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Alzheimer's disease (AD) confirmation often relies on positron emission tomography (PET) or cerebrospinal fluid (CSF) analysis, which are costly and invasive. Consequently, structural MRI biomarkers such as cortical thickness (CT) are…

Anomaly detection for Magnetic Resonance Images (MRIs) can be solved with unsupervised methods by learning the distribution of healthy images and identifying anomalies as outliers. In presence of an additional dataset of unlabelled data…

Deep generative models have emerged as a transformative tool in medical imaging, offering substantial potential for synthetic data generation. However, recent empirical studies highlight a critical vulnerability: these models can memorize…

The Structural Similarity Index (SSIM) is generally considered to be a milestone in the recent history of Image Quality Assessment (IQA). Alas, SSIM's accepted development from the product of three heuristic factors continues to obscure…

Heterogeneity of brain diseases is a challenge for precision diagnosis/prognosis. We describe and validate Smile-GAN (SeMI-supervised cLustEring-Generative Adversarial Network), a novel semi-supervised deep-clustering method, which dissects…

Structural magnetic resonance imaging (sMRI) combined with deep learning has achieved remarkable progress in the prediction and diagnosis of Alzheimer's disease (AD). Existing studies have used CNN and transformer to build a well-performing…

The study of physiology demonstrates that the form (shape)of anatomical structures dictates their functions, and analyzing the form of anatomies plays a crucial role in clinical research. Statistical shape modeling (SSM) is a widely used…

Disentangling anatomical and contrast information from medical images has gained attention recently, demonstrating benefits for various image analysis tasks. Current methods learn disentangled representations using either paired multi-modal…

Magnetic resonance (MR) imaging is commonly used in the clinical setting to non-invasively monitor the body. There exists a large variability in MR imaging due to differences in scanner hardware, software, and protocol design. Ideally, a…

Structural magnetic resonance imaging (sMRI) can identify subtle brain changes due to its high contrast for soft tissues and high spatial resolution. It has been widely used in diagnosing neurological brain diseases, such as Alzheimer…

The traditional methods of image assessment, such as mean squared error (MSE), signal-to-noise ratio (SNR), and Peak signal-to-noise ratio (PSNR), are all based on the absolute error of images. Pearson's inner-product correlation…

Foundation segmentation models such as SAM and SAM-2 perform well on natural images but struggle with brain MRIs where structures like the caudate and thalamus lack sharp boundaries and have low contrast. Rather than fine tune these models…

Multimodal MRI provides complementary and clinically relevant information to probe tissue condition and to characterize various diseases. However, it is often difficult to acquire sufficiently many modalities from the same subject due to…

Prediction of the cognitive evolution of a person susceptible to develop a neurodegenerative disorder is crucial to provide an appropriate treatment as soon as possible. In this paper we propose a 3D siamese network designed to extract…

The ability to recover MRI signal from noise is key to achieve fast acquisition, accurate quantification, and high image quality. Past work has shown convolutional neural networks can be used with abundant and paired low and high-SNR images…

Magnetic resonance imaging (MRI) is the non-invasive modality of choice for body tissue composition analysis due to its excellent soft tissue contrast and lack of ionizing radiation. However, quantification of body composition requires an…

This paper presents a comprehensive study focused on disentangling hippocampal shape variations from diffusion tensor imaging (DTI) datasets within the context of neurological disorders. Leveraging a Mesh Variational Autoencoder (VAE)…

Purpose: This study presents a variable resolution (VR) sampling and deep learning reconstruction approach for multi-spectral MRI near metal implants, aiming to reduce scan times while maintaining image quality. Background: The rising use…

Demographic attributes such as age, sex, and race can be predicted from medical images, raising concerns about bias in clinical AI systems. In brain MRI, this signal may arise from anatomical variation, acquisition-dependent contrast…

Automated quality assessment of structural brain MRI is an important prerequisite for reliable neuroimaging analysis, but yet remains challenging due to motion artifacts and poor generalization across acquisition sites. Existing approaches…