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The versatility of large language models (LLMs) has been explored across various sectors, but their application in healthcare poses challenges, particularly in the domain of pharmaceutical contraindications where accurate and reliable…

Artificial Intelligence · Computer Science 2025-08-11 Byeonghun Bang , Jongsuk Yoon , Dong-Jin Chang , Seho Park , Yong Oh Lee

Synthetic data generation (SDG) is a promising approach for enabling data sharing in biomedical studies while preserving patient privacy. Yet, state-of-the-art generative models often require large datasets and complex training procedures,…

Machine Learning · Computer Science 2026-01-27 Natalia Espinosa-Dice , Nicholas J. Jackson , Chao Yan , Aaron Lee , Bradley A. Malin

This paper explores the use of large language models (LLMs) to assist in the development of new disease modules for Synthea, an open-source synthetic health data generator. Incorporating LLMs into the module development process has the…

Artificial Intelligence · Computer Science 2025-07-30 Mark A. Kramer , Aanchal Mathur , Caroline E. Adams , Jason A. Walonoski

Despite significant progress in applying large language models (LLMs) to the medical domain, several limitations still prevent them from practical applications. Among these are the constraints on model size and the lack of cohort-specific…

Artificial Intelligence · Computer Science 2024-09-26 Yishu Wei , Xindi Wang , Hanley Ong , Yiliang Zhou , Adam Flanders , George Shih , Yifan Peng

Training and fine-tuning deep learning models, especially large language models (LLMs), on limited and imbalanced datasets poses substantial challenges. These issues often result in poor generalization, where models overfit to dominant…

Computation and Language · Computer Science 2025-01-14 Ashok Choudhary , Cornelius Thiels , Hojjat Salehinejad

An increasingly common practice is to train large language models (LLMs) using synthetic data. Often this synthetic data is produced by the same or similar LLMs as those it is being used to train. This raises the question of whether the…

Computation and Language · Computer Science 2025-03-18 Lingze Zhang , Ellie Pavlick

Retrieval-Augmented Generation (RAG) is a promising approach to mitigate hallucinations in Large Language Models (LLMs) for legal applications, but its reliability is critically dependent on the accuracy of the retrieval step. This is…

Computation and Language · Computer Science 2025-10-09 Markus Reuter , Tobias Lingenberg , Rūta Liepiņa , Francesca Lagioia , Marco Lippi , Giovanni Sartor , Andrea Passerini , Burcu Sayin

Large language models (LLMs) encapsulate a vast amount of factual information within their pre-trained weights, as evidenced by their ability to answer diverse questions across different domains. However, this knowledge is inherently…

Artificial Intelligence · Computer Science 2024-01-31 Oded Ovadia , Menachem Brief , Moshik Mishaeli , Oren Elisha

Prior research on training grounded factuality classification models to detect hallucinations in large language models (LLMs) has relied on public natural language inference (NLI) data and synthetic data. However, conventional NLI datasets…

Computation and Language · Computer Science 2025-01-29 Deren Lei , Yaxi Li , Siyao Li , Mengya Hu , Rui Xu , Ken Archer , Mingyu Wang , Emily Ching , Alex Deng

The in-context learning ability of large language models (LLMs) enables them to generalize to novel downstream tasks with relatively few labeled examples. However, they require enormous computational resources to be deployed. Alternatively,…

Computation and Language · Computer Science 2024-01-09 Jean Kaddour , Qi Liu

The issues that must be considered regarding the utilization of synthetic data generated through LLMs for multilabel patent classification include (i) when the use of such data may help and (ii) why. Indeed, the former part appropriately…

Artificial Intelligence · Computer Science 2026-05-27 Amirhossein Yousefiramandi , Ciaran Cooney

Large Multimodal Models (LMMs), or Vision-Language Models (VLMs), have shown impressive capabilities in a wide range of visual tasks. However, they often struggle with fine-grained visual reasoning, failing to identify domain-specific…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Yucheng Shi , Quanzheng Li , Jin Sun , Xiang Li , Ninghao Liu

Retrieval-augmented generation (RAG) enhances large language models (LLMs) by integrating external knowledge retrieved from a knowledge base. However, its effectiveness is fundamentally constrained by the reliability of both the retriever…

Computation and Language · Computer Science 2025-01-31 Yiteng Tu , Weihang Su , Yujia Zhou , Yiqun Liu , Qingyao Ai

Large language model (LLM) agents are increasingly employing retrieval-augmented generation (RAG) to improve the factuality of their responses. However, in practice, these systems often need to handle ambiguous user queries and potentially…

Computation and Language · Computer Science 2025-08-13 Han Wang , Archiki Prasad , Elias Stengel-Eskin , Mohit Bansal

Large Language Models (LLMs) offer a flexible means to generate synthetic tabular data, yet existing approaches often fail to preserve key causal parameters such as the average treatment effect (ATE). In this technical exploration, we first…

Machine Learning · Computer Science 2025-11-04 Dana Kim , Yichen Xu , Tiffany Lin

Language Models (LMs) memorize a vast amount of factual knowledge, exhibiting strong performance across diverse tasks and domains. However, it has been observed that the performance diminishes when dealing with less-popular or low-frequency…

Computation and Language · Computer Science 2024-12-03 Heydar Soudani , Evangelos Kanoulas , Faegheh Hasibi

Error correction is an important capability when applying large language models (LLMs) to facilitate user typing on mobile devices. In this paper, we use LLMs to synthesize a high-quality dataset of error correction pairs to evaluate and…

Machine Learning · Computer Science 2025-05-27 Yanxiang Zhang , Zheng Xu , Shanshan Wu , Yuanbo Zhang , Daniel Ramage

Large Language Models (LLMs) have the unique capability to understand and generate human-like text from input queries. When fine-tuned, these models show enhanced performance on domain-specific queries. OpenAI highlights the process of…

Computation and Language · Computer Science 2024-07-02 Scott Barnett , Zac Brannelly , Stefanus Kurniawan , Sheng Wong

Large language models (LLMs) can be leveraged to help with writing formulas in spreadsheets, but resources on these formulas are scarce, impacting both the base performance of pre-trained models and limiting the ability to fine-tune them.…

Computation and Language · Computer Science 2025-07-14 Usneek Singh , José Cambronero , Sumit Gulwani , Aditya Kanade , Anirudh Khatry , Vu Le , Mukul Singh , Gust Verbruggen

Utility companies increasingly rely on drone imagery for post-event and routine inspection, but training accurate defect-type classifiers remains difficult because defect examples are rare and inspection datasets are often limited or…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Xuesong Wang , Caisheng Wang
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