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In artificial neural networks trained with gradient descent, the weights used for processing stimuli are also used during backward passes to calculate gradients. For the real brain to approximate gradients, gradient information would have…

Neurons and Cognition · Quantitative Biology 2020-02-04 Jordan Guerguiev , Konrad P. Kording , Blake A. Richards

The brain can learn to execute a wide variety of tasks quickly and efficiently. Nevertheless, most of the mechanisms that enable us to learn are unclear or incredibly complicated. Recently, considerable efforts have been made in…

Neural and Evolutionary Computing · Computer Science 2023-03-28 Mohammad Modiri

Predictive coding (PC) is a general theory of cortical function. The local, gradient-based learning rules found in one kind of PC model have recently been shown to closely approximate backpropagation. This finding suggests that this…

Neural and Evolutionary Computing · Computer Science 2021-12-09 Nick Alonso , Emre Neftci

In both machine learning and in computational neuroscience, plasticity in functional neural networks is frequently expressed as gradient descent on a cost. Often, this imposes symmetry constraints that are difficult to reconcile with local…

Neurons and Cognition · Quantitative Biology 2026-04-09 Timo Gierlich , Andreas Baumbach , Akos F. Kungl , Kevin Max , Mihai A. Petrovici

The brain is a nonlinear and highly Recurrent Neural Network (RNN). This RNN is surprisingly plastic and supports our astonishing ability to learn and execute complex tasks. However, learning is incredibly complicated due to the brain's…

Neural and Evolutionary Computing · Computer Science 2023-03-14 Mohammad Modiri

Plasticity circuits in the brain are known to be influenced by the distribution of the synaptic weights through the mechanisms of synaptic integration and local regulation of synaptic strength. However, the complex interplay of…

Neural and Evolutionary Computing · Computer Science 2021-04-26 Giorgia Dellaferrera , Stanislaw Wozniak , Giacomo Indiveri , Angeliki Pantazi , Evangelos Eleftheriou

Gradient-based first-order adaptive optimization methods such as the Adam optimizer are prevalent in training artificial networks, achieving the state-of-the-art results. This work attempts to answer the question whether it is viable for…

Neural and Evolutionary Computing · Computer Science 2022-12-20 Yukun Yang , Peng Li

Many of the recent advances in the field of artificial intelligence have been fueled by the highly successful backpropagation of error (BP) algorithm, which efficiently solves the credit assignment problem in artificial neural networks.…

Machine Learning · Computer Science 2023-01-25 Sander Dalm , Nasir Ahmad , Luca Ambrogioni , Marcel van Gerven

The brain processes information through many layers of neurons. This deep architecture is representationally powerful, but it complicates learning by making it hard to identify the responsible neurons when a mistake is made. In machine…

Neurons and Cognition · Quantitative Biology 2014-11-04 Timothy P. Lillicrap , Daniel Cownden , Douglas B. Tweed , Colin J. Akerman

Backpropagation is driving today's artificial neural networks (ANNs). However, despite extensive research, it remains unclear if the brain implements this algorithm. Among neuroscientists, reinforcement learning (RL) algorithms are often…

Neurons and Cognition · Quantitative Biology 2020-04-24 Benjamin James Lansdell , Prashanth Ravi Prakash , Konrad Paul Kording

Error backpropagation is an extremely effective algorithm for assigning credit in artificial neural networks. However, weight updates under Backprop depend on lengthy recursive computations and require separate output and error messages --…

Machine Learning · Computer Science 2014-11-25 David Balduzzi , Hastagiri Vanchinathan , Joachim Buhmann

Supervised learning in artificial neural networks typically relies on backpropagation, where the weights are updated based on the error-function gradients and sequentially propagated from the output layer to the input layer. Although this…

Neural and Evolutionary Computing · Computer Science 2023-06-06 Giorgia Dellaferrera , Gabriel Kreiman

A computational problem in biological reward-based learning is how credit assignment is performed in the nucleus accumbens (NAc). Much research suggests that NAc dopamine encodes temporal-difference (TD) errors for learning value…

Machine Learning · Computer Science 2024-11-07 Jonas Guan , Shon Eduard Verch , Claas Voelcker , Ethan C. Jackson , Nicolas Papernot , William A. Cunningham

Deep neural networks have achieved remarkable success in a wide range of classification tasks. However, they remain highly susceptible to adversarial examples - inputs that are subtly perturbed to induce misclassification while appearing…

Machine Learning · Computer Science 2025-10-20 Virendra Nishad , Bhaskar Mukhoty , Hilal AlQuabeh , Sandeep K. Shukla , Sayak Ray Chowdhury

The impressive lifelong learning in animal brains is primarily enabled by plastic changes in synaptic connectivity. Importantly, these changes are not passive, but are actively controlled by neuromodulation, which is itself under the…

Neural and Evolutionary Computing · Computer Science 2021-07-06 Thomas Miconi , Aditya Rawal , Jeff Clune , Kenneth O. Stanley

An artificial neural network can be trained by uniformly broadcasting a reward signal to units that implement a REINFORCE learning rule. Though this presents a biologically plausible alternative to backpropagation in training a network, the…

Machine Learning · Computer Science 2021-12-23 Stephen Chung

The success of deep learning sparked interest in whether the brain learns by using similar techniques for assigning credit to each synaptic weight for its contribution to the network output. However, the majority of current attempts at…

Learning depends on changes in synaptic connections deep inside the brain. In multilayer networks, these changes are triggered by error signals fed back from the output, generally through a stepwise inversion of the feedforward processing…

Neurons and Cognition · Quantitative Biology 2021-01-05 William F. Podlaski , Christian K. Machens

Deep reinforcement learning approaches have shown impressive results in a variety of different domains, however, more complex heterogeneous architectures such as world models require the different neural components to be trained separately…

Neural and Evolutionary Computing · Computer Science 2021-02-24 Sebastian Risi , Kenneth O. Stanley

Recurrent neural networks are a successful neural architecture for many time-dependent problems, including time series analysis, forecasting, and modeling of dynamical systems. Training such networks with backpropagation through time is a…

Machine Learning · Computer Science 2025-01-30 Erik Lien Bolager , Ana Cukarska , Iryna Burak , Zahra Monfared , Felix Dietrich
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