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Large language models (LLMs) have shown remarkable capabilities in Natural Language Processing (NLP), especially in domains where labeled data is scarce or expensive, such as clinical domain. However, to unlock the clinical knowledge hidden…

Computation and Language · Computer Science 2023-09-18 Sonish Sivarajkumar , Mark Kelley , Alyssa Samolyk-Mazzanti , Shyam Visweswaran , Yanshan Wang

Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

Computation and Language · Computer Science 2026-04-13 Xiaohan Ren , Chenxiao Fan , Wenyin Ma , Hongliang He , Chongming Gao , Xiaoyan Zhao , Fuli Feng

Continuing advances in Large Language Models (LLMs) in artificial intelligence offer important capacities in intuitively accessing and using medical knowledge in many contexts, including education and training as well as assessment and…

Computation and Language · Computer Science 2024-08-01 Roma Shusterman , Allison C. Waters , Shannon O`Neill , Phan Luu , Don M. Tucker

Recent works on large language models (LLMs) have demonstrated the impact of prompting strategies and fine-tuning techniques on their reasoning capabilities. Yet, their effectiveness on clinical natural language inference (NLI) remains…

Computation and Language · Computer Science 2025-07-08 Mael Jullien , Marco Valentino , Leonardo Ranaldi , Andre Freitas

There are two main barriers to using large language models (LLMs) in clinical reasoning. Firstly, while LLMs exhibit significant promise in Natural Language Processing (NLP) tasks, their performance in complex reasoning and planning falls…

Artificial Intelligence · Computer Science 2024-12-31 Shengxin Hong , Liang Xiao , Xin Zhang , Jianxia Chen

The use of LLMs in natural language reasoning has shown mixed results, sometimes rivaling or even surpassing human performance in simpler classification tasks while struggling with social-cognitive reasoning, a domain where humans naturally…

Computation and Language · Computer Science 2024-10-23 Fiona Anting Tan , Gerard Christopher Yeo , Kokil Jaidka , Fanyou Wu , Weijie Xu , Vinija Jain , Aman Chadha , Yang Liu , See-Kiong Ng

Large Language Models (LLMs) are increasingly adopted for applications in healthcare, reaching the performance of domain experts on tasks such as question answering and document summarisation. Despite their success on these tasks, it is…

Computation and Language · Computer Science 2025-05-20 Aishik Nagar , Viktor Schlegel , Thanh-Tung Nguyen , Hao Li , Yuping Wu , Kuluhan Binici , Stefan Winkler

One of the major barriers to using large language models (LLMs) in medicine is the perception they use uninterpretable methods to make clinical decisions that are inherently different from the cognitive processes of clinicians. In this…

Computation and Language · Computer Science 2023-08-15 Thomas Savage , Ashwin Nayak , Robert Gallo , Ekanath Rangan , Jonathan H Chen

We introduce Meta-Reasoning Prompting (MRP), a novel and efficient system prompting method for large language models (LLMs) inspired by human meta-reasoning. Traditional in-context learning-based reasoning techniques, such as…

Computation and Language · Computer Science 2024-06-18 Peizhong Gao , Ao Xie , Shaoguang Mao , Wenshan Wu , Yan Xia , Haipeng Mi , Furu Wei

Traditionally, natural language processing (NLP) models often use a rich set of features created by linguistic expertise, such as semantic representations. However, in the era of large language models (LLMs), more and more tasks are turned…

Computation and Language · Computer Science 2024-05-03 Zhijing Jin , Yuen Chen , Fernando Gonzalez , Jiarui Liu , Jiayi Zhang , Julian Michael , Bernhard Schölkopf , Mona Diab

Large Language Models (LLMs) are powerful computational models trained on extensive corpora of human-readable text, enabling them to perform general-purpose language understanding and generation. LLMs have garnered significant attention in…

Computation and Language · Computer Science 2024-10-28 Liam Barkley , Brink van der Merwe

Role-playing has emerged as an effective technique for enhancing the reasoning capabilities of large language models (LLMs). However, existing methods primarily rely on prompt engineering, which often lacks stability and interpretability.…

Computation and Language · Computer Science 2025-09-30 Anyi Wang , Dong Shu , Yifan Wang , Yunpu Ma , Mengnan Du

Prompt learning is a new paradigm in the Natural Language Processing (NLP) field which has shown impressive performance on a number of natural language tasks with common benchmarking text datasets in full, few-shot, and zero-shot…

Computation and Language · Computer Science 2022-05-12 Niall Taylor , Yi Zhang , Dan Joyce , Alejo Nevado-Holgado , Andrey Kormilitzin

In recent years, with the rapid advancement of large language models (LLMs), role-playing language agents (RPLAs) have emerged as a prominent research focus at the intersection of natural language processing (NLP) and human-computer…

Computation and Language · Computer Science 2026-01-16 Ye Wang , Jiaxing Chen , Hongjiang Xiao

Large Language Models (LLMs) have shown great ability in solving traditional natural language tasks and elementary reasoning tasks with appropriate prompting techniques. However, their ability is still limited in solving complicated science…

Computation and Language · Computer Science 2024-04-30 Pei Chen , Boran Han , Shuai Zhang

This report investigates approaches for prompting a tool-augmented large language model (LLM) to act as a role-playing dialogue agent in the API track of the Commonsense Persona-grounded Dialogue Challenge (CPDC) 2025. In this setting,…

Computation and Language · Computer Science 2025-10-14 Saksorn Ruangtanusak , Pittawat Taveekitworachai , Kunat Pipatanakul

The application of role-playing large language models (LLMs) is rapidly expanding in both academic and commercial domains, driving an increasing demand for high-precision role-playing models. Simultaneously, the rapid advancement of…

Computation and Language · Computer Science 2025-07-23 Xiachong Feng , Longxu Dou , Lingpeng Kong

Machine reasoning has made great progress in recent years owing to large language models (LLMs). In the clinical domain, however, most NLP-driven projects mainly focus on clinical classification or reading comprehension, and under-explore…

Computation and Language · Computer Science 2024-05-13 Taeyoon Kwon , Kai Tzu-iunn Ong , Dongjin Kang , Seungjun Moon , Jeong Ryong Lee , Dosik Hwang , Yongsik Sim , Beomseok Sohn , Dongha Lee , Jinyoung Yeo

Background: Despite the current ubiquity of Large Language Models (LLMs) across the medical domain, there is a surprising lack of studies which address their reasoning behaviour. We emphasise the importance of understanding reasoning…

Computation and Language · Computer Science 2025-07-29 Shamus Sim , Tyrone Chen

Modern large language models (LLMs) exhibit a remarkable capacity for role-playing, enabling them to embody not only human characters but also non-human entities. This versatility allows them to simulate complex human-like interactions and…

Computation and Language · Computer Science 2024-03-15 Aobo Kong , Shiwan Zhao , Hao Chen , Qicheng Li , Yong Qin , Ruiqi Sun , Xin Zhou , Enzhi Wang , Xiaohang Dong
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