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Several cellular activities, such as directed cell migration, are coordinated by an intricate network of biochemical reactions which lead to a polarised state of the cell, in which cellular symmetry is broken, causing the cell to have a…

Cell Behavior · Quantitative Biology 2018-09-13 Davide Cusseddu , Leah Edelstein-Keshet , John A. Mackenzie , Stéphanie Portet , Anotida Madzvamuse

The finite element simulation of dynamic wetting phenomena, requiring the computation of flow in a domain confined by intersecting a liquid-fluid free surface and a liquid-solid interface, with the three-phase contact line moving across the…

Computational Physics · Physics 2012-02-20 J. E. Sprittles , Y. D. Shikhmurzaev

We introduce a new abstraction for the representation and solution of multi-domain problems using finite element methods. This is an advance over previous work in that it achieves a single higher-level abstraction that represents…

Mathematical Software · Computer Science 2025-12-09 Koki Sagiyama , Lawrence Mitchell , David A. Ham

We present a numerical investigation of residual-based a posteriori error estimation for finite element discretizations of convection--diffusion equations stabilized by algebraic flux correction and related algebraic stabilization…

Numerical Analysis · Mathematics 2026-02-17 Naveed Ahmed , Abhinav Jha

The phenomenological model for cell shape deformation and cell migration (Chen et.al. 2018; Vermolen and Gefen 2012) is extended with the incorporation of cell traction forces and the evolution of cell equilibrium shapes as a result of cell…

Cell Behavior · Quantitative Biology 2021-04-27 Qiyao Peng , Fred Vermolen , Daphne Weihs

A recently developed Eulerian finite element method is applied to solve advection-diffusion equations posed on hypersurfaces. When transport processes on a surface dominate over diffusion, finite element methods tend to be unstable unless…

Numerical Analysis · Mathematics 2013-03-26 Maxim A. Olshanskii , Arnold Reusken , Xianmin Xu

We present a finite element framework for the numerical prediction of cavitating turbulent flows interacting with flexible structures. The vapor-fluid phases are captured through a homogeneous mixture model, with a scalar transport equation…

Fluid Dynamics · Physics 2024-01-01 Nihar B. Darbhamulla , Rajeev K. Jaiman

We present a new framework for expressing finite element methods on multiple intersecting meshes: multimesh finite element methods. The framework enables the use of separate meshes to discretize parts of a computational domain that are…

Numerical Analysis · Mathematics 2018-08-28 August Johansson , Benjamin Kehlet , Mats G. Larson , Anders Logg

We present a finite element approach for diffusion problems with thermal fluctuations based on a fluctuating hydrodynamics model. The governing transport equations are stochastic partial differential equations with a fluctuating forcing…

Numerical Analysis · Mathematics 2024-03-21 P. Martínez-Lera , M. De Corato

We develop a mixed finite element domain decomposition method on non-matching grids for the Biot system of poroelasticity. A displacement-pressure vector mortar function is introduced on the interfaces and utilized as a Lagrange multiplier…

Numerical Analysis · Mathematics 2024-09-13 Manu Jayadharan , Ivan Yotov

Computationally solving the equations of elasticity is a key component in many materials science and mechanics simulations. Phenomena such as deformation-induced microstructure evolution, microfracture, and microvoid nucleation are examples…

Computational Engineering, Finance, and Science · Computer Science 2021-12-08 Brandon Runnels , Vinamra Agrawal , Weiqun Zhang , Ann Almgren

In this study, we present a finite element solver for a thermodynamically consistent electrolyte model that accurately captures multicomponent ionic transport by incorporating key physical phenomena such as steric effects, solvation, and…

Computational Engineering, Finance, and Science · Computer Science 2026-01-28 Jan Habscheid , Satyvir Singh , Lambert Theisen , Stefanie Braun , Manuel Torrilhon

We define a generalized finite element method for the discretization of elliptic partial differential equations in heterogeneous media. An adaptive local finite element basis (AL basis) on a coarse mesh which does not resolve the matrix of…

Numerical Analysis · Mathematics 2017-03-21 Monika Weymuth

Cell blebs are protrusions of the cell membrane and can be instrumental for cell migration. We derive a continuum model for the mechanical and geometrical aspects of the onset of blebbing in terms of a force balance. It is abstract and…

Numerical Analysis · Mathematics 2020-03-03 Björn Stinner , Andreas Dedner , Adam Nixon

We develop a unified theory for continuous in time finite element discretisations of partial differential equations posed in evolving domains including the consideration of equations posed on evolving surfaces and bulk domains as well…

Numerical Analysis · Mathematics 2020-07-21 Charles M. Elliott , Thomas Ranner

In this paper we propose a new method to stabilise non-symmetric indefinite problems. The idea is to solve a forward and an adjoint problem simultaneously using a suitable stabilised finite element method. Both stabilisation of the element…

Numerical Analysis · Mathematics 2013-08-05 Erik Burman

The purpose of this work is to investigate the behavior of Multiscale Finite Element type methods for advection-diffusion problems in the advection-dominated regime. We present, study and compare various options to address the issue of the…

Numerical Analysis · Mathematics 2015-11-30 Claude Le Bris , Frederic Legoll , François Madiot

The form and evolution of multi-phase biomembranes is of fundamental importance in order to understand living systems. In order to describe these membranes, we consider a mathematical model based on a Canham--Helfrich--Evans two-phase…

Numerical Analysis · Mathematics 2021-07-20 Harald Garcke , Robert Nürnberg

In the analysis of composite materials with heterogeneous microstructures, full resolution of the heterogeneities using classical numerical approaches can be computationally prohibitive. This paper presents a micromechanics-enhanced finite…

Materials Science · Physics 2011-11-08 J. Novák , Ł. Kaczmarczyk , P. Grassl , J. Zeman , C. J. Pearce

This work proposes a mixed finite element method for the Biot poroelasticity equations that employs the lowest-order Raviart-Thomas finite element space for the solid displacement and piecewise constants for the fluid pressure. The method…

Numerical Analysis · Mathematics 2022-12-26 Wietse M. Boon , Alessio Fumagalli , Anna Scotti