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Related papers: Machine Learning based Analysis for Radiomics Feat…

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In the context of brain tumor characterization, we focused on two key questions: (a) stability of radiomics features to variability in multiregional segmentation masks obtained with fully-automatic deep segmentation methods and (b)…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Maria Nadeem , Asma Shaheen , Muhammad F. A. Chaudhary , Hassan Mohy-ud-Din

Radiomics enables quantitative medical image analysis by converting imaging data into structured, high-dimensional feature representations for predictive modeling. Despite methodological developments and encouraging retrospective results,…

Image and Video Processing · Electrical Eng. & Systems 2026-02-03 Fnu Neha , Deepak kumar Shukla

Identifying image features that are robust with respect to segmentation variability and domain shift is a tough challenge in radiomics. So far, this problem has mainly been tackled in test-retest analyses. In this work we analyze radiomics…

Image and Video Processing · Electrical Eng. & Systems 2020-01-22 Christoph Haarburger , Justus Schock , Daniel Truhn , Philippe Weitz , Gustav Mueller-Franzes , Leon Weninger , Dorit Merhof

Motivation: Radiomics refers to the high-throughput mining of quantitative features from radiographic images. It is a promising field in that it may provide a non-invasive solution for screening and classification. Standard machine learning…

Robust machine learning for regulatory genomics is studied under biologically and technically induced distribution shifts. Deep convolutional and attention based models achieve strong in distribution performance on DNA regulatory sequence…

Genomics · Quantitative Biology 2026-02-20 Yiyao Yang

Most machine learning methods assume that the input data distribution is the same in the training and testing phases. However, in practice, this stationarity is usually not met and the distribution of inputs differs, leading to unexpected…

Machine Learning · Computer Science 2023-04-19 Firas Bayram , Bestoun S. Ahmed

Background: The reproducibility of machine-learning models in prostate cancer detection across different MRI vendors remains a significant challenge. Methods: This study investigates Support Vector Machines (SVM) and Random Forest (RF)…

Most papers caution against using predictive models for disease stratification based on unselected radiomic features, as these features are affected by contouring variability. Instead, they advocate for the use of the Intraclass Correlation…

Due to the increase in computational resources and accessibility of data, an increase in large, deep learning models trained on copious amounts of multi-modal data using self-supervised or semi-supervised learning have emerged. These…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Madeline Chantry Schiappa , Shehreen Azad , Sachidanand VS , Yunhao Ge , Ondrej Miksik , Yogesh S. Rawat , Vibhav Vineet

Purpose: To develop a novel deep-learning model that integrates radiomics analysis in a multi-dimensional feature fusion workflow for glioblastoma (GBM) post-resection survival prediction. Methods: A cohort of 235 GBM patients with complete…

Medical Physics · Physics 2022-03-14 Zongsheng Hu , Zhenyu Yang , Haozhao Zhang , Eugene Vaios , Kyle Lafata , Fang-Fang Yin , Chunhao Wang

Robustness to distribution shifts is critical for deploying machine learning models in the real world. Despite this necessity, there has been little work in defining the underlying mechanisms that cause these shifts and evaluating the…

Every year, millions of patients pass through emergency departments and intensive care units, where clinicians must make high-stakes decisions under time pressure and uncertainty. Machine learning could support prediction of deterioration,…

Machine Learning · Computer Science 2026-05-27 Yusuf Brima , Marcellin Atemkeng

Background: As an important branch of machine learning pipelines in medical imaging, radiomics faces two major challenges namely reproducibility and accessibility. In this work, we introduce open-radiomics, a set of radiomics datasets along…

Quantitative Methods · Quantitative Biology 2025-03-04 Khashayar Namdar , Matthias W. Wagner , Birgit B. Ertl-Wagner , Farzad Khalvati

Pathology foundation models (PFMs) have emerged as powerful pretrained encoders for computational pathology, but their robustness under clinically relevant distribution shifts remains insufficiently understood. We benchmark the robustness…

Image and Video Processing · Electrical Eng. & Systems 2026-04-29 Fredrik K. Gustafsson , Mattias Rantalainen

We study whether deep networks for medical imaging learn useful nonrobust features - predictive input patterns that are not human interpretable and highly susceptible to small adversarial perturbations - and how these features impact test…

Image and Video Processing · Electrical Eng. & Systems 2026-04-27 Coenraad Mouton , Randle Rabe , Niklas C. Koser , Nicolai Krekiehn , Christopher Hansen , Jan-Bernd Hövener , Claus-C. Glüer

Despite achieving excellent performance on benchmarks, deep neural networks often underperform in real-world deployment due to sensitivity to minor, often imperceptible shifts in input data, known as distributional shifts. These shifts are…

Machine Learning · Computer Science 2025-09-25 Birk Torpmann-Hagen , Pål Halvorsen , Michael A. Riegler , Dag Johansen

Objectives: Glioblastomas are the most aggressive brain and central nervous system (CNS) tumors with poor prognosis in adults. The purpose of this study is to develop a machine-learning based classification method using radio-mic features…

Medical Physics · Physics 2019-11-25 Ge Cui , Jiwoong Jeong , Bob Press , Yang Lei , Hui-Kuo Shu , Tian Liu , Walter Curran , Hui Mao , Xiaofeng Yang

Clinical risk prediction models often underperform in real-world settings due to poor calibration, limited transportability, and subgroup disparities. These challenges are amplified in high-dimensional multimodal cancer datasets…

Machine Learning · Computer Science 2026-02-26 Toktam Khatibi

Distribution shifts are ubiquitous in real-world machine learning applications, posing a challenge to the generalization of models trained on one data distribution to another. We focus on scenarios where data distributions vary across…

Machine Learning · Statistics 2024-06-05 Steven Wilkins-Reeves , Xu Chen , Qi Ma , Christine Agarwal , Aude Hofleitner

Quantitative extraction of high-dimensional mineable data from medical images is a process known as radiomics. Radiomics is foreseen as an essential prognostic tool for cancer risk assessment and the quantification of intratumoural…

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