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Evidence-based medicine (EBM) holds a crucial role in clinical application. Given suitable medical articles, doctors effectively reduce the incidence of misdiagnoses. Researchers find it efficient to use large language models (LLMs)…

Computation and Language · Computer Science 2025-11-07 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Haochun Wang , Bing Qin

Large language models (LLMs) are transforming the landscape of medicine, yet two fundamental challenges persist: keeping up with rapidly evolving medical knowledge and providing verifiable, evidence-grounded reasoning. Retrieval-augmented…

Retrieval-augmented generation (RAG) has emerged as a promising approach to enhance the performance of large language models (LLMs) in knowledge-intensive tasks such as those from medical domain. However, the sensitive nature of the medical…

Computation and Language · Computer Science 2024-11-15 Nghia Trung Ngo , Chien Van Nguyen , Franck Dernoncourt , Thien Huu Nguyen

Retrieval augmented generation (RAG) systems provide a method for factually grounding the responses of a Large Language Model (LLM) by providing retrieved evidence, or context, as support. Guided by this context, RAG systems can reduce…

Information Retrieval · Computer Science 2025-09-05 Shakiba Amirshahi , Amin Bigdeli , Charles L. A. Clarke , Amira Ghenai

Safe and trustworthy use of Large Language Models (LLM) in the processing of healthcare documents and scientific papers could substantially help clinicians, scientists and policymakers in overcoming information overload and focusing on the…

Retrieval-Augmented Generation (RAG) is an effective approach to enhance the factual accuracy of large language models (LLMs) by retrieving information from external databases, which are typically composed of diverse sources, to supplement…

Machine Learning · Computer Science 2025-10-15 Jeongyeon Hwang , Junyoung Park , Hyejin Park , Dongwoo Kim , Sangdon Park , Jungseul Ok

Retrieval-Augmented Generation (RAG) is a powerful approach that enables large language models (LLMs) to incorporate external knowledge. However, evaluating the effectiveness of RAG systems in specialized scenarios remains challenging due…

Computation and Language · Computer Science 2025-03-05 Kunlun Zhu , Yifan Luo , Dingling Xu , Yukun Yan , Zhenghao Liu , Shi Yu , Ruobing Wang , Shuo Wang , Yishan Li , Nan Zhang , Xu Han , Zhiyuan Liu , Maosong Sun

Multimodal Retrieval-Augmented Generation (MRAG) enhances large language models (LLMs) by integrating multimodal data (text, images, videos) into retrieval and generation processes, overcoming the limitations of text-only…

Information Retrieval · Computer Science 2025-04-15 Lang Mei , Siyu Mo , Zhihan Yang , Chong Chen

The recent emergence of Medical Large Vision Language Models (Med-LVLMs) has enhanced medical diagnosis. However, current Med-LVLMs frequently encounter factual issues, often generating responses that do not align with established medical…

Machine Learning · Computer Science 2024-10-18 Peng Xia , Kangyu Zhu , Haoran Li , Hongtu Zhu , Yun Li , Gang Li , Linjun Zhang , Huaxiu Yao

Medical large vision-language Models (Med-LVLMs) have shown promise in clinical applications but suffer from factual inaccuracies and unreliable outputs, posing risks in real-world diagnostics. While RAG has emerged as a potential solution,…

Computation and Language · Computer Science 2026-05-05 Zhe Chen , Yusheng Liao , Zhiyuan Zhu , Haolin Li , Hongcheng Liu , Yanfeng Wang , Yu Wang

Retrieval Augmented Generation (RAG) complements the knowledge of Large Language Models (LLMs) by leveraging external information to enhance response accuracy for queries. This approach is widely applied in several fields by taking its…

Despite the potential of Large Language Models (LLMs) in medicine, they may generate responses lacking supporting evidence or based on hallucinated evidence. While Retrieval Augment Generation (RAG) is popular to address this issue, few…

Large language models (LLMs) have become a disruptive force in the industry, introducing unprecedented capabilities in natural language processing, logical reasoning and so on. However, the challenges of knowledge updates and hallucination…

Machine Learning · Computer Science 2025-04-22 Chunjing Gan , Dan Yang , Binbin Hu , Ziqi Liu , Yue Shen , Zhiqiang Zhang , Jian Wang , Jun Zhou

Artificial Intelligence (AI) has demonstrated significant potential in healthcare, particularly in disease diagnosis and treatment planning. Recent progress in Medical Large Vision-Language Models (Med-LVLMs) has opened up new possibilities…

Machine Learning · Computer Science 2025-03-04 Peng Xia , Kangyu Zhu , Haoran Li , Tianze Wang , Weijia Shi , Sheng Wang , Linjun Zhang , James Zou , Huaxiu Yao

Automated question-answering (QA) systems increasingly rely on retrieval-augmented generation (RAG) to ground large language models (LLMs) in authoritative medical knowledge, ensuring clinical accuracy and patient safety in Artificial…

Computation and Language · Computer Science 2026-03-05 Aswini Sivakumar , Vijayan Sugumaran , Yao Qiang

Recent advancements in Retrieval-Augmented Generation (RAG) have revolutionized natural language processing by integrating Large Language Models (LLMs) with external information retrieval, enabling accurate, up-to-date, and verifiable text…

Computation and Language · Computer Science 2025-04-22 Aoran Gan , Hao Yu , Kai Zhang , Qi Liu , Wenyu Yan , Zhenya Huang , Shiwei Tong , Guoping Hu

Large Language Models (LLMs) augmented with retrieval mechanisms have demonstrated significant potential in fact-checking tasks by integrating external knowledge. However, their reliability decreases when confronted with conflicting…

Computation and Language · Computer Science 2025-05-26 Ziyu Ge , Yuhao Wu , Daniel Wai Kit Chin , Roy Ka-Wei Lee , Rui Cao

The rapid growth of medical knowledge and increasing complexity of clinical practice pose challenges. In this context, large language models (LLMs) have demonstrated value; however, inherent limitations remain. Retrieval-augmented…

We present a comprehensive study of answer quality evaluation in Retrieval-Augmented Generation (RAG) applications using vRAG-Eval, a novel grading system that is designed to assess correctness, completeness, and honesty. We further map the…

Computation and Language · Computer Science 2024-11-08 Yang Wang , Alberto Garcia Hernandez , Roman Kyslyi , Nicholas Kersting

Biomedical question answering (QA) requires accurate interpretation of complex medical knowledge. Large language models (LLMs) have shown promising capabilities in this domain, with retrieval-augmented generation (RAG) systems enhancing…

Computation and Language · Computer Science 2025-10-21 Yingpeng Ning , Yuanyuan Sun , Ling Luo , Yanhua Wang , Yuchen Pan , Hongfei Lin
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