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We introduce MedAgentGym, a scalable and interactive training environment designed to enhance coding-based biomedical reasoning capabilities in large language model (LLM) agents. MedAgentGym comprises 72,413 task instances across 129…

Though Large Vision-Language Models (LVLMs) are being actively explored in medicine, their ability to conduct complex real-world telemedicine consultations combining accurate diagnosis with professional dialogue remains underexplored. This…

Human-Computer Interaction · Computer Science 2025-11-12 Ivan Sviridov , Amina Miftakhova , Artemiy Tereshchenko , Galina Zubkova , Pavel Blinov , Andrey Savchenko

Clinical decision-making is a dynamic, interactive, and cyclic process where doctors have to repeatedly decide on which clinical action to perform and consider newly uncovered information for diagnosis and treatment. Large Language Models…

Computation and Language · Computer Science 2026-03-03 David Bani-Harouni , Chantal Pellegrini , Ege Özsoy , Nassir Navab , Matthias Keicher

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

Advancements in large language models (LLMs) allow them to address diverse questions using human-like interfaces. Still, limitations in their training prevent them from answering accurately in scenarios that could benefit from multiple…

Artificial Intelligence · Computer Science 2025-04-09 Yoshitaka Inoue , Tianci Song , Xinling Wang , Augustin Luna , Tianfan Fu

The rise of Large Language Models (LLMs) has enabled the development of specialized AI agents with domain-specific reasoning and interaction capabilities, particularly in healthcare. While recent frameworks simulate medical decision-making,…

Artificial Intelligence · Computer Science 2025-07-04 Tianqi Shang , Weiqing He , Charles Zheng , Lingyao Li , Li Shen , Bingxin Zhao

Large Language Models (LLMs) as clinical agents require careful behavioral adaptation. While adept at reactive tasks (e.g., diagnosis reasoning), LLMs often struggle with proactive engagement, like unprompted identification of critical…

Large language models have emerged as a promising approach towards achieving general-purpose AI agents. The thriving open-source LLM community has greatly accelerated the development of agents that support human-machine dialogue interaction…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Zhenfei Yin , Jiong Wang , Jianjian Cao , Zhelun Shi , Dingning Liu , Mukai Li , Lu Sheng , Lei Bai , Xiaoshui Huang , Zhiyong Wang , Jing Shao , Wanli Ouyang

Recent large language models (LLMs) have demonstrated significant advancements, particularly in their ability to serve as agents thereby surpassing their traditional role as chatbots. These agents can leverage their planning and tool…

Machine Learning · Computer Science 2025-02-13 Yixing Jiang , Kameron C. Black , Gloria Geng , Danny Park , James Zou , Andrew Y. Ng , Jonathan H. Chen

Artificial intelligence has significantly advanced healthcare, particularly through large language models (LLMs) that excel in medical question answering benchmarks. However, their real-world clinical application remains limited due to the…

Computation and Language · Computer Science 2024-07-01 Zhihao Fan , Jialong Tang , Wei Chen , Siyuan Wang , Zhongyu Wei , Jun Xi , Fei Huang , Jingren Zhou

Long-horizon interactions between users and LLM-based assistants necessitate effective memory management, yet current approaches face challenges in training and evaluation of memory. Existing memory benchmarks rely on static, off-policy…

Computation and Language · Computer Science 2026-03-03 Cheng Jiayang , Dongyu Ru , Lin Qiu , Yiyang Li , Xuezhi Cao , Yangqiu Song , Xunliang Cai

As Large Language Models (LLMs) are increasingly deployed in highly specialized vertical domains, the evaluation of their domain-specific performance becomes critical. However, existing evaluations for vertical domains typically rely on the…

Artificial Intelligence · Computer Science 2025-09-26 Wanying Wang , Zeyu Ma , Xuhong Wang , Yangchun Zhang , Pengfei Liu , Mingang Chen

Standard single-turn, static benchmarks fall short in evaluating the nuanced capabilities of Large Language Models (LLMs) on complex tasks such as software engineering. In this work, we propose a novel interactive evaluation framework that…

Artificial Intelligence · Computer Science 2025-08-27 Dimitrios Rontogiannis , Maxime Peyrard , Nicolas Baldwin , Martin Josifoski , Robert West , Dimitrios Gunopulos

Training mental health clinicians to conduct standardized clinical assessments is challenging due to a lack of scalable, realistic practice opportunities, which can impact data quality in clinical trials. To address this gap, we introduce a…

Human-Computer Interaction · Computer Science 2025-12-30 Veronica Bossio Botero , Vijay Yadav , Jacob Ouyang , Anzar Abbas , Michelle Worthington

Evaluating large language models (LLMs) on their ability to generate high-quality, accurate, situationally aware answers to clinical questions requires going beyond conventional benchmarks to assess how these systems behave in complex,…

Automating radiology report generation poses a dual challenge: building clinically reliable systems and designing rigorous evaluation protocols. We introduce a multi-agent reinforcement learning framework that serves as both a benchmark and…

Artificial Intelligence · Computer Science 2025-09-23 Ahmed T. Elboardy , Ghada Khoriba , Essam A. Rashed

The transition of Large Language Models (LLMs) from passive knowledge retrievers to autonomous clinical agents demands a shift in evaluation-from static accuracy to dynamic behavioral reliability. To explore this boundary in dentistry, a…

Computation and Language · Computer Science 2026-01-21 Hongyang Ma , Tiantian Gu , Huaiyuan Sun , Huilin Zhu , Yongxin Wang , Jie Li , Wubin Sun , Zeliang Lian , Yinghong Zhou , Yi Gao , Shirui Wang , Zhihui Tang

Recent advancements in medical Large Language Models (LLMs) have showcased their powerful reasoning and diagnostic capabilities. Despite their success, current unified multimodal medical LLMs face limitations in knowledge update costs,…

Computation and Language · Computer Science 2025-06-25 Yucheng Zhou , Lingran Song , Jianbing Shen

There has been a growing interest in developing learner models to enhance learning and teaching experiences in educational environments. However, existing works have primarily focused on structured environments relying on meticulously…

Machine Learning · Computer Science 2024-05-01 Bahar Radmehr , Adish Singla , Tanja Käser

Large Language Models (LLMs) are transforming artificial intelligence, enabling autonomous agents to perform diverse tasks across various domains. These agents, proficient in human-like text comprehension and generation, have the potential…

Artificial Intelligence · Computer Science 2024-04-10 Saikat Barua