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Magnetic resonance imaging (MRI) plays an important role in modern medical diagnostic but suffers from prolonged scan time. Current deep learning methods for undersampled MRI reconstruction exhibit good performance in image de-aliasing…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Min Xiao , Zi Wang , Jiefeng Guo , Xiaobo Qu

Single-cell RNA sequencing (scRNA-seq) enables researchers to analyze gene expression at single-cell level. One important task in scRNA-seq data analysis is unsupervised clustering, which helps identify distinct cell types, laying down the…

Genomics · Quantitative Biology 2023-12-29 Weikang Jiang , Jinxian Wang , Jihong Guan , Shuigeng Zhou

Point cloud denoising aims to restore clean point clouds from raw observations corrupted by noise and outliers while preserving the fine-grained details. We present a novel deep learning-based denoising model, that incorporates normalizing…

Computer Vision and Pattern Recognition · Computer Science 2022-07-26 Aihua Mao , Zihui Du , Yu-Hui Wen , Jun Xuan , Yong-Jin Liu

Training deep neural network (DNN) with noisy labels is practically challenging since inaccurate labels severely degrade the generalization ability of DNN. Previous efforts tend to handle part or full data in a unified denoising flow via…

Computer Vision and Pattern Recognition · Computer Science 2022-08-24 Boshen Zhang , Yuxi Li , Yuanpeng Tu , Jinlong Peng , Yabiao Wang , Cunlin Wu , Yang Xiao , Cairong Zhao

We introduce a new class of generative diffusion models that, unlike conventional denoising diffusion models, achieve a time-homogeneous structure for both the noising and denoising processes, allowing the number of steps to adaptively…

Machine Learning · Statistics 2026-01-23 Sören Christensen , Jan Kallsen , Claudia Strauch , Lukas Trottner

Early detection through imaging and accurate diagnosis is crucial in mitigating the high mortality rate associated with breast cancer. However, locating tumors from low-resolution and high-noise medical images is extremely challenging.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Feiyan Feng , Tianyu Liu , Hong Wang , Jun Zhao , Wei Li , Yanshen Sun

With ongoing developments and innovations in single-cell RNA sequencing methods, advancements in sequencing performance could empower significant discoveries as well as new emerging possibilities to address biological and medical…

Applications · Statistics 2019-12-19 Jiawei Long , Yu Xia

We consider here a classification method that balances two objectives: large similarity within the samples in the cluster, and large dissimilarity between the cluster and its complement. The method, referred to as HNC or SNC, requires seed…

Machine Learning · Computer Science 2025-03-05 Dorit Hochbaum , Torpong Nitayanont

Network models provide a powerful framework for analysing single-cell count data, facilitating the characterisation of cellular identities, disease mechanisms, and developmental trajectories. However, uncertainty modeling in unsupervised…

Genomics · Quantitative Biology 2026-04-27 Shanshan Ren , Thomas E. Bartlett , Lina Gerontogianni , Swati Chandna

Diffusion models struggle to produce samples that respect constraints, a common requirement in scientific applications. Recent approaches have introduced regularization terms in the loss or guidance methods during sampling to enforce such…

Machine Learning · Computer Science 2026-02-06 Victor M. Yeom-Song , Severi Rissanen , Arno Solin , Samuel Kaski , Mingfei Sun

In recent years, the field of single-cell data analysis has seen a marked advancement in the development of clustering methods. Despite advancements, most of these algorithms still concentrate on analyzing the provided single-cell matrix…

Machine Learning · Computer Science 2023-12-18 Dayu Hu , Ke Liang , Hao Yu , Xinwang Liu

Accurate interpolation of seismic data is crucial for improving the quality of imaging and interpretation. In recent years, deep learning models such as U-Net and generative adversarial networks have been widely applied to seismic data…

Diffusion models have recently achieved great success in the synthesis of high-quality images and videos. However, the existing denoising techniques in diffusion models are commonly based on step-by-step noise predictions, which suffers…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Hancheng Ye , Jiakang Yuan , Renqiu Xia , Xiangchao Yan , Tao Chen , Junchi Yan , Botian Shi , Bo Zhang

We present a deep neural network to reduce coherent noise in three-dimensional quantitative phase imaging. Inspired by the cycle generative adversarial network, the denoising network was trained to learn a transform between two image…

Co-clustering exploits the duality of instances and features to simultaneously uncover meaningful groups in both dimensions, often outperforming traditional clustering in high-dimensional or sparse data settings. Although recent deep…

Machine Learning · Computer Science 2025-04-10 Ashwin Vinod , Chandrajit Bajaj

With the success of image generation, generative diffusion models are increasingly adopted for discriminative tasks, as pixel generation provides a unified perception interface. However, directly repurposing the generative denoising process…

Computer Vision and Pattern Recognition · Computer Science 2025-04-16 Ziqi Pang , Xin Xu , Yu-Xiong Wang

Diffusion models learn to denoise data and the trained denoiser is then used to generate new samples from the data distribution. In this paper, we revisit the diffusion sampling process and identify a fundamental cause of sample quality…

Machine Learning · Computer Science 2024-11-05 Yunshu Wu , Yingtao Luo , Xianghao Kong , Evangelos E. Papalexakis , Greg Ver Steeg

Deep clustering methods improve the performance of clustering tasks by jointly optimizing deep representation learning and clustering. While numerous deep clustering algorithms have been proposed, most of them rely on artificially…

Machine Learning · Computer Science 2024-01-30 Zhanwen Cheng , Feijiang Li , Jieting Wang , Yuhua Qian

In this paper, we propose an audio declipping method that takes advantages of both sparse optimization and deep learning. Since sparsity-based audio declipping methods have been developed upon constrained optimization, they are adjustable…

Audio and Speech Processing · Electrical Eng. & Systems 2022-02-17 Tomoro Tanaka , Kohei Yatabe , Masahiro Yasuda , Yasuhiro Oikawa

The swift advancement of single-cell RNA sequencing (scRNA-seq) technologies enables the investigation of cellular-level tissue heterogeneity. Cell annotation significantly contributes to the extensive downstream analysis of scRNA-seq data.…

Machine Learning · Computer Science 2024-11-28 Huifa Li , Jie Fu , Xinpeng Ling , Zhiyu Sun , Kuncan Wang , Zhili Chen