fish , Erik Bollt

Molecular simulations are an important tool for research in physics, chemistry, and biology. The capabilities of simulations can be greatly expanded by providing access to advanced sampling methods and techniques that permit calculation of…

In recent years, deep generative models have attracted increasing interest due to their capacity to model complex distributions. Among those models, variational autoencoders have gained popularity as they have proven both to be…

Machine Learning · Computer Science 2023-07-21 Clément Chadebec , Louis J. Vincent , Stéphanie Allassonnière

NIFTY, "Numerical Information Field Theory", is a software package designed to enable the development of signal inference algorithms that operate regardless of the underlying spatial grid and its resolution. Its object-oriented framework is…

Instrumentation and Methods for Astrophysics · Physics 2013-06-06 Marco Selig , Michael R. Bell , Henrik Junklewitz , Niels Oppermann , Martin Reinecke , Maksim Greiner , Carlos Pachajoa , Torsten A. Enßlin

Recent developments in path integral methodology have significantly reduced the computational expense of including quantum mechanical effects in the nuclear motion in ab initio molecular dynamics simulations. However, the implementation of…

Computational Physics · Physics 2014-02-06 Michele Ceriotti , Joshua More , David E. Manolopoulos

STACIE (STable AutoCorrelation Integral Estimator) is a novel algorithm and Python package that delivers robust, uncertainty-aware estimates of autocorrelation integrals from time-correlated data. While its primary application is deriving…

Computational Physics · Physics 2025-09-24 Gözdenur Toraman , Dieter Fauconnier , Toon Verstraelen

Converting peptide sequences into useful representations for downstream analysis is a common step in computational modeling and cheminformatics. Furthermore, peptide drugs (e.g., Semaglutide, Degarelix) often take advantage of the diverse…

Biomolecules · Quantitative Biology 2025-05-05 Aaron L. Feller , Claus O. Wilke

We develop a Python-based open-source package to analyze the results stemming from ab initio molecular-dynamics simulations of fluids. The package is best suited for applications on natural systems, like silicate and oxide melts,…

The cost of combustion simulations is often dominated by the evaluation of net production rates of chemical species and mixture thermodynamics (thermochemistry). Execution on computing accelerators (XPUs) like graphic processing units…

Ordinary Differential Equations (ODE) are used throughout science where the capture of rates of change in states is sought. While both pieces of commercial and open software exist to study such systems, their efficient and accurate usage…

Mathematical Software · Computer Science 2018-03-20 Edwin Tye , Tom Finnie , Ian Hall , Steve Leach

Many physical processes can be expressed through partial differential equations (PDEs). Real-world measurements of such processes are often collected at irregularly distributed points in space, which can be effectively represented as…

Machine Learning · Computer Science 2025-07-16 Jost Arndt , Utku Isil , Michael Detzel , Wojciech Samek , Jackie Ma