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Recent advances in natural language processing (NLP), particularly with the emergence of large language models (LLMs), have significantly enhanced the field of textual analysis. However, while these developments have yielded substantial…

Computation and Language · Computer Science 2026-01-15 Vishesh Prasad , Brian Kim , Nickvash Kani

Drug discovery remains a slow and expensive process that involves many steps, from detecting the target structure to obtaining approval from the Food and Drug Administration (FDA), and is often riddled with safety concerns. Accurate…

Quantitative Methods · Quantitative Biology 2025-08-22 Ali Vefghi , Zahed Rahmati , Mohammad Akbari

Knowledge is a formal way of understanding the world, providing a human-level cognition and intelligence for the next-generation artificial intelligence (AI). One of the representations of knowledge is semantic relations between entities.…

Computation and Language · Computer Science 2021-02-09 Hailin Wang , Ke Qin , Rufai Yusuf Zakari , Guoming Lu , Jin Yin

The scarcity of annotated datasets for clinical information extraction in non-English languages hinders the evaluation of large language model (LLM)-based methods developed primarily in English. In this study, we present the first…

Computation and Language · Computer Science 2026-01-15 Aidana Aidynkyzy , Oğuz Dikenelli , Oylum Alatlı , Şebnem Bora

The goal of dialogue relation extraction (DRE) is to identify the relation between two entities in a given dialogue. During conversations, speakers may expose their relations to certain entities by explicit or implicit clues, such evidences…

Computation and Language · Computer Science 2022-07-26 Po-Wei Lin , Shang-Yu Su , Yun-Nung Chen

Relation Extraction (RE), the task of detecting and characterizing semantic relations between entities in text, has gained much importance in the last two decades, mainly in the biomedical domain. Many papers have been published on Relation…

Artificial Intelligence · Computer Science 2020-01-14 Rinaldo Lima , Bernard Espinasse , Fred Freitas

Few-shot relation extraction aims to recognize novel relations with few labeled sentences in each relation. Previous metric-based few-shot relation extraction algorithms identify relationships by comparing the prototypes generated by the…

Computation and Language · Computer Science 2023-05-12 Zhongju Yuan , Zhenkun Wang , Genghui Li

The surging amount of biomedical literature & digital clinical records presents a growing need for text mining techniques that can not only identify but also semantically relate entities in unstructured data. In this paper we propose a text…

Computation and Language · Computer Science 2021-12-28 Hasham Ul Haq , Veysel Kocaman , David Talby

Document-level relation extraction is a complex human process that requires logical inference to extract relationships between named entities in text. Existing approaches use graph-based neural models with words as nodes and edges as…

Computation and Language · Computer Science 2019-09-04 Fenia Christopoulou , Makoto Miwa , Sophia Ananiadou

Drug side effects are a major global health concern, necessitating advanced methods for their accurate detection and analysis. While Large Language Models (LLMs) offer promising conversational interfaces, their inherent limitations,…

Information Retrieval · Computer Science 2025-07-21 Shad Nygren , Pinar Avci , Andre Daniels , Reza Rassol , Afshin Beheshti , Diego Galeano

The integration of Large Language Models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating drug discovery, and optimizing…

Quantitative Methods · Quantitative Biology 2024-09-10 Yizhen Zheng , Huan Yee Koh , Maddie Yang , Li Li , Lauren T. May , Geoffrey I. Webb , Shirui Pan , George Church

Document-Level Biomedical Relation Extraction (Bio-RE) aims to identify relations between biomedical entities within extensive texts, serving as a crucial subfield of biomedical text mining. Existing Bio-RE methods struggle with…

Computation and Language · Computer Science 2025-01-10 Yufei Shang , Yanrong Guo , Shijie Hao , Richang Hong

Systematic comparison of methods for relation extraction (RE) is difficult because many experiments in the field are not described precisely enough to be completely reproducible and many papers fail to report ablation studies that would…

Computation and Language · Computer Science 2021-07-14 Geeticka Chauhan , Matthew B. A. McDermott , Peter Szolovits

Simultaneous administration of multiple drugs can have synergistic or antagonistic effects as one drug can affect activities of other drugs. Synergistic effects lead to improved therapeutic outcomes, whereas, antagonistic effects can be…

Computation and Language · Computer Science 2017-08-15 Sunil Kumar Sahu , Ashish Anand

In our study, we evaluated large language model (LLM) performance on pharmacy licensure-style question-answering tasks and developed an external knowledge integration method to improve accuracy. We benchmarked ten LLMs with varying…

Document-level relation extraction aims to extract relations among entities within a document. Compared with its sentence-level counterpart, Document-level relation extraction requires inference over multiple sentences to extract complex…

Computation and Language · Computer Science 2022-08-05 Liang Zhang , Yidong Cheng

Many real world systems need to operate on heterogeneous information networks that consist of numerous interacting components of different types. Examples include systems that perform data analysis on biological information networks; social…

Artificial Intelligence · Computer Science 2017-07-26 Parisa Kordjamshidi , Sameer Singh , Daniel Khashabi , Christos Christodoulopoulos , Mark Summons , Saurabh Sinha , Dan Roth

Large language models (LLMs) have created a new paradigm for natural language processing. Despite their advancement, LLM-based methods still lag behind traditional approaches in document-level relation extraction (DocRE), a critical task…

Computation and Language · Computer Science 2024-12-10 Xingzuo Li , Kehai Chen , Yunfei Long , Min Zhang

Predicting and discovering drug-drug interactions (DDIs) using machine learning has been studied extensively. However, most of the approaches have focused on text data or textual representation of the drug structures. We present the first…

Machine Learning · Computer Science 2021-03-22 Devendra Singh Dhami , Siwen Yan , Gautam Kunapuli , David Page , Sriraam Natarajan

Relation extraction in the biomedical domain is challenging due to the lack of labeled data and high annotation costs, needing domain experts. Distant supervision is commonly used to tackle the scarcity of annotated data by automatically…

Computation and Language · Computer Science 2022-09-14 Saadullah Amin , Pasquale Minervini , David Chang , Pontus Stenetorp , Günter Neumann