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This paper presents Fd-CycleGAN, an image-to-image (I2I) translation framework that enhances latent representation learning to approximate real data distributions. Building upon the foundation of CycleGAN, our approach integrates Local…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Shivangi Nigam , Adarsh Prasad Behera , Shekhar Verma , P. Nagabhushan

Clinical decision support using deep neural networks has become a topic of steadily growing interest. While recent work has repeatedly demonstrated that deep learning offers major advantages for medical image classification over traditional…

Image and Video Processing · Electrical Eng. & Systems 2022-06-10 Alexander Katzmann , Oliver Taubmann , Stephen Ahmad , Alexander Mühlberg , Michael Sühling , Horst-Michael Groß

Elucidating the biomechanical behavior of the myocardium is crucial for understanding cardiac physiology, but cannot be directly inferred from clinical imaging and typically requires finite element (FE) simulations. However, conventional FE…

Medical Physics · Physics 2025-06-27 Siyu Mu , Wei Xuan Chan , Choon Hwai Yap

Positron emission tomography (PET) serves as an essential tool for diagnosis of encephalopathy and brain science research. However, it suffers from the limited choice of tracers. Nowadays, with the wide application of PET imaging in…

Imaging in clinical oncology trials provides a wealth of information that contributes to the drug development process, especially in early phase studies. This paper focuses on kinetic modeling in DCE-MRI, inspired by mixed-effects models…

Applications · Statistics 2020-04-22 Volker J. Schmid , Brandon Whitcher , Anwar R. Padhani , N. Jane Taylor , Guang-Zhong Yang

In the context of dynamic emission tomography, the conventional processing pipeline consists of independent image reconstruction of single time frames, followed by the application of a suitable kinetic model to time activity curves (TACs)…

Applications · Statistics 2018-08-28 Michele Scipioni , Stefano Pedemonte , Maria Filomena Santarelli , Luigi Landini

Purpose: To apply tracer kinetic models as temporal constraints during reconstruction of under-sampled dynamic contrast enhanced (DCE) MRI. Methods: A library of concentration v.s time profiles is simulated for a range of physiological…

Patient-specific cardiac computational models are essential for the efficient realization of precision medicine and in-silico clinical trials using digital twins. Cardiac digital twins can provide non-invasive characterizations of cardiac…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Lei Li , Julia Camps , Abhirup Banerjee , Marcel Beetz , Blanca Rodriguez , Vicente Grau

VIS-NIR face recognition remains a challenging task due to the distinction between spectral components of two modalities and insufficient paired training data. Inspired by the CycleGAN, this paper presents a method aiming to translate VIS…

Computer Vision and Pattern Recognition · Computer Science 2019-04-26 Huijiao Wang , Li Wang , Xulei Yang , Lei Yu , Haijian Zhang

Recently, the cycle-consistent generative adversarial networks (CycleGAN) has been widely used for synthesis of multi-domain medical images. The domain-specific nonlinear deformations captured by CycleGAN make the synthesized images…

Computer Vision and Pattern Recognition · Computer Science 2018-08-14 Chengjia Wang , Gillian Macnaught , Giorgos Papanastasiou , Tom MacGillivray , David Newby

Anatomical structures such as blood vessels in contrast-enhanced CT (ceCT) images can be challenging to segment due to the variability in contrast medium diffusion. The combined use of ceCT and contrast-free (CT) CT images can improve the…

Image and Video Processing · Electrical Eng. & Systems 2022-10-05 Giammarco La Barbera , Haithem Boussaid , Francesco Maso , Sabine Sarnacki , Laurence Rouet , Pietro Gori , Isabelle Bloch

Background: In medical imaging, images are usually treated as deterministic, while their uncertainties are largely underexplored. Purpose: This work aims at using deep learning to efficiently estimate posterior distributions of imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-03-20 Xiaofeng Liu , Thibault Marin , Tiss Amal , Jonghye Woo , Georges El Fakhri , Jinsong Ouyang

Extensive studies suggested that fluid mechanical markers of intracranial aneurysms (IAs) derived from Computational Fluid Dynamics (CFD) can indicate disease progression risks, but to date this has not been translated clinically. This is…

Machine Learning · Computer Science 2026-01-30 Yiying Sheng , Wenhao Ding , Dylan Roi , Leonard Leong Litt Yeo , Hwa Liang Leo , Choon Hwai Yap

Positron Emission Tomography (PET) is an important tool for studying Alzheimer's disease (AD). PET scans can be used as diagnostics tools, and to provide molecular characterization of patients with cognitive disorders. However, multiple…

Image and Video Processing · Electrical Eng. & Systems 2021-07-13 Bo Zhou , Rui Wang , Ming-Kai Chen , Adam P. Mecca , Ryan S. O'Dell , Christopher H. Van Dyck , Richard E. Carson , James S. Duncan , Chi Liu

Polarimetric imaging, along with deep learning, has shown improved performances on different tasks including scene analysis. However, its robustness may be questioned because of the small size of the training datasets. Though the issue…

Computer Vision and Pattern Recognition · Computer Science 2022-06-16 Cyprien Ruffino , Rachel Blin , Samia Ainouz , Gilles Gasso , Romain Hérault , Fabrice Meriaudeau , Stéphane Canu

The aim of this paper is to discuss potential advances in PET kinetic models and direct reconstruction of kinetic parameters. As a prominent example we focus on a typical task in perfusion imaging and derive a system of…

Optimization and Control · Mathematics 2014-11-20 Louise Reips , Martin Burger , Ralf Engbers

In oncology, Positron Emission Tomography-Computed Tomography (PET/CT) is widely used in cancer diagnosis, staging, and treatment monitoring, as it combines anatomical details from CT with functional metabolic activity and molecular marker…

Unpaired image-to-image translation has broad applications in art, design, and scientific simulations. One early breakthrough was CycleGAN that emphasizes one-to-one mappings between two unpaired image domains via generative-adversarial…

Computer Vision and Pattern Recognition · Computer Science 2022-10-19 Dmitrii Torbunov , Yi Huang , Haiwang Yu , Jin Huang , Shinjae Yoo , Meifeng Lin , Brett Viren , Yihui Ren

Patlak model is widely used in 18F-FDG dynamic positron emission tomography (PET) imaging, where the estimated parametric images reveal important biochemical and physiology information. Because of better noise modeling and more information…

Medical Physics · Physics 2020-09-15 Nuobei Xie , Kuang Gong , Ning Guo , Zhixing Qin , Jianan Cui , Zhifang Wu , Huafeng Liu , Quanzheng Li

Approximating wind flows using computational fluid dynamics (CFD) methods can be time-consuming. Creating a tool for interactively designing prototypes while observing the wind flow change requires simpler models to simulate faster. Instead…

Computer Vision and Pattern Recognition · Computer Science 2022-01-05 Henrik Hoeiness , Kristoffer Gjerde , Luca Oggiano , Knut Erik Teigen Giljarhus , Massimiliano Ruocco