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Brain lesions, including stroke and tumours, have a high degree of variability in terms of location, size, intensity and form, making automatic segmentation difficult. We propose an improvement to existing segmentation methods by exploiting…

Image and Video Processing · Electrical Eng. & Systems 2019-07-22 Kevin Raina , Uladzimir Yahorau , Tanya Schmah

Unsupervised anomaly detection (UAD) in brain imaging is crucial for identifying pathologies without the need for labeled data. However, accurately localizing anomalies remains challenging due to the intricate structure of brain anatomy and…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Farzad Beizaee , Sina Hajimiri , Ismail Ben Ayed , Gregory Lodygensky , Christian Desrosiers , Jose Dolz

In real-world clinical practice, overlooking unanticipated findings can result in serious consequences. However, supervised learning, which is the foundation for the current success of deep learning, only encourages models to identify…

Accurate and generalisable segmentation of stroke lesions from magnetic resonance imaging (MRI) is essential for advancing clinical research, prognostic modelling, and personalised interventions. Although deep learning has improved…

Quantitative Methods · Quantitative Biology 2026-02-11 Tammar Truzman , Matthew A. Lambon Ralph , Ajay D. Halai

Magnetic resonance imaging (MRI) is a crucial tool to identify brain abnormalities in a wide range of neurological disorders. In focal epilepsy MRI is used to identify structural cerebral abnormalities. For covert lesions, machine learning…

Brain lesions are abnormalities or injuries in brain tissue that are often detectable using magnetic resonance imaging (MRI), which reveals structural changes in the affected areas. This broad definition of brain lesions includes areas of…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Omar Zamzam , Haleh Akrami , Anand Joshi , Richard Leahy

Lesion detection in brain Magnetic Resonance Images (MRI) remains a challenging task. State-of-the-art approaches are mostly based on supervised learning making use of large annotated datasets. Human beings, on the other hand, even…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Xiaoran Chen , Ender Konukoglu

Accurate stroke lesion segmentation plays a pivotal role in stroke rehabilitation research, to provide lesion shape and size information which can be used for quantification of the extent of the stroke and to assess treatment efficacy.…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Jiayu Huo , Liyun Chen , Yang Liu , Maxence Boels , Alejandro Granados , Sebastien Ourselin , Rachel Sparks

Lesions that appear hyperintense in both Fluid Attenuated Inversion Recovery (FLAIR) and T2-weighted magnetic resonance images (MRIs) of the human brain are common in the brains of the elderly population and may be caused by ischemia or…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Hans E. Atlason , Askell Love , Sigurdur Sigurdsson , Vilmundur Gudnason , Lotta M. Ellingsen

Detection of various lesions in brain MRI is clinically critical, but challenging due to the diversity of lesions and variability in imaging conditions. Current unsupervised learning methods detect anomalies mainly through reconstructing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Tao Yang , Xiuying Wang , Hao Liu , Guanzhong Gong , Lian-Ming Wu , Yu-Ping Wang , Lisheng Wang

Brain stroke has become a significant burden on global health and thus we need remedies and prevention strategies to overcome this challenge. For this, the immediate identification of stroke and risk stratification is the primary task for…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Prantik Deb , Lalith Bharadwaj Baru , Kamalaker Dadi , Bapi Raju S

Background Atrial fibrillation is often missed by traditional intermittent electrocardiogram monitoring after ischemic stroke due to its paroxysmal and asymptomatic nature. The knowledge of the unique characteristics of the population with…

Neurons and Cognition · Quantitative Biology 2023-05-25 Yiming Chen , Sihui Wang , Dong Xu

The accurate understanding of ischemic stroke lesions is critical for efficient therapy and prognosis of stroke patients. Magnetic resonance imaging (MRI) is sensitive to acute ischemic stroke and is a common diagnostic method for stroke.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 R. P. Chowdhury , T. Rahman

Background: The brain's functional network constantly adapts to external changes. However, the mechanisms underlying this dynamic adaptive behavior in stroke patients with motor injuries and its role in post-stroke motor recovery remain…

Neurons and Cognition · Quantitative Biology 2024-01-18 Kaichao Wu , Beth Jelfs , Katrina Neville , Qiang Fang

Machine learning offers great potential for automated prediction of post-stroke symptoms and their response to rehabilitation. Major challenges for this endeavour include the very high dimensionality of neuroimaging data, the relatively…

Artificial Intelligence · Computer Science 2023-10-31 Adam White , Margarita Saranti , Artur d'Avila Garcez , Thomas M. H. Hope , Cathy J. Price , Howard Bowman

When the blood supply to the brain is obstructed by a clot, oxygen delivery to brain tissues becomes insufficient, leading to cellular necrosis. In healthcare settings, accurately identifying and delineating ischemic lesion boundaries is…

Image and Video Processing · Electrical Eng. & Systems 2026-05-22 Sayed Amir Mousavi Mobarakeh

This study addresses the challenge of predicting post-stroke rigidity by emphasizing feature interactions through graph-based explainable AI. Post-stroke rigidity, characterized by increased muscle tone and stiffness, significantly affects…

Unsupervised anomaly segmentation approaches to pathology segmentation train a model on images of healthy subjects, that they define as the 'normal' data distribution. At inference, they aim to segment any pathologies in new images as…

Image and Video Processing · Electrical Eng. & Systems 2024-06-06 Ziyun Liang , Xiaoqing Guo , J. Alison Noble , Konstantinos Kamnitsas

There are considerable interests in automatic stroke lesion segmentation on magnetic resonance (MR) images in the medical imaging field, as stroke is an important cerebrovascular disease. Although deep learning-based models have been…

Image and Video Processing · Electrical Eng. & Systems 2023-03-07 Weiyi Yu , Zhizhong Huang , Junping Zhang , Hongming Shan

Oversight in medical images is a crucial problem, and timely reporting of medical images is desired. Therefore, an all-purpose anomaly detection method that can detect virtually all types of lesions/diseases in a given image is strongly…

Image and Video Processing · Electrical Eng. & Systems 2020-10-21 H. Shibata , S. Hanaoka , Y. Nomura , T. Nakao , I. Sato , D. Sato , N. Hayashi , O. Abe
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