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Convolutional Neural Networks (CNN) have had a huge success in many areas of computer vision and medical image analysis. However, there is still an immense potential for performance improvement in mammogram breast cancer detection…

Computer Vision and Pattern Recognition · Computer Science 2018-08-28 Yeman Brhane Hagos , Albert Gubern Merida , Jonas Teuwen

Despite the growing clinical adoption of large language models (LLMs), current approaches heavily rely on single model architectures. To overcome risks of obsolescence and rigid dependence on single model systems, we present a novel…

Artificial Intelligence · Computer Science 2025-06-24 Amit Kumthekar , Zion Tilley , Henry Duong , Bhargav Patel , Michael Magnoli , Ahmed Omar , Ahmed Nasser , Chaitanya Gharpure , Yevgen Reztzov

The Abstraction and Reasoning Corpus (ARC-AGI) has become a key benchmark for fluid intelligence in AI. This survey presents the first cross-generation analysis of 82 approaches across three benchmark versions and the ARC Prize 2024-2025…

Artificial Intelligence · Computer Science 2026-03-17 Sahar Vahdati , Andrei Aioanei , Haridhra Suresh , Jens Lehmann

This paper quantitatively reveals the state-of-the-art and state-of-the-practice AI systems only achieve acceptable performance on the stringent conditions that all categories of subjects are known, which we call closed clinical settings,…

Advances in artificial intelligence (AI) show great potential in revealing underlying information from phonon microscopy (high-frequency ultrasound) data to identify cancerous cells. However, this technology suffers from the 'batch effect'…

Quantitative Methods · Quantitative Biology 2024-03-28 Yijie Zheng , Rafael Fuentes-Dominguez , Matt Clark , George S. D. Gordon , Fernando Perez-Cota

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

The paper investigates the feasibility of confidence estimation for neural machine translation models operating at the high end of the performance spectrum. As a side product of the data annotation process necessary for building such models…

Computation and Language · Computer Science 2020-10-28 Ciprian Chelba , Junpei Zhou , Yuezhang , Li , Hideto Kazawa , Jeff Klingner , Mengmeng Niu

Translating the vast data generated by genomic platforms into reliable predictions of clinical outcomes remains a critical challenge in realizing the promise of genomic medicine largely due to small number of independent samples. In this…

Quantitative Methods · Quantitative Biology 2019-04-04 Safoora Yousefi , Amirreza Shaban , Mohamed Amgad , Ramraj Chandradevan , Lee A. D. Cooper

Background: The 2022 update of the Ovarian-Adnexal Reporting and Data System (O-RADS) ultrasound classification refines risk stratification for adnexal lesions, yet human interpretation remains subject to variability and conservative…

The Receiver Operating Characteristic (ROC) curve and the Area Under the Curve (AUC) of the ROC curve are widely used to compare the performance of diagnostic and prognostic assays. The ROC curve has the advantage that it is independent of…

Ensuring trustworthiness is fundamental to the development of artificial intelligence (AI) that is considered societally responsible, particularly in cancer diagnostics, where a misdiagnosis can have dire consequences. Current digital…

Image and Video Processing · Electrical Eng. & Systems 2025-01-03 Xiaoge Zhang , Tao Wang , Chao Yan , Fedaa Najdawi , Kai Zhou , Yuan Ma , Yiu-ming Cheung , Bradley A. Malin

Delineating the clinical target volume (CTV) in radiotherapy involves complex margins constrained by tumor location and anatomical barriers. While deep learning models automate this process, their rigid reliance on expert-annotated data…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Yoon Jo Kim , Wonyoung Cho , Jongmin Lee , Han Joo Chae , Hyunki Park , Sang Hoon Seo , Noh Jae Myung , Kyungmi Yang , Dongryul Oh , Jin Sung Kim

We propose the molecular omics network (MOOMIN) a multimodal graph neural network used by AstraZeneca oncologists to predict the synergy of drug combinations for cancer treatment. Our model learns drug representations at multiple scales…

Machine Learning · Computer Science 2022-08-09 Benedek Rozemberczki , Anna Gogleva , Sebastian Nilsson , Gavin Edwards , Andriy Nikolov , Eliseo Papa

In high-stakes risk prediction, quantifying uncertainty through interval-valued predictions is essential for reliable decision-making. However, standard evaluation tools like the receiver operating characteristic (ROC) curve and the area…

Machine Learning · Computer Science 2026-02-05 Yuqi Li , Matthew M. Engelhard

Interference alignment (IA) is known to significantly increase sum-throughput at high SNR in the presence of multiple interfering nodes, however, the reliability of IA is little known, which is the subject of this paper. We study the error…

Information Theory · Computer Science 2012-11-28 Baile Xie , Yang Li , Hlaing Minn , Aria Nosratinia

Deep learning systems frequently fail at out-of-context (OOC) prediction, the problem of making reliable predictions on uncommon or unusual inputs or subgroups of the training distribution. To this end, a number of benchmarks for measuring…

Machine Learning · Computer Science 2021-10-27 David Madras , Richard Zemel

Motivation: Multi-omics integration can improve cancer subtyping, but modality informativeness and noise vary across cancer types and patients. Existing graph-based methods optimize modality weights jointly with the classification objective…

Machine Learning · Computer Science 2026-04-28 Boyang Fan , Hengchuang Yin , Siyu Yi , Yifan Wang , Zhicheng Li , Leijiyu Zhou , Jiancheng Lv , Wei Ju

Artificial intelligence (AI) is transforming cancer diagnosis and treatment. The intricate nature of this disease necessitates the collaboration of diverse stakeholders with varied expertise to ensure the effectiveness of cancer research.…

Digital Libraries · Computer Science 2025-12-30 Shahab Mosallaie , Andrea Schiffauerova , Ashkan Ebadi

The area under the receiver-operating characteristic curve (AUC) has become a popular index not only for measuring the overall prediction capacity of a marker but also the association strength between continuous and binary variables. In the…

The precision of contouring target structures and organs-at-risk (OAR) in radiotherapy planning is crucial for ensuring treatment efficacy and patient safety. Recent advancements in deep learning (DL) have significantly improved OAR…

Image and Video Processing · Electrical Eng. & Systems 2024-09-30 Marvin Tom Teichmann , Manasi Datar , Lisa Kratzke , Fernando Vega , Florin C. Ghesu
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