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Purpose: Prenatal ultrasound is a key tool in evaluating fetal structural development and detecting abnormalities, contributing to reduced perinatal complications and improved neonatal survival. Accurate identification of standard fetal…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Shengjun Zhu , Siyu Liu , Runqing Xiong , Liping Zheng , Duo Ma , Rongshang Chen , Jiaxin Cai

Purpose: Non-invasive grading of prostate cancer (PCa) from micro-ultrasound (micro-US) could expedite triage and guide biopsies toward the most aggressive regions, yet current models struggle to infer tissue micro-structure at coarse…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Emma Willis , Tarek Elghareb , Paul F. R. Wilson , Minh Nguyen Nhat To , Mohammad Mahdi Abootorabi , Amoon Jamzad , Brian Wodlinger , Parvin Mousavi , Purang Abolmaesumi

Survival analysis plays a vital role in making clinical decisions. However, the models currently in use are often difficult to interpret, which reduces their usefulness in clinical settings. Prototype learning presents a potential solution,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Shuo Jiang , Zhuwen Chen , Liaoman Xu , Yanming Zhu , Changmiao Wang , Jiong Zhang , Feiwei Qin , Yifei Chen , Zhu Zhu

Foundation models (FMs) have demonstrated strong transferability across medical imaging tasks, yet their clinical utility depends critically on how pretrained representations are adapted to domain-specific data, supervision regimes, and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Karma Phuntsho , Abdullah , Kyungmi Lee , Ickjai Lee , Euijoon Ahn

The role of artificial intelligence (AI) in pathology has evolved from aiding diagnostics to uncovering predictive morphological patterns in whole slide images (WSIs). Recently, foundation models (FMs) leveraging self-supervised…

This article discusses the opportunities, applications and future directions of large-scale pre-trained models, i.e., foundation models, for analyzing medical images. Medical foundation models have immense potential in solving a wide range…

Image and Video Processing · Electrical Eng. & Systems 2023-11-23 Shaoting Zhang , Dimitris Metaxas

Foundation models (FMs) are rapidly reshaping medical imaging, shifting the field from narrowly trained, task-specific networks toward large, general-purpose models that can be adapted across modalities, anatomies, and clinical tasks. In…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Chuang Niu , Pengwei Wu , Bruno De Man , Ge Wang

Ultrasound is widely used in obstetric care due to its safety, accessibility, and real-time imaging. However, interpretation remains operator-dependent and susceptible to noise and artifacts. Deep learning models have shown strong…

Image and Video Processing · Electrical Eng. & Systems 2026-05-28 Leya Barrientos , Yuexi Du , Nicha C. Dvornek

Breast cancer is the most common cancer type in women worldwide. Early detection and appropriate treatment can significantly reduce its impact. While histopathology examinations play a vital role in rapid and accurate diagnosis, they often…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Nematollah Saeidi , Hossein Karshenas , Bijan Shoushtarian , Sepideh Hatamikia , Ramona Woitek , Amirreza Mahbod

Feature selection (FS) is essential for biomarker discovery and clinical predictive modeling. Over the past decades, methodological literature on FS has become rich and mature, offering a wide spectrum of algorithmic approaches. However,…

Cancer screening, leading to early detection, saves lives. Unfortunately, existing screening techniques require expensive and intrusive medical procedures, not globally available, resulting in too many lost would-be-saved lives. We present…

Machine Learning · Computer Science 2025-09-29 Liwen Sun , Hao-Ren Yao , Gary Gao , Ophir Frieder , Chenyan Xiong

We propose and evaluate a novel method for automatically detecting clinically significant prostate cancer (csPCa) in bi-parametric magnetic resonance imaging (bpMRI). Prostate zones play an important role in the assessment of prostate…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Matin Hosseinzadeh , Patrick Brand , Henkjan Huisman

We hypothesize that anatomical priors can be viable mediums to infuse domain-specific clinical knowledge into state-of-the-art convolutional neural networks (CNN) based on the U-Net architecture. We introduce a probabilistic population…

Image and Video Processing · Electrical Eng. & Systems 2021-09-22 Anindo Saha , Matin Hosseinzadeh , Henkjan Huisman

Deep learning models have had a great success in disease classifications using large data pools of skin cancer images or lung X-rays. However, data scarcity has been the roadblock of applying deep learning models directly on prostate…

Computer Vision and Pattern Recognition · Computer Science 2021-01-27 Weiwei Zong , Joon Lee , Chang Liu , Eric Carver , Aharon Feldman , Branislava Janic , Mohamed Elshaikh , Milan Pantelic , David Hearshen , Indrin Chetty , Benjamin Movsas , Ning Wen

Data driven approaches have the potential to make modeling complex, nonlinear physical phenomena significantly more computationally tractable. For example, computational modeling of fracture is a core challenge where machine learning…

Machine Learning · Computer Science 2025-10-01 Erfan Hamdi , Emma Lejeune

Artificial intelligence foundation models are increasingly deployed for prostate cancer Gleason grading, where GP3/GP4 distinction directly impacts treatment decisions. However, these models may achieve high validation accuracy by learning…

Computer Vision and Pattern Recognition · Computer Science 2025-12-18 Joshua L. Ebbert , Dennis Della Corte

Prostate cancer is one of the leading causes of cancer-related death in men worldwide. Like many cancers, diagnosis involves expert integration of heterogeneous patient information such as imaging, clinical risk factors, and more. For this…

Image and Video Processing · Electrical Eng. & Systems 2023-10-02 Gregory Holste , Douwe van der Wal , Hans Pinckaers , Rikiya Yamashita , Akinori Mitani , Andre Esteva

In patients with biochemical recurrence of prostate cancer and negative PSMA PET/CT, radiomics features extracted from recurrence-prone organs can predict clinical progression and progression-free survival. In a cohort of 132 patients,…

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Photoplethysmography (PPG) sensor in wearable and clinical devices provides valuable physiological insights in a non-invasive and real-time fashion. Specialized Foundation Models (FM) or repurposed time-series FMs are used to benchmark…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Saurabh Kataria , Ayca Ermis , Lovely Yeswanth Panchumarthi , Minxiao Wang , Xiao Hu