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This paper introduces a search algorithm for index structures based on a B+ tree, specifically optimized for execution on a field-programmable gate array (FPGA). Our implementation efficiently traverses and reuses tree nodes by processing a…

Hardware Architecture · Computer Science 2026-04-24 Max Tzschoppe , Martin Wilhelm , Sven Groppe , Thilo Pionteck

Partitioning graphs into blocks of roughly equal size such that few edges run between blocks is a frequently needed operation in processing graphs. Recently, size, variety, and structural complexity of these networks has grown dramatically.…

Data Structures and Algorithms · Computer Science 2018-10-16 Yaroslav Akhremtsev , Peter Sanders , Christian Schulz

The $k$d-tree is one of the most widely used data structures to manage multi-dimensional data. Due to the ever-growing data volume, it is imperative to consider parallelism in $k$d-trees. However, we observed challenges in existing parallel…

Data Structures and Algorithms · Computer Science 2025-01-08 Ziyang Men , Zheqi Shen , Yan Gu , Yihan Sun

When simulating metabolite productions with genome-scale constraint-based metabolic models, gene deletion strategies are necessary to achieve growth-coupled production, which means cell growth and target metabolite production occur…

Quantitative Methods · Quantitative Biology 2025-11-18 Ziwei Yang , Takeyuki Tamura

Data and pipeline parallelism are key strategies for scaling neural network training across distributed devices, but their high communication cost necessitates co-located computing clusters with fast interconnects, limiting their…

We present a work-efficient parallel level-synchronous Breadth First Search (BFS) algorithm for shared-memory architectures which achieves the theoretical lower bound on parallel running time. The optimality holds regardless of the shape of…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-09-20 Jesmin Jahan Tithi , Yonatan Fogel , Rezaul Chowdhury

We develop an algorithm that finds the consensus of many different clustering solutions of a graph. We formulate the problem as a median set partitioning problem and propose a greedy optimization technique. Unlike other approaches that find…

Information Retrieval · Computer Science 2024-08-22 Md Taufique Hussain , Mahantesh Halappanavar , Samrat Chatterjee , Filippo Radicchi , Santo Fortunato , Ariful Azad

One of the most computationally intensive tasks in computational biology is de novo genome assembly, the decoding of the sequence of an unknown genome from redundant and erroneous short sequences. A common assembly paradigm identifies…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-21 Giulia Guidi , Oguz Selvitopi , Marquita Ellis , Leonid Oliker , Katherine Yelick , Aydin Buluc

High Speed computing meets ever increasing real-time computational demands through the leveraging of flexibility and parallelism. The flexibility is achieved when computing platform designed with heterogeneous resources to support…

Operating Systems · Computer Science 2015-01-08 Mahendra Vucha , Arvind Rajawat

Parallel thinking has emerged as a promising paradigm for reasoning, yet it imposes significant computational burdens. Existing efficiency methods primarily rely on local, per-trajectory signals and lack principled mechanisms to exploit…

Computation and Language · Computer Science 2026-02-12 Tong Zheng , Chengsong Huang , Runpeng Dai , Yun He , Rui Liu , Xin Ni , Huiwen Bao , Kaishen Wang , Hongtu Zhu , Jiaxin Huang , Furong Huang , Heng Huang

We present a shared-memory parallelization of flow-based refinement, which is considered the most powerful iterative improvement technique for hypergraph partitioning at the moment. Flow-based refinement works on bipartitions, so current…

Data Structures and Algorithms · Computer Science 2022-01-06 Lars Gottesbüren , Tobias Heuer , Peter Sanders

Smoothing filter is the method of choice for image preprocessing and pattern recognition. We present a new concurrent method for smoothing 2D object in binary case. Proposed method provides a parallel computation while preserving the…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-04-01 Ramzi Mahmoudi , Mohamed Akil

Solving inverse problems and achieving statistical rigour in landscape evolution models requires running many model realizations. Parallel computation is necessary to achieve this in a reasonable time. However, no previous algorithm is…

Computational Engineering, Finance, and Science · Computer Science 2019-01-23 Richard Barnes

It is not known how a cell manages to find a specific DNA sequence sufficiently fast to repair a broken chromosome through homologous recombination. I propose that the solution is based on a parallelized search implemented by freely…

Other Quantitative Biology · Quantitative Biology 2016-08-25 Johan Elf

Large-scale observational health databases are increasingly popular for conducting comparative effectiveness and safety studies of medical products. However, increasing number of patients poses computational challenges when fitting survival…

Computation · Statistics 2023-10-26 Jianxiao Yang , Martijn J. Schuemie , Xiang Ji , Marc A. Suchard

The rapid growth of large language models (LLMs) and the continuous release of new GPU products have significantly increased the demand for distributed training across heterogeneous GPU environments. In this paper, we present a…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-25 Yuxiao Wang , Yuedong Xu , Qingyang Duan , Yuxuan Liu , Lei Jiao , Yinghao Yu , Jun Wu

Breadth-first search (BFS) is a fundamental graph algorithm that presents significant challenges for parallel implementation due to irregular memory access patterns, load imbalance and synchronization overhead. In this paper, we introduce a…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-04 Marati Bhaskar , Raghavendra Kanakagiri

Subgraph isomorphism is a fundamental problem in graph analysis that seeks to find all instances of a pattern graph within a larger data graph while preserving structural relationships. This NP-complete problem is central to domains such as…

Data Structures and Algorithms · Computer Science 2026-03-09 Yulun Wang , Esteban Ginez , Jamie Friel , Yuval Baum , Jin-Sung Kim , Alex Shih , Oded Green

Genetic Programming (GP) is a computationally intensive technique which is naturally parallel in nature. Consequently, many attempts have been made to improve its run-time from exploiting highly parallel hardware such as GPUs. However, a…

Neural and Evolutionary Computing · Computer Science 2018-09-21 Darren M. Chitty

Genome sequence alignment is the core of many biological applications. The advancement of sequencing technologies produces a tremendous amount of data, making sequence alignment a critical bottleneck in bioinformatics analysis. The existing…

Hardware Architecture · Computer Science 2023-01-26 Weihong Xu , Saransh Gupta , Niema Moshiri , Tajana Rosing