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The convergence of statistical learning and molecular physics is transforming our approach to modeling biomolecular systems. Physics-informed machine learning (PIML) offers a systematic framework that integrates data-driven inference with…

Biomolecules · Quantitative Biology 2025-11-11 Aaryesh Deshpande

Recent advances of data-driven machine learning have revolutionized fields like computer vision, reinforcement learning, and many scientific and engineering domains. In many real-world and scientific problems, systems that generate data are…

Machine Learning · Computer Science 2023-03-08 Zhongkai Hao , Songming Liu , Yichi Zhang , Chengyang Ying , Yao Feng , Hang Su , Jun Zhu

Physics-informed machine learning (PIML) is a set of methods and tools that systematically integrate machine learning (ML) algorithms with physical constraints and abstract mathematical models developed in scientific and engineering…

Physics-informed machine learning (PIML), referring to the combination of prior knowledge of physics, which is the high level abstraction of natural phenomenons and human behaviours in the long history, with data-driven machine learning…

Machine Learning · Computer Science 2022-04-01 Chuizheng Meng , Sungyong Seo , Defu Cao , Sam Griesemer , Yan Liu

Physics-informed machine learning (PIML) is emerging as a potentially transformative paradigm for modeling complex biomedical systems by integrating parameterized physical laws with data-driven methods. Here, we review three main classes of…

Machine Learning · Computer Science 2025-10-08 Nazanin Ahmadi , Qianying Cao , Jay D. Humphrey , George Em Karniadakis

This study presents a comprehensive overview of PIML techniques in the context of condition monitoring. The central concept driving PIML is the incorporation of known physical laws and constraints into machine learning algorithms, enabling…

Machine Learning · Computer Science 2024-01-23 Yuandi Wu , Brett Sicard , Stephen Andrew Gadsden

Physics-informed machine learning (PIML) represents an emerging paradigm that integrates various forms of physical knowledge into machine learning (ML) components, thereby enhancing the physical consistency of ML models compared to purely…

Chemical Physics · Physics 2025-10-28 Jiahao Wu , Xutun Wang , Guihua Zhang , Jiayue Liu , Xin Li , Yang Zhang , Hai Zhang , Junfu Lyu , Bing Wang , Yuxin Wu

Physics-Informed Machine Learning (PIML) offers a powerful paradigm of integrating data with physical laws to address important scientific problems, such as parameter estimation, inferring hidden physics, equation discovery, and state…

Computational Engineering, Finance, and Science · Computer Science 2025-10-31 Letian Yi , Siyuan Yang , Ying Cui , Zhilu Lai

Physics-informed machine learning (PIML) is an emerging framework that integrates physical knowledge into machine learning models. This physical prior often takes the form of a partial differential equation (PDE) system that the regression…

Machine Learning · Statistics 2025-07-15 Nathan Doumèche

This position paper takes a broad look at Physics-Enhanced Machine Learning (PEML) -- also known as Scientific Machine Learning -- with particular focus to those PEML strategies developed to tackle dynamical systems' challenges. The need to…

Machine Learning · Computer Science 2024-12-30 Alice Cicirello

Physics-Informed Machine Learning (PIML) has gained momentum in the last 5 years with scientists and researchers aiming to utilize the benefits afforded by advances in machine learning, particularly in deep learning. With large scientific…

Computational Physics · Physics 2021-05-26 Samuel J. Raymond , David B. Camarillo

Building performance simulation (BPS) is critical for understanding building dynamics and behavior, analyzing performance of the built environment, optimizing energy efficiency, improving demand flexibility, and enhancing building…

Systems and Control · Electrical Eng. & Systems 2025-05-26 Zixin Jiang , Xuezheng Wang , Han Li , Tianzhen Hong , Fengqi You , Ján Drgoňa , Draguna Vrabie , Bing Dong

Compared to physics-based computational manufacturing, data-driven models such as machine learning (ML) are alternative approaches to achieve smart manufacturing. However, the data-driven ML's "black box" nature has presented a challenge to…

Machine Learning · Computer Science 2024-07-16 Rahul Sharma , Maziar Raissi , Y. B. Guo

Scientific Machine Learning (SciML) is a recently emerged research field which combines physics-based and data-driven models for the numerical approximation of differential problems. Physics-based models rely on the physical understanding…

Numerical Analysis · Mathematics 2025-04-04 Alfio Quarteroni , Paola Gervasio , Francesco Regazzoni

Machine learning has emerged as a powerful tool in various fields, including computer vision, natural language processing, and speech recognition. It can unravel hidden patterns within large data sets and reveal unparalleled insights,…

Machine Learning · Computer Science 2024-05-24 Abdeldjalil Latrach , Mohamed Lamine Malki , Misael Morales , Mohamed Mehana , Minou Rabiei

Advancements in digital automation for smart grids have led to the installation of measurement devices like phasor measurement units (PMUs), micro-PMUs ($\mu$-PMUs), and smart meters. However, a large amount of data collected by these…

Systems and Control · Electrical Eng. & Systems 2023-09-20 Mehdi Jabbari Zideh , Paroma Chatterjee , Anurag K. Srivastava

We are delighted to see the recent development of physics-informed extreme learning machine (PIELM) for its higher computational efficiency and accuracy compared to other physics-informed machine learning (PIML) paradigms. Since a…

Machine Learning · Computer Science 2025-11-04 He Yang , Fei Ren , Francesco Calabro , Hai-Sui Yu , Xiaohui Chen , Pei-Zhi Zhuang

The mass loss of the polar ice sheets contributes considerably to ongoing sea-level rise and changing ocean circulation, leading to coastal flooding and risking the homes and livelihoods of tens of millions of people globally. To address…

Machine Learning · Computer Science 2024-05-01 Zesheng Liu , YoungHyun Koo , Maryam Rahnemoonfar

Current hydrological modeling methods combine data-driven Machine Learning (ML) algorithms and traditional physics-based models to address their respective limitations incorrect parameter estimates from rigid physics-based models and the…

Machine Learning · Computer Science 2024-02-22 Mostafa Esmaeilzadeh , Melika Amirzadeh

Fueled by breakthrough technology developments, the biological, biomedical, and behavioral sciences are now collecting more data than ever before. There is a critical need for time- and cost-efficient strategies to analyze and interpret…

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