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The dynamic characteristics of functional network connectivity have been widely acknowledged and studied. Both shared and unique information has been shown to be present in the connectomes. However, very little has been known about whether…

Neurons and Cognition · Quantitative Biology 2020-06-18 Biao Cai , Gemeng Zhang , Aiying Zhang , Li Xiao , Wenxing Hu , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

The evaluation of the individual 'fingerprint' of a human functional connectome (FC) is becoming a promising avenue for neuroscientific research, due to its enormous potential inherent to drawing single subject inferences from functional…

Neurons and Cognition · Quantitative Biology 2018-04-13 Enrico Amico , Joaquín Goñi

The human brain is a complex network comprised of functionally and anatomically interconnected brain regions. A growing number of studies have suggested that empirical estimates of brain networks may be useful for discovery of biomarkers of…

Neurons and Cognition · Quantitative Biology 2022-11-15 Andrew Hannum , Mario A. Lopez , Saúl A. Blanco , Richard F. Betzel

Functional connectivity quantifies the statistical dependencies between the activity of brain regions, measured using neuroimaging data such as functional MRI BOLD time series. The network representation of functional connectivity, called a…

Neurons and Cognition · Quantitative Biology 2020-11-23 Benjamin Chiêm , Kausar Abbas , Enrico Amico , Duy Anh Duong-Tran , Frédéric Crevecoeur , Joaquín Goñi

The assessment of brain fingerprints has emerged in the recent years as an important tool to study individual differences and to infer quality of neuroimaging datasets. Studies so far have mainly focused on connectivity fingerprints between…

Neurons and Cognition · Quantitative Biology 2021-01-13 Uttara Tipnis , Kausar Abbas , Elizabeth Tran , Enrico Amico , Li Shen , Alan D. Kaplan , Joaquín Goñi

It has been well established that Functional Connectomes (FCs), as estimated from functional MRI (fMRI) data, have an individual fingerprint that can be used to identify an individual from a population (subject-identification). Although…

Recent neuroimaging studies have shown that functional connectomes are unique to individuals, i.e., two distinct fMRIs taken over different sessions of the same subject are more similar in terms of their connectomes than those from two…

Computer Vision and Pattern Recognition · Computer Science 2019-08-12 Vikram Ravindra , Petros Drineas , Ananth Grama

Multi-site studies are becoming important to increase statistical power, enhance generalizability, and to improve the likelihood of pooling relevant subgroups together activities. Even with harmonized imaging sequences, site-dependent…

Neurons and Cognition · Quantitative Biology 2019-09-11 Sumra Bari , Enrico Amico , Nicole Vike , Thomas M. Talavage , Joaquín Goñi

Functional connectivity, as estimated using resting state fMRI, has shown potential in bridging the gap between pathophysiology and cognition. However, clinical use of functional connectivity biomarkers is impeded by unreliable estimates of…

Distinguishing one person from another (what biometricians call recognition) is extremely relevant for different aspects of life. Traditional biometric modalities (fingerprint, face, iris, voice) rely on unique, stable features that…

Quantitative Methods · Quantitative Biology 2025-06-09 Matteo Fraschini , Matteo Demuru , Daniele Marinazzo , Luca Didaci

The increasing popularity of naturalistic paradigms in fMRI (such as movie watching) demands novel strategies for multi-subject data analysis, such as use of neural encoding models. In the present study, we propose a shared convolutional…

Neurons and Cognition · Quantitative Biology 2020-07-14 Meenakshi Khosla , Gia H. Ngo , Keith Jamison , Amy Kuceyeski , Mert R. Sabuncu

Functional magnetic resonance (fMRI) is an invaluable tool in studying cognitive processes in vivo. Many recent studies use functional connectivity (FC), partial correlation connectivity (PC), or fMRI-derived brain networks to predict…

Neurons and Cognition · Quantitative Biology 2023-08-04 Anton Orlichenko , Gang Qu , Kuan-Jui Su , Anqi Liu , Hui Shen , Hong-Wen Deng , Yu-Ping Wang

Predicting behavioral variables from neuroimaging modalities such as magnetic resonance imaging (MRI) has the potential to allow the development of neuroimaging biomarkers of mental and neurological disorders. A crucial processing step to…

Neurons and Cognition · Quantitative Biology 2025-07-29 Mikkel Schöttner Sieler , Thomas A. W. Bolton , Jagruti Patel , Patric Hagmann

We analyze functional magnetic resonance imaging (fMRI) data from the Human Connectome Project (HCP) to match brain activities during a range of cognitive tasks. Our findings demonstrate that even basic linear machine learning models can…

Neurons and Cognition · Quantitative Biology 2025-10-08 Valeriya Kirova , Dzerassa Kadieva , Daniil Vlasenko , Isak B. Blank , Fedor Ratnikov

We propose a novel denoising framework for task functional Magnetic Resonance Imaging (tfMRI) data to delineate the high-resolution spatial pattern of the brain functional connectivity via dictionary learning and sparse coding (DLSC). In…

Machine Learning · Computer Science 2017-07-24 Seongah Jeong , Xiang Li , Jiarui Yang , Quanzheng Li , Vahid Tarokh

Functional connectomes (FCs) contain pairwise estimations of functional couplings based on pairs of brain regions activity. FCs are commonly represented as correlation matrices that are symmetric positive definite (SPD) lying on or inside…

Accounting for inter-individual variability in brain function is key to precision medicine. Here, by considering functional inter-individual variability as meaningful data rather than noise, we introduce VarCoNet, an enhanced…

Neural and Evolutionary Computing · Computer Science 2025-10-06 Charalampos Lamprou , Aamna Alshehhi , Leontios J. Hadjileontiadis , Mohamed L. Seghier

Functional MRI (fMRI) and diffusion MRI (dMRI) are non-invasive imaging modalities that allow in-vivo analysis of a patient's brain network (known as a connectome). Use of these technologies has enabled faster and better diagnoses and…

Machine Learning · Computer Science 2016-12-06 Colin J Brown , Ghassan Hamarneh

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

Neurons and Cognition · Quantitative Biology 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

In recent years, analyzing task-based fMRI (tfMRI) data has become an essential tool for understanding brain function and networks. However, due to the sheer size of tfMRI data, its intrinsic complex structure, and lack of ground truth of…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-03-06 Milad Makkie , Heng Huang , Yu Zhao , Athanasios V. Vasilakos , Tianming Liu
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