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The diagnosis of prostate cancer is challenging due to the heterogeneity of its presentations, leading to the over diagnosis and treatment of non-clinically important disease. Accurate diagnosis can directly benefit a patient's quality of…

Multiparametric magnetic resonance imaging (mp-MRI) has shown excellent results in the detection of prostate cancer (PCa). However, characterizing prostate lesions aggressiveness in mp-MRI sequences is impossible in clinical practice, and…

Image and Video Processing · Electrical Eng. & Systems 2022-11-28 Audrey Duran , Gaspard Dussert , Olivier Rouvière , Tristan Jaouen , Pierre-Marc Jodoin , Carole Lartizien

The rapid proliferation of open-source medical foundation models (FMs) raises a practical question: how well do their pre-trained representations transfer to clinically relevant but data-scarce classification tasks? Particularly in CT-based…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Hartmut Häntze , Sarah de Boer , Myrthe Buser , Alessa Hering , Bram van Ginneken , Mathias Prokop , Jawed Nawabi , Sebastian Ziegelmayer , Lisa Adams , Keno Bressem

The recent introduction of synthetic correlated diffusion (CDI$^s$) imaging has demonstrated significant potential in the realm of clinical decision support for prostate cancer (PCa). CDI$^s$ is a new form of magnetic resonance imaging…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Hayden Gunraj , Chi-en Amy Tai , Alexander Wong

The domain discrepancy existed between medical images acquired in different situations renders a major hurdle in deploying pre-trained medical image segmentation models for clinical use. Since it is less possible to distribute training data…

Computer Vision and Pattern Recognition · Computer Science 2022-11-22 Shishuai Hu , Zehui Liao , Yong Xia

Artificial intelligence systems show promise to aid in the di- agnostic pathway of prostate cancer (PC), by supporting radiologists in interpreting magnetic resonance images (MRI) of the prostate. Most MRI-based systems are designed to…

Image and Video Processing · Electrical Eng. & Systems 2025-02-18 Erlend Sortland Rolfsnes , Philip Thangngat , Trygve Eftestøl , Tobias Nordström , Fredrik Jäderling , Martin Eklund , Alvaro Fernandez-Quilez

Wearable medical sensors (WMSs) are revolutionizing smart healthcare by enabling continuous, real-time monitoring of user physiological signals, especially in the field of consumer healthcare. The integration of WMSs and modern machine…

Machine Learning · Computer Science 2024-10-22 Chia-Hao Li , Niraj K. Jha

Cardiotoxicity related to cancer therapies has become a serious issue, diminishing cancer treatment outcomes and quality of life. Early detection of cancer patients at risk for cardiotoxicity before cardiotoxic treatments and providing…

Quantitative Methods · Quantitative Biology 2020-05-21 Xi Yang , Yan Gong , Nida Waheed , Keith March , Jiang Bian , William R. Hogan , Yonghui Wu

Background: Tumour budding is an independent predictor of metastasis and prognosis in colorectal cancer and is a vital part of the pathology specification report. In a conventional pathological section observation process, pathologists have…

Medical Physics · Physics 2025-03-21 Yiyan Su , Ruiqing Sun , Yajing Wang , Yanfeng xi , Shaohui Zhang

Deep neural networks have introduced significant advancements in the field of machine learning-based analysis of digital pathology images including prostate tissue images. With the help of transfer learning, classification and segmentation…

The success of precision medicine requires computational models that can effectively process and interpret diverse physiological signals across heterogeneous patient populations. While foundation models have demonstrated remarkable transfer…

Machine Learning · Computer Science 2024-12-05 Matthias Christenson , Cove Geary , Brian Locke , Pranav Koirala , Warren Woodrich Pettine

Recent advances in cancer research largely rely on new developments in microscopic or molecular profiling techniques offering high level of detail with respect to either spatial or molecular features, but usually not both. Here, we present…

Background: The reproducibility of machine-learning models in prostate cancer detection across different MRI vendors remains a significant challenge. Methods: This study investigates Support Vector Machines (SVM) and Random Forest (RF)…

Transformer-based foundation models (FMs) have recently demonstrated remarkable performance in medical image segmentation. However, scaling these models is challenging due to the limited size of medical image datasets within isolated…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 Yumin Zhang , Yan Gao , Haoran Duan , Hanqing Guo , Tejal Shah , Rajiv Ranjan , Bo Wei

Prostate cancer (PCa) poses a significant threat to men's health, with early diagnosis being crucial for improving prognosis and reducing mortality rates. Transrectal ultrasound (TRUS) plays a vital role in the diagnosis and image-guided…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Haiqiao Wang , Hong Wu , Zhuoyuan Wang , Peiyan Yue , Dong Ni , Pheng-Ann Heng , Yi Wang

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

Objective: Survival rate of oral squamous cell carcinoma (OSCC) patients is very poor and can be improved using highly sensitive, specific and accurate techniques. Autofluorescence and fluorescence techniques are very sensitive and useful…

Motivation: Driver (epi)genomic alterations underlie the positive selection of cancer subpopulations, which promotes drug resistance and relapse. Even though substantial heterogeneity is witnessed in most cancer types, mutation accumulation…

To our knowledge, all deep computer-aided detection and diagnosis (CAD) systems for prostate cancer (PCa) detection consider bi-parametric magnetic resonance imaging (bp-MRI) only, including T2w and ADC sequences while excluding the 4D…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Audrey Duran , Gaspard Dussert , Carole Lartizien

Foundation models pretrained on large-scale histopathology data have found great success in various fields of computational pathology, but their impact on regressive biomarker prediction remains underexplored. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Alexander Blezinger , Wolfgang Nejdl , Ming Tang