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Considering the profound transformation affecting pathology practice, we aimed to develop a scalable artificial intelligence (AI) system to diagnose colorectal cancer from whole-slide images (WSI). For this, we propose a deep learning (DL)…

Cancer survival prediction from whole slide images (WSIs) is a challenging task in computational pathology due to the large size, irregular shape, and high granularity of the WSIs. These characteristics make it difficult to capture the full…

Image and Video Processing · Electrical Eng. & Systems 2025-03-05 Rustin Soraki , Huayu Wang , Joann G. Elmore , Linda Shapiro

Multi-Instance Learning (MIL) has shown impressive performance for histopathology whole slide image (WSI) analysis using bags or pseudo-bags. It involves instance sampling, feature representation, and decision-making. However, existing…

Computer Vision and Pattern Recognition · Computer Science 2024-03-14 Tingting Zheng , Kui Jiang , Hongxun Yao

Whole-slide images (WSI) in computational pathology have high resolution with gigapixel size, but are generally with sparse regions of interest, which leads to weak diagnostic relevance and data inefficiency for each area in the slide. Most…

Computer Vision and Pattern Recognition · Computer Science 2022-12-14 Boxuan Zhao , Jun Zhang , Deheng Ye , Jian Cao , Xiao Han , Qiang Fu , Wei Yang

Canine mammary carcinoma (CMC) has been used as a model to investigate the pathogenesis of human breast cancer and the same grading scheme is commonly used to assess tumor malignancy in both. One key component of this grading scheme is the…

Computer Vision and Pattern Recognition · Computer Science 2020-11-30 Marc Aubreville , Christof A. Bertram , Taryn A. Donovan , Christian Marzahl , Andreas Maier , Robert Klopfleisch

Few-shot learning presents a critical solution for cancer diagnosis in computational pathology (CPath), addressing fundamental limitations in data availability, particularly the scarcity of expert annotations and patient privacy…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Zhengrui Guo , Conghao Xiong , Jiabo Ma , Qichen Sun , Lishuang Feng , Jinzhuo Wang , Hao Chen

Saliency modeling has been an active research area in computer vision for about two decades. Existing state of the art models perform very well in predicting where people look in natural scenes. There is, however, the risk that these models…

Computer Vision and Pattern Recognition · Computer Science 2015-05-15 Ali Borji , Laurent Itti

Interaction data is widely used in multiple domains such as cognitive science, visualization, human computer interaction, and cybersecurity, among others. Applications range from cognitive analyses over user/behavior modeling, adaptation,…

Understanding the intricate workflows of cataract surgery requires modeling complex interactions between surgical tools, anatomical structures, and procedural techniques. Existing datasets primarily address isolated aspects of surgical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Felix Holm , Gözde Ünver , Ghazal Ghazaei , Nassir Navab

Pathology image segmentation is crucial in computational pathology for analyzing histological features relevant to cancer diagnosis and prognosis. However, current methods face major challenges in clinical applications due to limited…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Zhixuan Chen , Junlin Hou , Liqi Lin , Yihui Wang , Yequan Bie , Xi Wang , Yanning Zhou , Ronald Cheong Kin Chan , Hao Chen

Recent advances in whole slide imaging (WSI) technology have led to the development of a myriad of computer vision and artificial intelligence (AI) based diagnostic, prognostic, and predictive algorithms. Computational Pathology (CPath)…

Brain-computer interfaces (BCIs) have opened new platforms for human-computer interaction, medical diagnostics, and neurorehabilitation. Wearable BCI systems, which typically employ non-invasive electrodes for portable monitoring, hold…

Human-Computer Interaction · Computer Science 2026-04-14 Haoxian Liu , Hengle Jiang , Lanxuan Hong , Xiaomin Ouyang

The aggressiveness of prostate cancer, the most common cancer in men worldwide, is primarily assessed based on histopathological data using the Gleason scoring system. While artificial intelligence (AI) has shown promise in accurately…

Standard of care diagnostic procedure for suspected skin cancer is microscopic examination of hematoxylin \& eosin stained tissue by a pathologist. Areas of high inter-pathologist discordance and rising biopsy rates necessitate higher…

Automatic outlining of different tissue types in digitized histological specimen provides a basis for follow-up analyses and can potentially guide subsequent medical decisions. The immense size of whole-slide-images (WSI), however, poses a…

For prostate cancer patients, the Gleason score is one of the most important prognostic factors, potentially determining treatment independent of the stage. However, Gleason scoring is based on subjective microscopic examination of tumor…

Whole Slide Image (WSI) classification is often formulated as a Multiple Instance Learning (MIL) problem. Recently, Vision-Language Models (VLMs) have demonstrated remarkable performance in WSI classification. However, existing methods…

Computer Vision and Pattern Recognition · Computer Science 2024-04-08 Hao Li , Ying Chen , Yifei Chen , Wenxian Yang , Bowen Ding , Yuchen Han , Liansheng Wang , Rongshan Yu

As advances in large language models (LLMs) and multimodal techniques continue to mature, the development of general-purpose multimodal large language models (MLLMs) has surged, offering significant applications in interpreting natural…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Yuxuan Sun , Chenglu Zhu , Sunyi Zheng , Kai Zhang , Lin Sun , Zhongyi Shui , Yunlong Zhang , Honglin Li , Lin Yang

Representation learning for Whole Slide Images (WSIs) is pivotal in developing image-based systems to achieve higher precision in diagnostic pathology. We propose a two-stage framework for WSI representation learning. We sample relevant…

Image and Video Processing · Electrical Eng. & Systems 2020-04-20 Mohammed Adnan , Shivam Kalra , Hamid R. Tizhoosh

Pathology is the study of microscopic inspection of tissue, and a pathology diagnosis is often the medical gold standard to diagnose disease. Pathology images provide a unique challenge for computer-vision-based analysis: a single pathology…