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The nature of clinical data makes it difficult to quickly select, tune and apply machine learning algorithms to clinical prognosis. As a result, a lot of time is spent searching for the most appropriate machine learning algorithms…

Machine Learning · Computer Science 2015-04-21 Kwetishe Joro Danjuma

Recent advances in genomic sequencing technology have resulted in an abundance of genome sequence data. Despite the progress in interpreting those data, there remains a broad scope for their translation into clinical and societal benefits.…

Genomics · Quantitative Biology 2021-12-13 Abhinav Jain , Greg Slabaugh , Deepti Gurdasani

In this work, we investigate the importance of ethnicity in colorectal cancer survivability prediction using machine learning techniques and the SEER cancer incidence database. We compare model performances for 2-year survivability…

Machine Learning · Computer Science 2019-01-15 Samuel Li , Talayeh Razzaghi

We proposed a fully automatic workflow for glioblastoma (GBM) survival prediction using deep learning (DL) methods. 285 glioma (210 GBM, 75 low-grade glioma) patients were included. 163 of the GBM patients had overall survival (OS) data.…

Medical Physics · Physics 2021-07-07 Jie Fu , Kamal Singhrao , Xinran Zhong , Yu Gao , Sharon Qi , Yingli Yang , Dan Ruan , John H Lewis

Multimodal deep learning has improved prognostic accuracy for brain tumours by integrating histopathology and genomic data, yet the contribution of volumetric MRI within unified survival frameworks remains unexplored. This pilot study…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Iain Swift , JingHua Ye

Prognostic information at diagnosis has important implications for cancer treatment and monitoring. Although cancer staging, histopathological assessment, molecular features, and clinical variables can provide useful prognostic insights,…

Computer-aided cancer survival risk prediction plays an important role in the timely treatment of patients. This is a challenging weakly supervised ordinal regression task associated with multiple clinical factors involved such as…

Machine Learning · Computer Science 2024-09-05 Zekang Yang , Hong Liu , Xiangdong Wang

We explore whether survival model performance in underrepresented high- and low-risk subgroups - regions of the prognostic spectrum where clinical decisions are most consequential - can be improved through targeted restructuring of the…

Multimodal deep learning for cancer prognosis is commonly assumed to benefit from synergistic cross-modal interactions, yet this assumption has not been directly tested in survival prediction settings. This work adapts InterSHAP, a Shapley…

Machine Learning · Computer Science 2026-04-15 Iain Swift , JingHua Ye , Ruairi O'Reilly

Predicting the likelihood of survival is of paramount importance for individuals diagnosed with cancer as it provides invaluable information regarding prognosis at an early stage. This knowledge enables the formulation of effective…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Numan Saeed , Muhammad Ridzuan , Fadillah Adamsyah Maani , Hussain Alasmawi , Karthik Nandakumar , Mohammad Yaqub

We tested 14 very different classification algorithms (random forest, gradient boosting machines, SVM - linear, polynomial, and RBF - 1-hidden-layer neural nets, extreme learning machines, k-nearest neighbors and a bagging of knn, naive…

Machine Learning · Computer Science 2016-06-06 Jacques Wainer

Among the various types of cyberattacks, identifying zero-day attacks is problematic because they are unknown to security systems as their pattern and characteristics do not match known blacklisted attacks. There are many Machine Learning…

Cryptography and Security · Computer Science 2025-12-09 Zahra Lotfi , Mostafa Lotfi

In this paper, we predict conditional survival functions through a combined regression strategy. We take weak learners as different random survival trees. We propose to maximize concordance in the right-censored set up to find the optimal…

Machine Learning · Statistics 2022-10-12 Rahul Goswami , Arabin Kumar Dey

In this paper we compare traditional machine learning and deep learning models trained on a malware dataset when subjected to adversarial attack based on label-flipping. Specifically, we investigate the robustness of Support Vector Machines…

Machine Learning · Computer Science 2025-01-23 Sarvagya Bhargava , Mark Stamp

Lung cancer is the leading cause of cancer mortality worldwide, and non-invasive methods for detecting key mutations and staging are essential for improving patient outcomes. Here, we compare the performance of two machine learning models -…

Image and Video Processing · Electrical Eng. & Systems 2025-05-29 Yiheng Li , Francisco Carrillo-Perez , Mohammed Alawad , Olivier Gevaert

The Cox Proportional Hazards (PH) model is widely used in survival analysis. Recently, artificial neural network (ANN)-based Cox-PH models have been developed. However, training these Cox models with high-dimensional features typically…

Machine Learning · Computer Science 2026-01-29 Anchen Sun , Zhibin Chen , Xiaodong Cai

This paper primarily addresses a dataset relating to cellular, chemical and physical conditions of patients gathered at the time they are operated upon to remove colorectal tumours. This data provides a unique insight into the biochemical…

Machine Learning · Computer Science 2016-11-17 Christopher Roadknight , Durga Suryanarayanan , Uwe Aickelin , John Scholefield , Lindy Durrant

Multi-omics data, that is, datasets containing different types of high-dimensional molecular variables (often in addition to classical clinical variables), are increasingly generated for the investigation of various diseases. Nevertheless,…

Machine Learning · Statistics 2020-12-22 Moritz Herrmann , Philipp Probst , Roman Hornung , Vindi Jurinovic , Anne-Laure Boulesteix

This paper explores machine learning (ML) models for classifying lung cancer levels to improve diagnostic accuracy and prognosis. Through parameter tuning and rigorous evaluation, we assess various ML algorithms. Techniques like minimum…

Artificial Intelligence · Computer Science 2024-12-05 Mohsen Asghari Ilani , Saba Moftakhar Tehran , Ashkan Kavei , Hamed Alizadegan

Motivation: Identification of genomic, molecular and clinical markers prognostic of patient survival is important for developing personalized disease prevention, diagnostic and treatment approaches. Modern omics technologies have made it…

Applications · Statistics 2024-03-05 Zhi Zhao , John Zobolas , Manuela Zucknick , Tero Aittokallio
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