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Related papers: META-RAG: Meta-Analysis-Inspired Evidence-Re-Ranki…

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Evidence-based medicine (EBM) plays a crucial role in the application of large language models (LLMs) in healthcare, as it provides reliable support for medical decision-making processes. Although it benefits from current…

Computation and Language · Computer Science 2025-03-24 Chengfeng Dou , Ying Zhang , Zhi Jin , Wenpin Jiao , Haiyan Zhao , Yongqiang Zhao , Zhengwei Tao

Retrieval-augmented Generation (RAG) has demonstrated potential in enhancing medical question-answering systems through the integration of large language models (LLMs) with external medical literature. LLMs can retrieve relevant medical…

Computation and Language · Computer Science 2025-10-29 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Haochun Wang , Bin Qin

Large language models (LLMs) are transforming the landscape of medicine, yet two fundamental challenges persist: keeping up with rapidly evolving medical knowledge and providing verifiable, evidence-grounded reasoning. Retrieval-augmented…

Evidence-based medicine (EBM) research has always been of paramount importance. It is important to find appropriate medical theoretical support for the needs from physicians or patients to reduce the occurrence of medical accidents. This…

Computation and Language · Computer Science 2025-10-29 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Bin Qin

When addressing professional questions in the biomedical domain, humans typically acquire multiple pieces of information as evidence and engage in multifaceted analysis to provide high-quality answers. Current LLM-based question answering…

Computation and Language · Computer Science 2025-09-03 Chang Zong , Jian Wan , Siliang Tang , Lei Zhang

Large Language Models (LLMs) have exhibited remarkable capabilities in clinical scenarios. Despite their potential, existing works face challenges when applying LLMs to medical settings. Strategies relying on training with medical datasets…

Computation and Language · Computer Science 2025-10-10 Keer Lu , Zheng Liang , Da Pan , Shusen Zhang , Guosheng Dong , Zhonghai Wu , Huang Leng , Bin Cui , Wentao Zhang

The rapid growth of medical knowledge and increasing complexity of clinical practice pose challenges. In this context, large language models (LLMs) have demonstrated value; however, inherent limitations remain. Retrieval-augmented…

Retrieval-augmented generation (RAG) has emerged as a promising approach to enhance the performance of large language models (LLMs) in knowledge-intensive tasks such as those from medical domain. However, the sensitive nature of the medical…

Computation and Language · Computer Science 2024-11-15 Nghia Trung Ngo , Chien Van Nguyen , Franck Dernoncourt , Thien Huu Nguyen

Large language models (LLMs) excel in question-answering (QA) tasks, and retrieval-augmented generation (RAG) enhances their precision by incorporating external evidence from diverse sources like web pages, databases, and knowledge graphs.…

Information Retrieval · Computer Science 2025-04-10 Yikuan Xia , Jiazun Chen , Yirui Zhan , Suifeng Zhao , Weipeng Jiang , Chaorui Zhang , Wei Han , Bo Bai , Jun Gao

Large language models (LLMs) have shown promise in medical question answering but often struggle with hallucinations and shallow reasoning, particularly in tasks requiring nuanced clinical understanding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2025-08-25 Ziyu Wang , Elahe Khatibi , Amir M. Rahmani

Retrieval augmented generation (RAG) systems provide a method for factually grounding the responses of a Large Language Model (LLM) by providing retrieved evidence, or context, as support. Guided by this context, RAG systems can reduce…

Information Retrieval · Computer Science 2025-09-05 Shakiba Amirshahi , Amin Bigdeli , Charles L. A. Clarke , Amira Ghenai

Biomedical question answering (QA) requires accurate interpretation of complex medical knowledge. Large language models (LLMs) have shown promising capabilities in this domain, with retrieval-augmented generation (RAG) systems enhancing…

Computation and Language · Computer Science 2025-10-21 Yingpeng Ning , Yuanyuan Sun , Ling Luo , Yanhua Wang , Yuchen Pan , Hongfei Lin

While Retrieval-Augmented Generation (RAG) has been swiftly adopted in scientific and clinical QA systems, a comprehensive evaluation benchmark in the medical domain is lacking. To address this gap, we introduce the Medical…

Computation and Language · Computer Science 2026-02-12 Liz Li , Wei Zhu

Large language models (LLMs) incorporated with Retrieval-Augmented Generation (RAG) have demonstrated powerful capabilities in generating counterspeech against misinformation. However, current studies rely on limited evidence and offer less…

Computation and Language · Computer Science 2025-09-16 Anirban Saha Anik , Xiaoying Song , Elliott Wang , Bryan Wang , Bengisu Yarimbas , Lingzi Hong

The retrieval-augmented generation (RAG) enables retrieval of relevant information from an external knowledge source and allows large language models (LLMs) to answer queries over previously unseen document collections. However, it was…

Computation and Language · Computer Science 2025-04-03 Mykhailo Poliakov , Nadiya Shvai

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

Computation and Language · Computer Science 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov

Evidence-based medicine (EBM) is at the forefront of modern healthcare, emphasizing the use of the best available scientific evidence to guide clinical decisions. Due to the sheer volume and rapid growth of medical literature and the high…

Computation and Language · Computer Science 2025-05-29 Zihan Xu , Haotian Ma , Gongbo Zhang , Yihao Ding , Chunhua Weng , Yifan Peng

Retrieval Augmented Generation (RAG) complements the knowledge of Large Language Models (LLMs) by leveraging external information to enhance response accuracy for queries. This approach is widely applied in several fields by taking its…

Large Language Models (LLMs), although powerful in general domains, often perform poorly on domain-specific tasks such as medical question answering (QA). In addition, LLMs tend to function as "black-boxes", making it challenging to modify…

Computation and Language · Computer Science 2024-08-19 Yucheng Shi , Shaochen Xu , Tianze Yang , Zhengliang Liu , Tianming Liu , Quanzheng Li , Xiang Li , Ninghao Liu

Multimodal Retrieval-Augmented Generation (MRAG) addresses key limitations of Multimodal Large Language Models (MLLMs), such as hallucination and outdated knowledge. However, current MRAG systems struggle to distinguish whether retrieved…

Computation and Language · Computer Science 2026-05-01 Xihang Wang , Zihan Wang , Chengkai Huang , Quan Z. Sheng , Lina Yao
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