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Cancer remains a leading global health challenge and a major cause of mortality. This study leverages machine learning (ML) to predict the survivability of cancer patients with metastatic patterns using the comprehensive MSK-MET dataset,…

Quantitative Methods · Quantitative Biology 2025-04-10 Polycarp Nalela , Deepthi Rao , Praveen Rao

Survival analysis is a statistical framework for modeling time-to-event data, particularly valuable in healthcare for predicting outcomes like patient discharge or recurrence. This study implements and compares several survival models -…

The choice of the most effective treatment may eventually be influenced by breast cancer survival prediction. To predict the chances of a patient surviving, a variety of techniques were employed, such as statistical, machine learning, and…

Machine Learning · Computer Science 2023-04-18 Khaoula Chtouki , Maryem Rhanoui , Mounia Mikram , Kamelia Amazian , Siham Yousfi

Survival analysis is essential for studying time-to-event outcomes and providing a dynamic understanding of the probability of an event occurring over time. Various survival analysis techniques, from traditional statistical models to…

Machine Learning · Computer Science 2024-03-13 Ziwen Wang , Jin Wee Lee , Tanujit Chakraborty , Yilin Ning , Mingxuan Liu , Feng Xie , Marcus Eng Hock Ong , Nan Liu

We propose predictive models that estimate GBM patients' health status of one-year after treatments (Classification task), predict the long-term prognosis of GBM patients at an individual level (Survival task). We used total of 467 GBM…

Machine Learning · Computer Science 2021-09-10 Yeseul Kim , Kyung Hwan Kim , Junyoung Park , Hong In Yoon , Wonmo Sung

Radiomic models have been shown to outperform clinical data for outcome prediction in glioblastoma (GBM). However, clinical implementation is limited by lack of parameters standardization. We aimed to compare nine machine learning…

Clinical risk prediction models often underperform in real-world settings due to poor calibration, limited transportability, and subgroup disparities. These challenges are amplified in high-dimensional multimodal cancer datasets…

Machine Learning · Computer Science 2026-02-26 Toktam Khatibi

Objective: This study explores a semi-supervised learning (SSL), pseudo-labeled strategy using diverse datasets to enhance lung cancer (LCa) survival predictions, analyzing Handcrafted and Deep Radiomic Features (HRF/DRF) from PET/CT scans…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Mohammad R. Salmanpour , Arman Gorji , Amin Mousavi , Ali Fathi Jouzdani , Nima Sanati , Mehdi Maghsudi , Bonnie Leung , Cheryl Ho , Ren Yuan , Arman Rahmim

This paper compares the performances of three supervised machine learning algorithms in terms of predictive ability and model interpretation on structured or tabular data. The algorithms considered were scikit-learn implementations of…

Machine Learning · Statistics 2022-05-06 Alice J. Liu , Arpita Mukherjee , Linwei Hu , Jie Chen , Vijayan N. Nair

Prediction of Overall Survival (OS) of brain cancer patients from multi-modal MRI is a challenging field of research. Most of the existing literature on survival prediction is based on Radiomic features, which does not consider either…

Quantitative Methods · Quantitative Biology 2021-09-08 Subhashis Banerjee , Sushmita Mitra , Lawrence O. Hall

Objective: In randomized clinical trials, prediction models can be used to explore the relationships between patients' variables (e.g., clinical, pathological, or lifestyle variables, and also biomarker or genomic data) and treatment effect…

Quantitative Methods · Quantitative Biology 2026-02-03 Elvire Roblin , Paul-Henry Cournède , Stefan Michiels

Survival regression is used to estimate the relation between time-to-event and feature variables, and is important in application domains such as medicine, marketing, risk management and sales management. Nonlinear tree based machine…

Machine Learning · Computer Science 2021-08-24 Avinash Barnwal , Hyunsu Cho , Toby Dylan Hocking

Objectives: Lung cancer poses a significant global health challenge, necessitating improved prognostic methods for personalized treatment. This study introduces a censor-aware semi-supervised learning (SSL) framework that integrates…

Medical Physics · Physics 2025-06-16 Arman Gorji , Ali Fathi Jouzdani , Nima Sanati , Ren Yuan , Arman Rahmim , Mohammad R. Salmanpour

Lung cancer remains one of the leading causes of cancer-related mortality, yet most survival models rely only on baseline factors and overlook posttreatment variables that reflect disease progression. To address this gap, we applied Cox…

Applications · Statistics 2025-10-03 Varun Vishwanathan Nair , Victor Miranda Soberanis

Multimodal machine learning integrating histopathology and molecular data shows promise for cancer prognostication. We systematically reviewed studies combining whole slide images (WSIs) and high-throughput omics to predict overall…

Quantitative Methods · Quantitative Biology 2025-07-30 Charlotte Jennings , Andrew Broad , Lucy Godson , Emily Clarke , David Westhead , Darren Treanor

Predictive modelling is vital to guide preventive efforts. Whilst large-scale prospective cohort studies and a diverse toolkit of available machine learning (ML) algorithms have facilitated such survival task efforts, choosing the…

In this paper we utilize a survival analysis methodology incorporating Bayesian additive regression trees to account for nonlinear and additive covariate effects. We compare the performance of Bayesian additive regression trees, Cox…

Applications · Statistics 2019-11-05 Satabdi Saha , Duchwan Ryu , Nader Ebrahimi

We study multimodal survival analysis integrating clinical text, tabular covariates, and genomic profiles using locally deployable large language models (LLMs). As many institutions face tight computational and privacy constraints, this…

Machine Learning · Computer Science 2026-03-24 Moritz Gögl , Christopher Yau

Background and objective Risk prediction models aim at identifying people at higher risk of developing a target disease. Feature selection is particularly important to improve the prediction model performance avoiding overfitting and to…

Machine Learning · Computer Science 2024-02-09 N. Cueto-López , M. T. García-Ordás , V. Dávila-Batista , V. Moreno , N. Aragonés , R. Alaiz-Rodríguez

Background: This research aims to improve glioblastoma survival prediction by integrating MR images, clinical and molecular-pathologic data in a transformer-based deep learning model, addressing data heterogeneity and performance…

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