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Cross-modality translation between MRI and PET imaging is challenging due to the distinct mechanisms underlying these modalities. Blood-based biomarkers (BBBMs) are revolutionizing Alzheimer's disease (AD) detection by identifying patients…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Yanxi Chen , Yi Su , Celine Dumitrascu , Kewei Chen , David Weidman , Richard J Caselli , Nicholas Ashton , Eric M Reiman , Yalin Wang

Computed tomography (CT) is a major medical imaging modality. Clinical CT scenarios, such as low-dose screening, sparse-view scanning, and metal implants, often lead to severe noise and artifacts in reconstructed images, requiring improved…

Image and Video Processing · Electrical Eng. & Systems 2025-06-04 Wenjun Xia , Chuang Niu , Ge Wang

Positron Emission Tomography (PET) is an imaging technique which can be used to investigate chemical changes in human biological processes such as cancer development or neurochemical reactions. Most dynamic PET scans are currently analyzed…

Applications · Statistics 2014-11-11 Ci-Ren Jiang , John A D Aston , Jane-Ling Wang

Recently, CycleGAN was shown to provide high-performance, ultra-fast denoising for low-dose X-ray computed tomography (CT) without the need for a paired training dataset. Although this was possible thanks to cycle consistency, CycleGAN…

Image and Video Processing · Electrical Eng. & Systems 2021-04-20 Taesung Kwon , Jong Chul Ye

Functional electrical stimulation (FES) has been increasingly integrated with other rehabilitation devices, including robots. FES cycling is one of the common FES applications in rehabilitation, which is performed by stimulating leg muscles…

Robotics · Computer Science 2023-11-17 Nat Wannawas , A. Aldo Faisal

Intra-cardiac Echocardiography (ICE) plays a critical role in Electrophysiology (EP) and Structural Heart Disease (SHD) interventions by providing real-time visualization of intracardiac structures. However, maintaining continuous…

Image and Video Processing · Electrical Eng. & Systems 2025-05-12 Jaeyoung Huh , Ankur Kapoor , Young-Ho Kim

Probabilistic estimation of cardiac electrophysiological model parameters serves an important step towards model personalization and uncertain quantification. The expensive computation associated with these model simulations, however, makes…

Understanding the progression trajectories of diseases is crucial for early diagnosis and effective treatment planning. This is especially vital for life-threatening conditions such as Idiopathic Pulmonary Fibrosis (IPF), a chronic,…

Image and Video Processing · Electrical Eng. & Systems 2025-02-11 An Zhao , Moucheng Xu , Ahmed H. Shahin , Wim Wuyts , Mark G. Jones , Joseph Jacob , Daniel C. Alexander

Dynamic prediction, which typically refers to the prediction of future outcomes using historical records, is often of interest in biomedical research. For datasets with large sample sizes, high measurement density, and complex correlation…

Methodology · Statistics 2024-12-04 Ying Jin , Andrew Leroux

Robots operating in human environments need various skills, like slow and fast walking, turning, side-stepping, and many more. However, building robot controllers that can exhibit such a large range of behaviors is a challenging problem…

Robotics · Computer Science 2022-02-28 Tianyu Li , Jungdam Won , Sehoon Ha , Akshara Rai

The expected decrease in system inertia and frequency stability motivates the development and maintenance of dynamic system models by Transmission System Operators. However, some dynamic model parameters can be unavailable due to market…

Signal Processing · Electrical Eng. & Systems 2025-05-27 Dawn Virginillo , Asja Derviškadić , Mario Paolone

Dynamic Positron Emission Tomography (dPET) imaging and Time-Activity Curve (TAC) analyses are essential for understanding and quantifying the biodistribution of radiopharmaceuticals over time and space. Traditional compartmental modeling,…

Machine Learning · Computer Science 2024-06-03 Niloufar Zakariaei , Arman Rahmim , Eldad Haber

Variational Autoencoders (VAEs) are powerful generative models widely used for learning interpretable latent spaces, quantifying uncertainty, and compressing data for downstream generative tasks. VAEs typically rely on diagonal Gaussian…

Machine Learning · Computer Science 2025-06-03 Peter Sorrenson , Lukas Lührs , Hans Olischläger , Ullrich Köthe

Diffusion MRI is a neuroimaging technique measuring the anatomical structure of tissues. Using diffusion MRI to construct the connections of tissues, known as fiber tracking, is one of the most important uses of diffusion MRI. Many…

Methodology · Statistics 2019-06-18 Zhou Lan , Brian J Reich

Inference for mechanistic models is challenging because of nonlinear interactions between model parameters and a lack of identifiability. Here we focus on a specific class of mechanistic models, which we term stable differential equations.…

Computation · Statistics 2017-12-13 Philip Maybank , Ingo Bojak , Richard G. Everitt

Ultrafast intracardiac echocardiography (ICE) uses unfocused transmissions to capture cardiac motion at frame rates exceeding 1 kHz. While this enables real-time visualization of rapid dynamics, image quality is often degraded by…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Rémi Delaunay , Christoph Hennersperger , Stefan Wörz

We propose in this paper Periodic Interaction Primitives - a probabilistic framework that can be used to learn compact models of periodic behavior. Our approach extends existing formulations of Interaction Primitives to periodic movement…

Whole-body Positron Emission Tomography (PET) registration is essential for multi-parametric tumor characterization and assessment of metastatic disease progression. In deep learning-based deformable registration, the dense displacement…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Xiangcen Wu , Ruohua Chen , Sichun Li , Qianye Yang , Sheng Liu , Jianjun Liu , Zhaoheng Xie

Automated animal behavior analysis relies on long-term, interpretable individual trajectories; however, multi-animal tracking in space science experimental videos remains highly challenging due to weak appearance cues, low-quality imaging,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-30 Jianing You , Han Wang , Kang Liu , Jiale Ding , Fengjie Chu , Zihan Guo , Shengyang Li

Active stress models in cardiac biomechanics account for the mechanical deformation caused by muscle activity, thus providing a link between the electrophysiological and mechanical properties of the tissue. The accurate assessment of active…

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