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Bayesian optimization (BO) is a powerful class of algorithms for optimizing expensive black-box functions, but designing effective BO algorithms remains a manual, expertise-driven task. Recent advancements in Large Language Models (LLMs)…

Machine Learning · Computer Science 2025-05-28 Wenhu Li , Niki van Stein , Thomas Bäck , Elena Raponi

Neuromorphic computing shows promise for advancing computing efficiency and capabilities of AI applications using brain-inspired principles. However, the neuromorphic research field currently lacks standardized benchmarks, making it…

Artificial Intelligence · Computer Science 2025-01-16 Jason Yik , Korneel Van den Berghe , Douwe den Blanken , Younes Bouhadjar , Maxime Fabre , Paul Hueber , Weijie Ke , Mina A Khoei , Denis Kleyko , Noah Pacik-Nelson , Alessandro Pierro , Philipp Stratmann , Pao-Sheng Vincent Sun , Guangzhi Tang , Shenqi Wang , Biyan Zhou , Soikat Hasan Ahmed , George Vathakkattil Joseph , Benedetto Leto , Aurora Micheli , Anurag Kumar Mishra , Gregor Lenz , Tao Sun , Zergham Ahmed , Mahmoud Akl , Brian Anderson , Andreas G. Andreou , Chiara Bartolozzi , Arindam Basu , Petrut Bogdan , Sander Bohte , Sonia Buckley , Gert Cauwenberghs , Elisabetta Chicca , Federico Corradi , Guido de Croon , Andreea Danielescu , Anurag Daram , Mike Davies , Yigit Demirag , Jason Eshraghian , Tobias Fischer , Jeremy Forest , Vittorio Fra , Steve Furber , P. Michael Furlong , William Gilpin , Aditya Gilra , Hector A. Gonzalez , Giacomo Indiveri , Siddharth Joshi , Vedant Karia , Lyes Khacef , James C. Knight , Laura Kriener , Rajkumar Kubendran , Dhireesha Kudithipudi , Shih-Chii Liu , Yao-Hong Liu , Haoyuan Ma , Rajit Manohar , Josep Maria Margarit-Taulé , Christian Mayr , Konstantinos Michmizos , Dylan R. Muir , Emre Neftci , Thomas Nowotny , Fabrizio Ottati , Ayca Ozcelikkale , Priyadarshini Panda , Jongkil Park , Melika Payvand , Christian Pehle , Mihai A. Petrovici , Christoph Posch , Alpha Renner , Yulia Sandamirskaya , Clemens JS Schaefer , André van Schaik , Johannes Schemmel , Samuel Schmidgall , Catherine Schuman , Jae-sun Seo , Sadique Sheik , Sumit Bam Shrestha , Manolis Sifalakis , Amos Sironi , Kenneth Stewart , Matthew Stewart , Terrence C. Stewart , Jonathan Timcheck , Nergis Tömen , Gianvito Urgese , Marian Verhelst , Craig M. Vineyard , Bernhard Vogginger , Amirreza Yousefzadeh , Fatima Tuz Zohora , Charlotte Frenkel , Vijay Janapa Reddi

Efficient design of genomic perturbation experiments is crucial for accelerating drug discovery and therapeutic target identification, yet exhaustive perturbation of the human genome remains infeasible due to the vast search space of…

Machine Learning · Statistics 2026-03-24 Yanke Li , Tianyu Cui , Tommaso Mansi , Mangal Prakash , Rui Liao

Bayesian optimization has been successfully applied to optimize black-box functions where the number of evaluations is severely limited. However, in many real-world applications, it is hard or impossible to know in advance which designs are…

Recently, the Deep Learning community has become interested in evolutionary optimization (EO) as a means to address hard optimization problems, e.g. meta-learning through long inner loop unrolls or optimizing non-differentiable operators.…

Neural and Evolutionary Computing · Computer Science 2023-11-07 Robert Tjarko Lange , Yujin Tang , Yingtao Tian

Recent advances in quantum computing and the increasing availability of quantum hardware have substantially enhanced the practical relevance of quantum approaches to discrete optimization. Among these, the Quadratic Unconstrained Binary…

