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200 papers

Transport networks play a key role across four realms of eukaryotic life: slime molds, fungi, plants, and animals. In addition to the developmental algorithms that build them, many also employ adaptive strategies to respond to stimuli,…

Adaptation and Self-Organizing Systems · Physics 2014-06-02 Johannes Gräwer , Carl D. Modes , Marcelo O. Magnasco , Eleni Katifori

Networks of gene regulation govern morphogenesis, determine cell identity and regulate cell function. But we have little understanding, at the local level, of which logics are biologically preferred or even permitted. To solve this puzzle,…

Molecular Networks · Quantitative Biology 2022-09-02 Thomas M. A. Fink , Ryan Hannam

The study of networks plays a crucial role in investigating the structure, dynamics, and function of a wide variety of complex systems in myriad disciplines. Despite the success of traditional network analysis, standard networks provide a…

Physics and Society · Physics 2017-04-05 Manlio De Domenico , Clara Granell , Mason A. Porter , Alex Arenas

Network theory is rapidly changing our understanding of complex systems, but the relevance of topological features for the dynamic behavior of metabolic networks, food webs, production systems, information networks, or cascade failures of…

Disordered Systems and Neural Networks · Physics 2007-05-23 Dirk Helbing , Ulrich Witt , Stefan Laemmer , Thomas Brenner

The functions of many networked systems in physics, biology or engineering rely on a coordinated or synchronized dynamics of its constituents. In power grids for example, all generators must synchronize and run at the same frequency and…

Adaptation and Self-Organizing Systems · Physics 2017-09-13 Debsankha Manik , Marc Timme , Dirk Witthaut

The dynamic instability of the living systems and the "superposition" of different forms of randomness are viewed as a component of the contingently increasing organization of life along evolution. We briefly survey how classical and…

Other Quantitative Biology · Quantitative Biology 2011-04-07 Marcello Buiatti , Giuseppe Longo

Life is characterized by a myriad of complex dynamic processes allowing organisms to grow, reproduce, and evolve. Physical approaches for describing systems out of thermodynamic equilibrium have been increasingly applied to living systems,…

Biological Physics · Physics 2020-12-16 Xiaona Fang , Karsten Kruse , Ting Lu , Jin Wang

The brain is immensely complex, with diverse components and dynamic interactions building upon one another to orchestrate a wide range of functions and behaviors. Understanding patterns of these complex interactions and how they are…

Neurons and Cognition · Quantitative Biology 2024-08-06 Suman Kulkarni , Dani S. Bassett

Networked dynamical systems, i.e., systems of dynamical units coupled via nontrivial interaction topologies, constitute models of broad classes of complex systems, ranging from gene regulatory and metabolic circuits in our cells to…

Adaptation and Self-Organizing Systems · Physics 2024-03-12 Xiaozhu Zhang , Marc Timme

When considering flows in biological membranes, they are usually treated as flat, though more often than not, they are curved surfaces, even extremely curved, as in the case of the endoplasmic reticulum. Here, we study the topological…

Fluid Dynamics · Physics 2021-05-27 Rickmoy Samanta , Naomi Oppenheimer

Biological transport networks adapt through dynamic interactions between material transport and structural modification during growth and development. In this work, we present a model of transport network growth driven by local material…

Biological Physics · Physics 2025-03-27 Chanoknun Sintavanuruk , Yoichiro Mori , Reza Farhadifar , Eleni Katifori

We derive a modular fluid-flow network congestion control model based on a law of fundamental nature in networks: the conservation of information. Network elements such as queues, users, and transmission channels and network performance…

Networking and Internet Architecture · Computer Science 2016-11-18 C. Briat , E. A. Yavuz , H. Hjalmarsson , K. H. Johansson , U. T. Jönsson , G. Karlsson , H. Sandberg

Droplet formation has emerged as an essential concept for the spatiotemporal organisation of biomolecules in cells. However, classical descriptions of droplet dynamics based on passive liquid-liquid phase separation cannot capture the…

Biological Physics · Physics 2025-11-14 David Zwicker , Oliver W. Paulin , Cathelijne ter Burg

Physical networks are made of nodes and links that are physical objects embedded in a geometric space. Understanding how the mutual volume exclusion between these elements affects the structure and function of physical networks calls for a…

Statistical Mechanics · Physics 2024-06-14 Gábor Pete , Ádám Timár , Sigurdur Örn Stefánsson , Ivan Bonamassa , Márton Pósfai

Classical thermodynamics and statistical mechanics describe systems in which nothing interacts with nothing. Even the highly refined theory of simple fluids does not deal very well with electrical interactions, boundary conditions, or…

Other Quantitative Biology · Quantitative Biology 2012-08-31 Bob Eisenberg

The universal fractality of river networks is very well known, however understanding of the underlying mechanisms for them is still lacking in terms of stochastic processes. By introducing probability changing dynamically, we have described…

Statistical Mechanics · Physics 2021-04-14 Hyun-Joo Kim

As a result of a hundred million years of evolution, living animals have adapted extremely well to their ecological niche. Such adaptation implies species-specific interactions with their immediate environment by processing sensory cues and…

Disordered Systems and Neural Networks · Physics 2022-04-28 Tom Birkoben , Hermann Kohlstedt

Open flow network is a weighted directed graph with a source and a sink, depicting flux distributions on networks in the steady state of an open flow system. Energetic food webs, economic input-output networks, and international trade…

Physics and Society · Physics 2015-01-27 Liangzhu Guo , Xiaodan Lou , Peiteng Shi , Jun Wang , Xiaohan Huang , Jiang Zhang

Topological landscape is introduced for networks with functions defined on the nodes. By extending the notion of gradient flows to the network setting, critical nodes of different indices are defined. This leads to a concise and…

Methodology · Statistics 2012-05-01 E. Weinan , Jianfeng Lu , Yuan Yao

Life in complex systems, such as cities and organisms, comes to a standstill when global coordination of mass, energy, and information flows is disrupted. Global coordination is no less important in single cells, especially in large oocytes…