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We explore the hyperparameters and introduce a methodological framework to convert disease patterns from time series data of blood test results into correlation graphs for causal hypothesis exploration. The networks represent hypotheses…

Other Quantitative Biology · Quantitative Biology 2025-12-29 David Patrick Duys Montealegre , Alexander Fulton , Mahta Haghighat Ghahfarokhi , Abicumaran Uthamacumaran , Hector Zenil

The task of inferring high-level causal variables from low-level observations, commonly referred to as causal representation learning, is fundamentally underconstrained. As such, recent works to address this problem focus on various…

Machine Learning · Statistics 2024-03-26 Simon Bing , Urmi Ninad , Jonas Wahl , Jakob Runge

Discovering the causality from observational data is a crucial task in various scientific domains. With increasing awareness of privacy, data are not allowed to be exposed, and it is very hard to learn causal graphs from dispersed data,…

Machine Learning · Computer Science 2023-12-12 Dezhi Yang , Xintong He , Jun Wang , Guoxian Yu , Carlotta Domeniconi , Jinglin Zhang

We present a sound and complete algorithm, called iterative causal discovery (ICD), for recovering causal graphs in the presence of latent confounders and selection bias. ICD relies on the causal Markov and faithfulness assumptions and…

Machine Learning · Computer Science 2022-01-19 Raanan Y. Rohekar , Shami Nisimov , Yaniv Gurwicz , Gal Novik

Learning a causal directed acyclic graph from data is a challenging task that involves solving a combinatorial problem for which the solution is not always identifiable. A new line of work reformulates this problem as a continuous…

Machine Learning · Computer Science 2020-11-05 Philippe Brouillard , Sébastien Lachapelle , Alexandre Lacoste , Simon Lacoste-Julien , Alexandre Drouin

Sequential experimental design to discover interventions that achieve a desired outcome is a key problem in various domains including science, engineering and public policy. When the space of possible interventions is large, making an…

Machine Learning · Computer Science 2023-08-17 Jiaqi Zhang , Louis Cammarata , Chandler Squires , Themistoklis P. Sapsis , Caroline Uhler

Constraint-based methods and noise-based methods are two distinct families of methods proposed for uncovering causal graphs from observational data. However, both operate under strong assumptions that may be challenging to validate or could…

Artificial Intelligence · Computer Science 2024-05-01 Daria Bystrova , Charles K. Assaad , Julyan Arbel , Emilie Devijver , Eric Gaussier , Wilfried Thuiller

Causality is a central topic in scientific inquiry, yet for complex systems, the identification and analysis of synergistic causation remain a challenging and fundamental problem. In the context of causal relations among multivariate…

Machine Learning · Statistics 2026-05-06 Mingzhe Yang , Shuo Wang , Jiang Zhang

The gold standard for discovering causal relations is by means of experimentation. Over the last decades, alternative methods have been proposed that can infer causal relations between variables from certain statistical patterns in purely…

Machine Learning · Computer Science 2020-08-21 Joris M. Mooij , Sara Magliacane , Tom Claassen

We consider testing and learning problems on causal Bayesian networks as defined by Pearl (Pearl, 2009). Given a causal Bayesian network $\mathcal{M}$ on a graph with $n$ discrete variables and bounded in-degree and bounded `confounded…

Data Structures and Algorithms · Computer Science 2018-05-25 Jayadev Acharya , Arnab Bhattacharyya , Constantinos Daskalakis , Saravanan Kandasamy

Performing inference on data obtained through observational studies is becoming extremely relevant due to the widespread availability of data in fields such as healthcare, education, retail, etc. Furthermore, this data is accrued from…

Machine Learning · Computer Science 2021-02-18 Ankit Sharma , Garima Gupta , Ranjitha Prasad , Arnab Chatterjee , Lovekesh Vig , Gautam Shroff

Nonlinear causal discovery from observational data imposes strict identifiability assumptions on the formulation of structural equations utilized in the data generating process. The evaluation of structure learning methods under assumption…

Machine Learning · Statistics 2024-12-17 Georg Velev , Stefan Lessmann

Learning causality from observational data has received increasing interest across various scientific fields. However, most existing methods assume the absence of latent confounders and restrict the underlying causal graph to be acyclic,…

Methodology · Statistics 2025-11-18 Wei Jin , Lang Lang , Amanda B. Spence , Leah H. Rubin , Yanxun Xu

Learning causal relationships between variables from data is a fundamental research area with many applications across disciplines. Most existing causal discovery algorithms rely on the assumptions that (i) the underlying system is acyclic,…

Machine Learning · Computer Science 2026-05-19 Alpar Turkoglu , Muralikrishnna G. Sethuraman , Faramarz Fekri

We consider the problem of learning causal networks with interventions, when each intervention is limited in size under Pearl's Structural Equation Model with independent errors (SEM-IE). The objective is to minimize the number of…

Artificial Intelligence · Computer Science 2015-11-03 Karthikeyan Shanmugam , Murat Kocaoglu , Alexandros G. Dimakis , Sriram Vishwanath

We are not only observers but also actors of reality. Our capability to intervene and alter the course of some events in the space and time surrounding us is an essential component of how we build our model of the world. In this doctoral…

Artificial Intelligence · Computer Science 2023-09-19 Gilles Blondel

Learning causal structure from sampled data is a fundamental problem with applications in various fields, including healthcare, machine learning and artificial intelligence. Traditional methods predominantly rely on observational data, but…

Machine Learning · Computer Science 2024-08-12 Qiu Chengbo , Yang Kai

Causal discovery for dynamical systems poses a major challenge in fields where active interventions are infeasible. Most methods used to investigate these systems and their associated benchmarks are tailored to deterministic,…

Machine Learning · Computer Science 2025-10-13 Benjamin Herdeanu , Juan Nathaniel , Carla Roesch , Jatan Buch , Gregor Ramien , Johannes Haux , Pierre Gentine

Real-world problems, for example in climate applications, often require causal reasoning on spatially gridded time series data or data with comparable structure. While the underlying system is often believed to behave similarly at different…

Machine Learning · Computer Science 2026-02-16 Martin Rabel , Jakob Runge

We propose a novel machine learning approach for inferring causal variables of a target variable from observations. Our focus is on directly inferring a set of causal factors without requiring full causal graph reconstruction, which is…

Machine Learning · Computer Science 2025-10-01 Jang-Hyun Kim , Claudia Skok Gibbs , Sangdoo Yun , Hyun Oh Song , Kyunghyun Cho