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While graph-based dynamic programming (DP) is a cornerstone of genomics and network analytics, its efficiency is hampered by fundamentally conflicting computational patterns. Matrix-centric DP drives regular, compute-bound network…

Hardware Architecture · Computer Science 2026-04-20 Yanru Chen , Runyang Tian , Zheyu Li , Mahbod Afarin , Weihong Xu , Tajana Rosing

Modern parallel computing devices, such as the graphics processing unit (GPU), have gained significant traction in scientific and statistical computing. They are particularly well-suited to data-parallel algorithms such as the particle…

Computation · Statistics 2015-06-12 Lawrence M. Murray , Anthony Lee , Pierre E. Jacob

This paper studies the nucleus decomposition problem, which has been shown to be useful in finding dense substructures in graphs. We present a novel parallel algorithm that is efficient both in theory and in practice. Our algorithm achieves…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-08-12 Jessica Shi , Laxman Dhulipala , Julian Shun

Polynomial systems occur in many areas of science and engineering. Unlike general nonlinear systems, the algebraic structure enables to compute all solutions of a polynomial system. We describe our massive parallel predictor-corrector…

Mathematical Software · Computer Science 2015-05-05 Jan Verschelde , Xiangcheng Yu

This article presents an automatic approach to quickly derive a good solution for hardware resource partition and task granularity for task-based parallel applications on heterogeneous many-core architectures. Our approach employs a…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-03-10 Peng Zhang , Jianbin Fang , Canqun Yang , Chun Huang , Tao Tang , Zheng Wang

This paper studies the hierarchical clustering problem, where the goal is to produce a dendrogram that represents clusters at varying scales of a data set. We propose the ParChain framework for designing parallel hierarchical agglomerative…

Data Structures and Algorithms · Computer Science 2022-02-15 Shangdi Yu , Yiqiu Wang , Yan Gu , Laxman Dhulipala , Julian Shun

Finding cohesive subgraphs in a large graph has many important applications, such as community detection and biological network analysis. Clique is often a too strict cohesive structure since communities or biological modules rarely form as…

Data Structures and Algorithms · Computer Science 2024-06-11 Qihao Cheng , Da Yan , Tianhao Wu , Lyuheng Yuan , Ji Cheng , Zhongyi Huang , Yang Zhou

Polyspectral estimation is a problem of great importance in the analysis of nonlinear time series that has applications in biomedical signal processing, communications, geophysics, image, radar, sonar and speech processing, etc. Higher…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-05-31 Abdullah-Al Mamun , Zigeng Wang , Xingyu Cai , Nalini Ravishanker , Sanguthevar Rajasekaran

Heterogeneous multi core processors can offer diverse computing capabilities. The efficiency of Market Basket Analysis Algorithm can be improved with heterogeneous multi core processors. Market basket analysis algorithm utilises apriori…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-09-24 Aashiha Priyadarshni. L

A significant advancement in bioinformatics is using genome graph techniques to improve variation discovery across organisms. Traditional approaches, such as bwa mem, rely on linear reference genomes for genomic analyses but may introduce…

Genomics · Quantitative Biology 2025-05-14 Fathima Nuzla Ismail , Abira Sengupta

The most efficient algorithms for finding maximum independent sets in both theory and practice use reduction rules to obtain a much smaller problem instance called a kernel. The kernel can then be solved quickly using exact or heuristic…

Data Structures and Algorithms · Computer Science 2019-09-11 Demian Hespe , Christian Schulz , Darren Strash

Proteomics is the large-scale analysis of the proteins. The common method for identifying proteins and characterising their amino acid sequences is to digest the proteins into peptides, analyse the peptides using mass spectrometry and…

Computational Engineering, Finance, and Science · Computer Science 2019-02-05 Samaneh Azari , Bing Xue , Mengjie Zhang , Lifeng Peng

The problem of finding dense components of a graph is a widely explored area in data analysis, with diverse applications in fields and branches of study including community mining, spam detection, computer security and bioinformatics. This…

Information Retrieval · Computer Science 2021-03-02 B. D. M. De Zoysa , Y. A. M. M. A. Ali , M. D. I. Maduranga , Indika Perera , Saliya Ekanayake , Anil Vullikanti

The computational problem of inferring the full haplotype of a cell starting from read sequencing data is known as haplotype assembly, and consists in assigning all heterozygous Single Nucleotide Polymorphisms (SNPs) to exactly one of the…

Butterflies are the smallest non-trivial subgraph in bipartite graphs, and therefore having efficient computations for analyzing them is crucial to improving the quality of certain applications on bipartite graphs. In this paper, we design…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-06-18 Jessica Shi , Julian Shun

Motivation: The gene content regulates the biology of an organism. It varies between species and between individuals of the same species. Although tools have been developed to identify gene content changes in bacterial genomes, none is…

Genomics · Quantitative Biology 2024-05-30 Heng Li , Maximillian Marin , Maha Reda Farhat

The life of the modern world essentially depends on the work of the large artificial homogeneous networks, such as wired and wireless communication systems, networks of roads and pipelines. The support of their effective continuous…

Optimization and Control · Mathematics 2017-01-25 Dmitry Yu. Ignatov , Alexander N. Filippov , Andrey D. Ignatov , Xuecang Zhang

In recent times, the emergence of Large Language Models (LLMs) has resulted in increasingly larger model size, posing challenges for inference on low-resource devices. Prior approaches have explored offloading to facilitate low-memory…

Performance · Computer Science 2024-03-05 Xuanlei Zhao , Bin Jia , Haotian Zhou , Ziming Liu , Shenggan Cheng , Yang You

We study the problem of computing a full Conjunctive Query in parallel using $p$ heterogeneous machines. Our computational model is similar to the MPC model, but each machine has its own cost function mapping from the number of bits it…

Databases · Computer Science 2025-03-12 Simon Frisk , Paraschos Koutris

Discovering causal relationships from observational data is a crucial problem and it has applications in many research areas. The PC algorithm is the state-of-the-art constraint based method for causal discovery. However, runtime of the PC…

Artificial Intelligence · Computer Science 2016-11-11 Thuc Duy Le , Tao Hoang , Jiuyong Li , Lin Liu , Huawen Liu