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This paper is motivated by the recent interest in the analysis of high dimen- sional microbiome data. A key feature of this data is the presence of `structural zeros' which are microbes missing from an observation vector due to an…

Applications · Statistics 2016-05-23 Abhishek Kaul , Ori Davidov , Shyamal D. Peddada

Compositional data are met in many different fields, such as economics, archaeometry, ecology, geology and political sciences. Regression where the dependent variable is a composition is usually carried out via a log-ratio transformation of…

Methodology · Statistics 2017-06-08 Michail Tsagris , Connie Stewart

We investigate one/two-sample mean tests for high-dimensional compositional data when the number of variables is comparable with the sample size, as commonly encountered in microbiome research. Existing methods mainly focus on max-type test…

Statistics Theory · Mathematics 2024-04-15 Qianqian Jiang , Wenbo Li , Zeng Li

In this work, we present a novel downscaling procedure for compositional quantities based on the Aitchison geometry. The method is able to naturally consider compositional constraints, i.e. unit-sum and positivity. We show that the method…

We introduce a novel approach to compositional data analysis based on $L^{\infty}$-normalization, addressing challenges posed by zero-rich high-throughput data. Traditional methods like Aitchison's transformations require excluding zeros,…

Computation · Statistics 2025-03-28 Pawel Gajer , Jacques Ravel

In compositional data, an observation is a vector with non-negative components which sum to a constant, typically 1. Data of this type arise in many areas, such as geology, archaeology, biology, economics and political science amongst…

Methodology · Statistics 2015-11-25 Michail Tsagris

We present a new model for analyzing compositional data with structural zeros. Inspired by \cite{butler2008} who suggested a model in the presence of zero values in the data we propose a model that treats the zero values in a different…

Methodology · Statistics 2022-08-30 Michail Tsagris

The growing use of high-throughput sequencing (HTS) has enabled the large-scale production of compositional count data, driving progress in microbiome research. However, such count data are often high-dimensional, over-dispersed, and…

Other Statistics · Statistics 2026-05-22 Wenqi Tang , Kamila Fačevicová , Klaus Nordhausen , Sara Taskinen

In compositional data analysis an observation is a vector containing non-negative values, only the relative sizes of which are considered to be of interest. Without loss of generality, a compositional vector can be taken to be a vector of…

Methodology · Statistics 2015-06-18 Michail Tsagris , Simon Preston , Andrew T. A. Wood

We propose a novel method to detect and date structural breaks in the entire distribution of functional data. Theoretical guarantees are developed for our procedure under fewer assumptions than in the existing work. In particular, we…

Methodology · Statistics 2025-04-17 Peijun Sang , Bing Li

Identifying which taxa in our microbiota are associated with traits of interest is important for advancing science and health. However, the identification is challenging because the measured vector of taxa counts (by amplicon sequencing) is…

Genomics · Quantitative Biology 2020-03-31 Barak Brill , Amnon Amir , Ruth Heller

This paper introduces a rectified and renormalized Fisher-Bingham model for compositional data with zeros, motivated in part by the presence of zeros in microbiota studies. The approach represents compositions through a square-root…

Methodology · Statistics 2026-04-29 Eugene Han , Marahi Perez-Tamayo , Hannah D. Holscher , Ruoqing Zhu

Traditional methods for the analysis of compositional data consider the log-ratios between all different pairs of variables with equal weight, typically in the form of aggregated contributions. This is not meaningful in contexts where it is…

Methodology · Statistics 2022-01-27 Christopher Rieser , Peter Filzmoser

The development of John Aitchison's approach to compositional data analysis is followed since his paper read to the Royal Statistical Society in 1982. Aitchison's logratio approach, which was proposed to solve the problematic aspects of…

Methodology · Statistics 2023-01-19 Michael Greenacre , Eric Grunsky , John Bacon-Shone , Ionas Erb , Thomas Quinn

Compositional data and multivariate count data with known totals are challenging to analyse due to the non-negativity and sum-to-one constraints on the sample space. It is often the case that many of the compositional components are highly…

Methodology · Statistics 2020-12-24 Janice L. Scealy , Andrew T. A. Wood

In compositional data, an observation is a vector with non-negative components which sum to a constant, typically 1. Data of this type arise in many areas, such as geology, archaeology, biology, economics and political science among others.…

Methodology · Statistics 2015-06-18 Michail Tsagris

We investigate properties of a bootstrap-based methodology for testing hypotheses about equality of certain characteristics of the distributions between different populations in the context of functional data. The suggested testing…

Statistics Theory · Mathematics 2016-09-29 Efstathios Paparoditis , Theofanis Sapatinas

We consider functional data which have only been observed on a subset of their domain. This paper aims to develop statistical tests to determine whether the function and the domain over which it is observed are independent. The assumption…

Methodology · Statistics 2025-12-04 Maximilian Ofner , Siegfried Hörmann , David Kraus , Dominik Liebl

Compositional data, also referred to as simplicial data, naturally arise in many scientific domains such as geochemistry, microbiology, and economics. In such domains, obtaining sensible lower-dimensional representations and modes of…

There are two notoriously hard problems in cluster analysis, estimating the number of clusters, and checking whether the population to be clustered is not actually homogeneous. Given a dataset, a clustering method and a cluster validation…

Methodology · Statistics 2015-02-10 Christian Hennig , Chien-Ju Lin
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