Quantum Physics · Physics 2026-02-12 Felix P. Broesamle , Stefan Nickel

We introduce a method combining variational autoencoders (VAEs) and deep metric learning to perform Bayesian optimisation (BO) over high-dimensional and structured input spaces. By adapting ideas from deep metric learning, we use label…

Bayesian optimization (BO ) is an effective method for optimizing expensive-to-evaluate black-box functions. While high-dimensional problems can be particularly challenging, due to the multitude of parameter choices and the potentially high…

Machine Learning · Computer Science 2025-04-09 Erik Hellsten , Carl Hvarfner , Leonard Papenmeier , Luigi Nardi

One key challenge in optimization is the selection of a suitable set of benchmark problems. A common goal is to find functions which are representative of a class of real-world optimization problems in order to ensure findings on the…

Neural and Evolutionary Computing · Computer Science 2025-05-15 Diederick Vermetten , Catalin-Viorel Dinu , Marcus Gallagher

Bayesian optimization (BO) is an efficient method for optimizing expensive black-box functions. In real-world applications, BO often faces a major problem of missing values in inputs. The missing inputs can happen in two cases. First, the…

Machine Learning · Computer Science 2020-06-22 Phuc Luong , Dang Nguyen , Sunil Gupta , Santu Rana , Svetha Venkatesh

Bayesian optimization (BO) is an efficient framework for optimization of black-box objectives when function evaluations are costly and gradient information is not easily accessible. BO has been successfully applied to automate the task of…

Machine Learning · Computer Science 2024-07-09 Pallavi Mitra , Felix Biessmann

Bayesian Optimization (BO) is a powerful method for optimizing black-box functions by combining prior knowledge with ongoing function evaluations. BO constructs a probabilistic surrogate model of the objective function given the covariates,…

Machine Learning · Statistics 2025-08-26 Roi Naveiro , Becky Tang

Comparison-Based Optimization (CBO) is an optimization paradigm that assumes only very limited access to the objective function f(x). Despite the growing relevance of CBO to real-world applications, this field has received little attention…

Optimization and Control · Mathematics 2023-03-27 Isha Slavin , Daniel McKenzie

Data-efficient learning algorithms are essential in many practical applications for which data collection is expensive, e.g., for the optimal deployment of wireless systems in unknown propagation scenarios. Meta-learning can address this…

Machine Learning · Computer Science 2022-05-25 Ivana Nikoloska , Osvaldo Simeone

We consider black-box optimization in which only an extremely limited number of function evaluations, on the order of around 100, are affordable and the function evaluations must be performed in even fewer batches of a limited number of…

Machine Learning · Computer Science 2021-03-19 Carlos Ansotegui , Meinolf Sellmann , Tapan Shah , Kevin Tierney

Discovering optimal designs through sequential data collection is essential in many real-world applications. While Bayesian Optimization (BO) has achieved remarkable success in this setting, growing attention has recently turned to…

Machine Learning · Computer Science 2026-04-22 Chih-Yu Chang , Qiyuan Chen , Tianhan Gao , David Fenning , Chinedum Okwudire , Neil Dasgupta , Wei Lu , Raed Al Kontar

Black-box optimization methods play an important role in many fields of computational simulation. In particular, such methods are often used in the design and modelling of biological systems, including proteins and their complexes with…

Biomolecules · Quantitative Biology 2023-02-08 Dmitry Morozov , Artem Melnikov , Vishal Shete , Michael Perelshtein

An essential problem in automated machine learning (AutoML) is that of model selection. A unique challenge in the sequential setting is the fact that the optimal model itself may vary over time, depending on the distribution of features and…

Machine Learning · Computer Science 2020-02-17 Yao Zhang , Daniel Jarrett , Mihaela van der Schaar

Black-box optimization is often encountered for decision-making in complex systems management, where the knowledge of system is limited. Under these circumstances, it is essential to balance the utilization of new information with…

Computation · Statistics 2025-01-15 Teng Lian , Jian-Qiang Hu , Yuhang Wu , Zeyu Zheng

Considering that the physical design of printed circuit board (PCB) follows the principle of modularized design, this paper proposes an automatic placement algorithm for functional modules. We first model the placement problem as a…

Other Computer Science · Computer Science 2025-02-21 Hangyuan Li , Zhaoyang Yang , Haotian Pang , Ning Xu , Yu Chen