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Purpose: Electron density is the most important tissue property influencing photon and ion dose distributions in radiotherapy patients. Dual-energy computed tomography (DECT) enables the determination of electron density by combining the…

Medical Physics · Physics 2017-06-29 Christian Möhler , Patrick Wohlfahrt , Christian Richter , Steffen Greilich

Deep image prior (DIP) has been successfully applied to positron emission tomography (PET) image restoration, enabling represent implicit prior using only convolutional neural network architecture without training dataset, whereas the…

Medical Physics · Physics 2024-04-23 Yuya Onishi , Fumio Hashimoto , Kibo Ote , Keisuke Matsubara , Masanobu Ibaraki

Computed Tomography (CT) is a vital diagnostic tool in clinical practice, yet the health risks associated with ionizing radiation cannot be overlooked. Low-dose CT (LDCT) helps mitigate radiation exposure but simultaneously leads to reduced…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Guoliang Gong , Man Yu

To correct for respiratory motion in PET imaging, an interpretable and unsupervised deep learning technique, FlowNet-PET, was constructed. The network was trained to predict the optical flow between two PET frames from different breathing…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Teaghan O'Briain , Carlos Uribe , Kwang Moo Yi , Jonas Teuwen , Ioannis Sechopoulos , Magdalena Bazalova-Carter

Dual-energy computed tomography (CT) is to reconstruct images of an object from two projection datasets generated from two distinct x-ray source energy spectra. It can provide more accurate attenuation quantification than conventional CT…

Medical Physics · Physics 2018-05-15 Wenxiang Cong , Daniel Harrison , Yan Xi , Ge Wang

Convolutional neural networks (CNNs) have recently achieved remarkable performance in positron emission tomography (PET) image reconstruction. In particular, CNN-based direct PET image reconstruction, which directly generates the…

Medical Physics · Physics 2024-10-28 Fumio Hashimoto , Kibo Ote

Multi-energy computed tomography (CT) with photon counting detectors (PCDs) enables spectral imaging as PCDs can assign the incoming photons to specific energy channels. However, PCDs with many spectral channels drastically increase the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Satu I. Inkinen , Mikael A. K. Brix , Miika T. Nieminen , Simon Arridge , Andreas Hauptmann

The acquisition conditions for low-dose and high-dose CT images are usually different, so that the shifts in the CT numbers often occur. Accordingly, unsupervised deep learning-based approaches, which learn the target image distribution,…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Chanyong Jung , Joonhyung Lee , Sunkyoung You , Jong Chul Ye

Recent advances in imaging and high-performance computing have made it possible to image the entire human brain at the cellular level. This is the basis to study the multi-scale architecture of the brain regarding its subdivision into brain…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Jan-Oliver Kropp , Christian Schiffer , Katrin Amunts , Timo Dickscheid

Cone-beam CT (CBCT) is installed in the treatment room to facilitate online clinical applications, including image guidance in radiation and surgery. Half-fan and short-can are the commonly used modes in clinical applications to expand the…

Medical Physics · Physics 2022-05-24 Junbo Peng

Positron Emission Tomography (PET) is crucial in medicine, but its clinical use is limited due to high signal-to-noise ratio doses increasing radiation exposure. Lowering doses increases Poisson noise, which current denoising methods fail…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Yang Shi , Jingchao Wang , Liangsi Lu , Mingxuan Huang , Ruixin He , Yifeng Xie , Hanqian Liu , Minzhe Guo , Yangyang Liang , Weipeng Zhang , Zimeng Li , Xuhang Chen

Recent developments in artificial intelligence technology have enabled new developments that can improve attenuation and scatter correction in PET and SPECT. These technologies will enable the use of accurate and quantitative imaging…

Medical Physics · Physics 2021-08-30 Alan B. McMillan , Tyler J. Bradshaw

Reducing the radiation dose in computed tomography (CT) is important to mitigate radiation-induced risks. One option is to employ a well-trained model to compensate for incomplete information and map sparse-view measurements to the CT…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 Xiaoyue Li , Kai Shang , Gaoang Wang , Mark D. Butala

Low-resolution and signal-dependent noise distribution in positron emission tomography (PET) images makes denoising process an inevitable step prior to qualitative and quantitative image analysis tasks. Conventional PET denoising methods…

Computer Vision and Pattern Recognition · Computer Science 2014-07-14 Awais Mansoor , Ulas Bagci , Daniel J. Mollura

Ultra-low-dose positron emission tomography (PET) reconstruction holds significant potential for reducing patient radiation exposure and shortening examination times. However, it may also lead to increased noise and reduced imaging detail,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Mengxiao Geng , Ran Hong , Bingxuan Li , Qiegen Liu

The dose of X-ray radiation and the scanning time are crucial factors in computed tomography (CT) for clinical applications. In this work, we introduce a multi-source static CT imaging system designed to rapidly acquire sparse view and…

Medical Physics · Physics 2025-01-03 Ziju Shen , Haimiao Zhang , Bin Dong , Jun Qiu , Yunxiang Li , Zhili Cui

Quantitative PET attenuation correction (AC) for combined cardiac PET/MR is a challenging problem. We propose and evaluate an AC approach that uses coincidences from a relatively weak and physically fixed sparse external source, in…

Medical Physics · Physics 2023-01-02 Mi-Ae Park , Vlad G. Zaha , Ramsey D. Badawi , Spencer L. Bowen

Positron Emission Tomography and Magnetic Resonance Imaging (PET-MRI) systems can obtain functional and anatomical scans. PET suffers from a low signal-to-noise ratio. Meanwhile, the k-space data acquisition process in MRI is…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Taofeng Xie , Zhuo-Xu Cui , Chen Luo , Huayu Wang , Congcong Liu , Yuanzhi Zhang , Xuemei Wang , Yanjie Zhu , Guoqing Chen , Dong Liang , Qiyu Jin , Yihang Zhou , Haifeng Wang

Access to high-quality datasets in the medical industry limits machine learning model performance. To address this issue, we propose a Denoising Diffusion Probabilistic Model (DDPM) combined with a UNet architecture for X-ray image…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Praveen Mahaulpatha , Thulana Abeywardane , Tomson George

Breast cancer is the most prevalent cancer among women worldwide, and early detection is crucial for reducing its mortality rate and improving quality of life. Dedicated breast computed tomography (CT) scanners offer better image quality…

Image and Video Processing · Electrical Eng. & Systems 2024-01-30 Wenjun Xia , Hsin Wu Tseng , Chuang Niu , Wenxiang Cong , Xiaohua Zhang , Shaohua Liu , Ruola Ning , Srinivasan Vedantham , Ge Wang
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