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Mathematical models of infectious disease transmission typically neglect within-host dynamics. Yet within-host dynamics - including pathogen replication, host immune responses, and interactions with microbiota - are crucial not only for…

Populations and Evolution · Quantitative Biology 2023-12-20 Cameron A. Smith , Ben Ashby

In this work, the spread of a contagious disease on a society where the individuals may take precautions is modeled. The primary assumption is that the infected individuals transmit the infection to the susceptible members of the community…

Physics and Society · Physics 2021-03-16 Semra Gunduc

The importance of spatial networks in the spread of an epidemic is an essential aspect in modeling the dynamics of an infectious disease. Additionally, any realistic data-driven model must take into account the large uncertainty in the…

Populations and Evolution · Quantitative Biology 2022-01-17 Giulia Bertaglia , Lorenzo Pareschi

Infection dynamics have been studied extensively on complex networks, yielding insight into the effects of heterogeneity in contact patterns on disease spread. Somewhat separately, metapopulations have provided a paradigm for modeling…

Physics and Society · Physics 2013-08-09 Jason Hindes , Sarabjeet Singh , Christopher R. Myers , David J. Schneider

Inter-city interactions are critical for the transmission of infectious diseases, yet their effects on the scaling of disease cases remain largely underexplored. Here, we use the commuting network as a proxy for inter-city interactions,…

Physics and Society · Physics 2025-01-06 Nathalia A. Loureiro , Camilo R. Neto , Jack Sutton , Matjaz Perc , Haroldo V. Ribeiro

To simplify mathematical models of disease spread, we often assume equal contact rates among hosts, but real-world scenarios differ. Network-based frameworks help capture these complexities and structural variations in actual systems. We…

Dynamical Systems · Mathematics 2024-07-03 Saswata Das , Mohammad Hossein Samaei , Caterina Scoglio

We propose a new model that describes the dynamics of epidemic spreading on connected graphs. Our model consists in a PDE-ODE system where at each vertex of the graph we have a standard SIR model and connexions between vertices are given by…

Analysis of PDEs · Mathematics 2020-11-25 Christophe Besse , Grégory Faye

This paper investigates the spread of infectious diseases within a networked community by integrating epidemic transmission and public opinion dynamics. We propose a novel discrete-time networked SIS (Susceptible-Infectious-Susceptible)…

Systems and Control · Electrical Eng. & Systems 2025-08-14 Qiulin Xu , Tatsuya Masada , Hideaki Ishii

In this paper we introduce an agent-based epidemiological model that generalizes the classical SIR model by Kermack and McKendrick. We further provide a multiscale approach to the derivation of a macroscopic counterpart via the mean-field…

Dynamical Systems · Mathematics 2022-03-31 Markus Schmidtchen , Oliver Tse , Stephan Wackerle

Recent work from public health experts suggests that incorporating human behavior is crucial in faithfully modeling an epidemic. We present a reaction-diffusion partial differential equation SIR-type population model for an epidemic…

Analysis of PDEs · Mathematics 2023-09-06 Christian Parkinson , Weinan Wang

An ultrametric model of epidemic spread of infections based on the classical SIR model is proposed. Ultrametrics on a set of individuals based on theire hierarchical clustering relativly to the average time of infectious contact is…

Physics and Society · Physics 2020-07-21 V. T. Volov , A. P. Zubarev

This study develops and analyzes an extended Susceptible, Infected, Hospitalized and Recovered (SIHR) model incorporating time dependent control functions to capture preventive measures (e.g., distancing, mask use) and resource limited…

Populations and Evolution · Quantitative Biology 2025-10-01 Liban Ismail , Yahyeh Souleiman , Saraless Nadarajah , Abdisalam Hassan

The ever-changing world of disease study heavily relies on mathematical models. They are key in finding and controlling infectious diseases. We aim to explore these mathematical tools used for studying disease spread in biology. The SEIR…

History and Overview · Mathematics 2025-01-03 Pabel Shahrear , Md. Shahedul Islam , Md. Abu Bakkar , Anika Bushra , Ismail Hossain

We develop a multiple compartment Susceptible-Infected-Recovered (SIR) model to analyze the spread of several infectious diseases through different geographic areas. Additionally, we propose a data-quality sensitive optimization framework…

Populations and Evolution · Quantitative Biology 2019-06-21 Inbar Seroussi , Nir Levy , Daniela Paolotti , Nir Sochen , Elad Yom-Tov

Religions are among the most consequential social institutions, shaping collective identities, moral norms, and political organization across societies and historical periods. Nevertheless, despite extensive scholarship describing…

Physics and Society · Physics 2026-01-19 Bilge Taskin , Teddy Lazebnik

Metapopulation models provide the theoretical framework for describing disease spread between different populations connected by a network. In particular, these models are at the basis of most simulations of pandemic spread. They are…

Disordered Systems and Neural Networks · Physics 2010-10-12 Marc Barthelemy , Claude Godreche , Jean-Marc Luck

Mathematical models represent one of the fundamental ways of studying nature. In special, epidemic models have shown to be particularly useful in the understanding of the course of diseases and in the planning effective control policies. A…

Physics and Society · Physics 2022-10-19 Paulo C. Ventura , Eric K. Tokuda , Luciano da F. Costa , Francisco A. Rodrigues

Epidemic models are invaluable tools to understand and implement strategies to control the spread of infectious diseases, as well as to inform public health policies and resource allocation. However, current modeling approaches have…

Methodology · Statistics 2026-05-12 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

During epidemic outbreaks, information dissemination enhances individual protection, while social institutions influence the transmission through measures like government interventions, media campaigns, and hospital resource allocation.…

Physics and Society · Physics 2025-06-03 Mengshou Wang , Liangrong Peng , Baoguo Jia , Liu Hong

Metapopulation epidemic models describe epidemic dynamics in networks of spatially distant patches connected with pathways for migration of individuals. In the present study, we deal with a susceptible-infected-recovered (SIR)…

Physics and Society · Physics 2019-08-22 Akari Matsuki , Gouhei Tanaka