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We consider a data-driven formulation of the classical discrete-time stochastic control problem. Our approach exploits the natural structure of many such problems, in which significant portions of the system are uncontrolled. Employing the…

Optimization and Control · Mathematics 2025-08-25 Boris Baros , Samuel N. Cohen , Christoph Reisinger

The theory of Balanced Neural Networks is a very popular explanation for the high degree of variability and stochasticity in the brain's activity. Roughly speaking, it entails that typical neurons receive many excitatory and inhibitory…

Probability · Mathematics 2025-05-27 James MacLaurin , Pedro Vilanova

This article studies the dynamics of the mean-field approximation of continuous random networks. These networks are stochastic integrodifferential equations driven by Gaussian noise. The kernels in the integral operators are realizations of…

Disordered Systems and Neural Networks · Physics 2025-02-04 W. A. Zúñiga-Galindo

This technical note introduces parametric dynamic causal modelling, a method for inferring slow changes in biophysical parameters that control fluctuations of fast neuronal states. The application domain we have in mind is inferring slow…

Quantitative Methods · Quantitative Biology 2020-08-27 Amirhossein Jafarian , Peter Zeidman , Rob. C Wykes , Matthew Walker , Karl J. Friston

We present a method for representing the closed-loop dynamics of piecewise affine (PWA) systems with bounded additive disturbances and neural network-based controllers as mixed-integer (MI) linear constraints. We show that such…

Systems and Control · Electrical Eng. & Systems 2026-05-06 Dieter Teichrib , Moritz Schulze Darup

Recent advances in experimental techniques enable the simultaneous recording of activity from thousands of neurons in the brain, presenting both an opportunity and a challenge: to build meaningful, scalable models of large neural…

Biological Physics · Physics 2025-08-05 Luca Di Carlo , Francesca Mignacco , Christopher W. Lynn , William Bialek

The computational capabilities of a neural network are widely assumed to be determined by its static architecture. Here we challenge this view by establishing that a fixed neural structure can operate in fundamentally different…

Neural and Evolutionary Computing · Computer Science 2025-09-24 Xia Chen

We present an interacting branching model of neural network dynamics, incorporating key biological features such as inhibition with several types of inhibitory interactions. We establish a hierarchy of analytical mean-field approximations…

Disordered Systems and Neural Networks · Physics 2025-12-29 Jeremy B. Goetz , Naruepon Weerawongphrom , Rashid V. Williams-García , John M. Beggs , Gerardo Ortiz

Recent whole brain imaging experiments on $\textit{C. elegans}$ has revealed that the neural population dynamics encode motor commands and stereotyped transitions between behaviors on low dimensional manifolds. Efforts to characterize the…

Quantitative Methods · Quantitative Biology 2020-04-15 Charles Fieseler , Manuel Zimmer , J. Nathan Kutz

We study neural field equations, which are prototypical models of large-scale cortical activity, subject to random data. We view this spatially-extended, nonlocal evolution equation as a Cauchy problem on abstract Banach spaces, with…

Numerical Analysis · Mathematics 2026-01-01 Daniele Avitabile , Francesca Cavallini , Svetlana Dubinkina , Gabriel J. Lord

We study a chain of non-linear, interacting spins driven by a static and a time-dependent magnetic field. The aim is to identify the conditions for the locally and temporally controlled spin switching. Analytical and full numerical…

Chaotic Dynamics · Physics 2015-05-13 L. Chotorlishvili , Z. Toklikishvili , J. Berakdar

Some biological systems operate at the critical point between stability and instability and this requires a fine-tuning of parameters. We bring together two examples from the literature that illustrate this: neural integration in the…

Optimization and Control · Mathematics 2007-05-23 Luc Moreau , Eduardo Sontag

This paper investigates recurrence properties of dynamical systems under the restriction that control is available only through inputs and outputs. We introduce the concept of ``coarse non-wandering'', a generalization of the classical…

Dynamical Systems · Mathematics 2025-09-18 Tomoo Yokoyama

Understanding the activity of large populations of neurons is difficult due to the combinatorial complexity of possible cell-cell interactions. To reduce the complexity, coarse-graining had been previously applied to experimental neural…

Neurons and Cognition · Quantitative Biology 2021-03-24 Mia C. Morrell , Audrey J. Sederberg , Ilya Nemenman

This paper introduces a framework for quantitative characterization of the controllability of time-varying linear systems (or networks) in terms of input novelty. The motivation for such an approach comes from the study of biophysical…

Optimization and Control · Mathematics 2014-11-24 Gautam Kumar , Delsin Menolascino , ShiNung Ching

Neural populations exhibit complex recurrent structures that drive behavior, while continuously receiving and integrating external inputs from sensory stimuli, upstream regions, and neurostimulation. However, neural populations are often…

Neurons and Cognition · Quantitative Biology 2025-09-24 Parsa Vahidi , Omid G. Sani , Maryam M. Shanechi

Spatiotemporal patterns such as traveling waves are frequently observed in recordings of neural activity. The mechanisms underlying the generation of such patterns are largely unknown. Previous studies have investigated the existence and…

Neurons and Cognition · Quantitative Biology 2022-09-16 Johanna Senk , Karolína Korvasová , Jannis Schuecker , Espen Hagen , Tom Tetzlaff , Markus Diesmann , Moritz Helias

We investigate stability analysis and controller design of unknown continuous-time systems under state-feedback with aperiodic sampling, using only noisy data but no model knowledge. We first derive a novel data-dependent parametrization of…

Optimization and Control · Mathematics 2022-08-26 Julian Berberich , Stefan Wildhagen , Michael Hertneck , Frank Allgöwer

Creating a quantitative theory for the cortex presents challenges and raises questions. What are the significant scales--micro, meso, or macroscopic? What are the interactions--pairwise, higher order, or mean-field? And what control…

Neurons and Cognition · Quantitative Biology 2025-05-29 Nima Dehghani

Brain aging synthesis is a critical task with broad applications in clinical and computational neuroscience. The ability to predict the future structural evolution of a subject's brain from an earlier MRI scan provides valuable insights…

Machine Learning · Computer Science 2025-08-01 Ridvan Yesiloglu , Wei Peng , Md Tauhidul Islam , Ehsan Adeli