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How interpretable are the features of leading vision models? The question is increasingly pressing as these models move from research benchmarks into high-stakes deployments, yet existing methods cannot answer it reliably. We close this gap…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Julien Colin , Lore Goetschalckx , Nuria Oliver , Thomas Serre

Feature foundation models - usually vision transformers - offer rich semantic descriptors of images, useful for downstream tasks such as (interactive) segmentation and object detection. For computational efficiency these descriptors are…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Ronan Docherty , Antonis Vamvakeros , Samuel J. Cooper

Advancements in diffusion-based foundation models have improved text-to-image generation, yet most efforts have been limited to low-resolution settings. As high-resolution image synthesis becomes increasingly essential for various…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Zahra TehraniNasab , Amar Kumar , Tal Arbel

Pathological brain appearances may be so heterogeneous as to be intelligible only as anomalies, defined by their deviation from normality rather than any specific pathological characteristic. Amongst the hardest tasks in medical imaging,…

Image and Video Processing · Electrical Eng. & Systems 2021-02-24 Walter Hugo Lopez Pinaya , Petru-Daniel Tudosiu , Robert Gray , Geraint Rees , Parashkev Nachev , Sebastien Ourselin , M. Jorge Cardoso

Despite the recent success of deep learning methods at achieving new state-of-the-art accuracy for medical image segmentation, some major limitations are still restricting their deployment into clinics. One major limitation of deep…

Image and Video Processing · Electrical Eng. & Systems 2023-05-30 Lucas Fidon

As artificial intelligence systems become increasingly integrated into daily life, the field of explainability has gained significant attention. This trend is particularly driven by the complexity of modern AI models and their…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Rémi Kazmierczak , Eloïse Berthier , Goran Frehse , Gianni Franchi

Deep neural networks for medical image classification often fail to generalize consistently in clinical practice due to violations of the i.i.d. assumption and opaque decision-making. This paper examines interpretability in deep neural…

Computer Vision and Pattern Recognition · Computer Science 2025-04-09 Mohammad Hossein Najafi , Mohammad Morsali , Mohammadreza Pashanejad , Saman Soleimani Roudi , Mohammad Norouzi , Saeed Bagheri Shouraki

In the modern world, we are permanently using, leveraging, interacting with, and relying upon systems of ever higher sophistication, ranging from our cars, recommender systems in e-commerce, and networks when we go online, to integrated…

Artificial Intelligence · Computer Science 2023-06-23 Patrick Rodler

Pathology image analysis plays a pivotal role in medical diagnosis, with deep learning techniques significantly advancing diagnostic accuracy and research. While numerous studies have been conducted to address specific pathological tasks,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Dankai Liao , Sicheng Chen , Nuwa Xi , Qiaochu Xue , Jieyu Li , Lingxuan Hou , Zeyu Liu , Chang Han Low , Yufeng Wu , Yiling Liu , Yanqin Jiang , Dandan Li , Shangqing Lyu

A review of Word Embedding Models through a deconstructive approach reveals their several shortcomings and inconsistencies. These include instability of the vector representations, a distorted analogical reasoning, geometric incompatibility…

Computation and Language · Computer Science 2019-02-05 Koushik Varma Kalidindi

This paper surveys foundation models for AI-enabled biological design, focusing on recent developments in applying large-scale, self-supervised models to tasks such as protein engineering, small molecule design, and genomic sequence design.…

Artificial Intelligence · Computer Science 2025-05-20 Asher Moldwin , Amarda Shehu

Disease progression models are widely used to inform the diagnosis and treatment of many progressive diseases. However, a significant limitation of existing models is that they do not account for health disparities that can bias the…

Machine Learning · Computer Science 2025-05-01 Erica Chiang , Divya Shanmugam , Ashley N. Beecy , Gabriel Sayer , Deborah Estrin , Nikhil Garg , Emma Pierson

Foundation models (FMs) have demonstrated strong transferability across medical imaging tasks, yet their clinical utility depends critically on how pretrained representations are adapted to domain-specific data, supervision regimes, and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Karma Phuntsho , Abdullah , Kyungmi Lee , Ickjai Lee , Euijoon Ahn

In the era of foundation models and Large Language Models (LLMs), Euclidean space has been the de facto geometric setting for machine learning architectures. However, recent literature has demonstrated that this choice comes with…

Machine Learning · Computer Science 2025-11-26 Neil He , Jiahong Liu , Buze Zhang , Ngoc Bui , Ali Maatouk , Menglin Yang , Irwin King , Melanie Weber , Rex Ying

Rapid progress in computational pathology is increasingly driven by vision foundation models pretrained on vast histopathology datasets. While recent efforts have prioritized training on an ever-larger amount of patches, we take an…

The widespread adoption of large language and vision models in real-world applications has made urgent the need to address hallucinations -- instances where models produce incorrect or nonsensical outputs. These errors can propagate…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Zhengyi Ho , Siyuan Liang , Dacheng Tao

Finetuning can significantly modify the behavior of large language models, including introducing harmful or unsafe behaviors. To study these risks, researchers develop model organisms: models finetuned to exhibit specific known behaviors…

Computation and Language · Computer Science 2026-05-05 Mohammed Abu Baker , Luca Baroni , Dan Wilhelm

Patient-specific computational models of the heart are powerful tools for cardiovascular research and medicine, with demonstrated applications in treatment planning, device evaluation, and surgical decision-making. Yet constructing such…

Medical Physics · Physics 2026-04-21 Aaron L. Brown , Ju Liu , Daniel B. Ennis , Alison L. Marsden

Deep neural networks have demonstrated promising performance on image recognition tasks. However, they may heavily rely on confounding factors, using irrelevant artifacts or bias within the dataset as the cue to improve performance. When a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Siyuan Yan , Zhen Yu , Xuelin Zhang , Dwarikanath Mahapatra , Shekhar S. Chandra , Monika Janda , Peter Soyer , Zongyuan Ge

To develop a preliminary understanding towards Graph Foundation Models, we study the extent to which pretrained Graph Neural Networks can be applied across datasets, an effort requiring to be agnostic to dataset-specific features and their…