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Diffusion models are typically trained using pointwise reconstruction objectives that are agnostic to the spectral and multi-scale structure of natural signals. We propose a loss-level spectral regularization framework that augments…

Machine Learning · Computer Science 2026-03-04 Satish Chandran , Nicolas Roque dos Santos , Yunshu Wu , Greg Ver Steeg , Evangelos Papalexakis

Medical imaging applications are highly specialized in terms of human anatomy, pathology, and imaging domains. Therefore, annotated training datasets for training deep learning applications in medical imaging not only need to be highly…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Arjun Krishna , Ge Wang , Klaus Mueller

In supervised image restoration tasks, one key issue is how to obtain the aligned high-quality (HQ) and low-quality (LQ) training image pairs. Unfortunately, such HQ-LQ training pairs are hard to capture in practice, and hard to synthesize…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Tao Yang , Peiran Ren , Xuansong xie , Lei Zhang

Spectral computed tomography (CT) has a great superiority in lesion detection, tissue characterization and material decomposition. To further extend its potential clinical applications, in this work, we propose an improved tensor dictionary…

Computer Vision and Pattern Recognition · Computer Science 2018-07-25 Weiwen Wu , Yanbo Zhang , Qian Wang , Fenglin Liu , Peijun Chen , Hengyong Yu

Utilizing a low-dose CT approach significantly reduces the radiation exposure for patients, yet it introduces challenges, such as increased noise and artifacts in the resultant images, which can hinder accurate medical diagnostics.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-03 Helena Shawn , Thompson Chyrikov , Jacob Lanet , Lam-chi Chen , Jim Zhao , Christina Chajo

Coherent imaging systems, such as medical ultrasound and synthetic aperture radar (SAR), are subject to corruption from speckle due to sub-resolution scatterers. Since speckle is multiplicative in nature, the constituent image regions…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Soumee Guha , Scott T. Acton

Given the potential X-ray radiation risk to the patient, low-dose CT has attracted a considerable interest in the medical imaging field. The current main stream low-dose CT methods include vendor-specific sinogram domain filtration and…

Medical Physics · Physics 2017-12-12 Hu Chen , Yi Zhang , Mannudeep K. Kalra , Feng Lin , Yang Chen , Peixi Liao , Jiliu Zhou , Ge Wang

This paper concerns iterative reconstruction for low-dose and few-view CT by minimizing a data-fidelity term regularized with the Total Variation (TV) penalty. We propose a very fast iterative algorithm to solve this problem. The algorithm…

Medical Physics · Physics 2017-02-01 Hiroyuki Kudo , Fukashi Yamazaki , Takuya Nemoto , Keita Takaki

Nowadays, denoising diffusion probabilistic models have been adapted for many image segmentation tasks. However, existing end-to-end models have already demonstrated remarkable capabilities. Rather than using denoising diffusion…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Shi Zhenning , Dong Changsheng , Xie Xueshuo , Pan Bin , He Along , Li Tao

Patient scans from MRI often suffer from noise, which hampers the diagnostic capability of such images. As a method to mitigate such artifact, denoising is largely studied both within the medical imaging community and beyond the community…

Image and Video Processing · Electrical Eng. & Systems 2022-03-25 Hyungjin Chung , Eun Sun Lee , Jong Chul Ye

With substantial public concerns on potential cancer risks and health hazards caused by the accumulated radiation exposure in medical imaging, reducing radiation dose in X-ray based medical imaging such as Computed Tomography Perfusion…

Image and Video Processing · Electrical Eng. & Systems 2019-10-21 Peng Liu , Ruogu Fang

Cross-dose denoising for low-dose positron emission tomography (LDPET) has been proposed to address the limited generalization of models trained at a single noise level. However, neural networks trained on a specific dose level often fail…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Yichao Liu , Zongru Shao , Yueyang Teng , Junwen Guo

PET imaging is widely employed for observing biological metabolic activities within the human body. However, numerous benign conditions can cause increased uptake of radiopharmaceuticals, confounding differentiation from malignant tumors.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-31 Ran Hong , Yuxia Huang , Lei Liu , Zhonghui Wu , Bingxuan Li , Xuemei Wang , Qiegen Liu

Fluorescence molecular tomography (FMT) is a sensitive optical imaging technology widely used in biomedical research. However, the ill-posedness of the inverse problem poses a huge challenge to FMT reconstruction. Although end-to-end deep…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Peng Zhang , Qianqian Xue , Xingyu Liu , Guanglei Zhang , Wenjian Wang , Jiye Liang

The acquisition conditions for low-dose and high-dose CT images are usually different, so that the shifts in the CT numbers often occur. Accordingly, unsupervised deep learning-based approaches, which learn the target image distribution,…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Chanyong Jung , Joonhyung Lee , Sunkyoung You , Jong Chul Ye

Sparse-view Computed Tomography (CT) image reconstruction is a promising approach to reduce radiation exposure, but it inevitably leads to image degradation. Although diffusion model-based approaches are computationally expensive and suffer…

Image and Video Processing · Electrical Eng. & Systems 2024-03-15 Hanyu Chen , Zhixiu Hao , Lin Guo , Liying Xiao

Despite the recent visually-pleasing results achieved, the massive computational cost has been a long-standing flaw for diffusion probabilistic models (DPMs), which, in turn, greatly limits their applications on resource-limited platforms.…

Computer Vision and Pattern Recognition · Computer Science 2022-12-01 Xingyi Yang , Daquan Zhou , Jiashi Feng , Xinchao Wang

In this research, we propose a novel denoising diffusion model based on shortest-path modeling that optimizes residual propagation to enhance both denoising efficiency and quality. Drawing on Denoising Diffusion Implicit Models (DDIM) and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Ping Chen , Xingpeng Zhang , Zhaoxiang Liu , Huan Hu , Xiang Liu , Kai Wang , Min Wang , Yanlin Qian , Shiguo Lian

Diffusion models have demonstrated significant potential in producing high-quality images in medical image translation to aid disease diagnosis, localization, and treatment. Nevertheless, current diffusion models have limited success in…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Yunxiang Li , Hua-Chieh Shao , Xiaoxue Qian , You Zhang

Low dose computed tomography (LDCT) is desirable for both diagnostic imaging and image guided interventions. Denoisers are openly used to improve the quality of LDCT. Deep learning (DL)-based denoisers have shown state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2020-12-08 Ti Bai , Biling Wang , Dan Nguyen , Bao Wang , Bin Dong , Wenxiang Cong , Mannudeep K. Kalra , Steve Jiang