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Background: Elderly patients with MODS have high risk of death and poor prognosis. The performance of current scoring systems assessing the severity of MODS and its mortality remains unsatisfactory. This study aims to develop an…
Sepsis is a life-threatening disease with high morbidity, mortality and healthcare costs. The early prediction and administration of antibiotics and intravenous fluids is considered crucial for the treatment of sepsis and can save…
When exposure measurement error (EME), confounder measurement error (CME), or both are present, health effect estimates regarding exposure mixtures and critical exposure time-window may not represent the true effects. For example, in air…
Research in adversarial machine learning (AML) has shown that statistical models are vulnerable to maliciously altered data. However, despite advances in Bayesian machine learning models, most AML research remains concentrated on classical…
Trauma mortality results from a multitude of non-linear dependent risk factors including patient demographics, injury characteristics, medical care provided, and characteristics of medical facilities; yet traditional approach attempted to…
Continuous monitoring of blood oxygen saturation levels is vital for patients with pulmonary disorders. Traditionally, SpO$_2$ monitoring has been carried out using transmittance pulse oximeters due to its dependability. However, SpO$_2$…
Causal mediation analysis examines causal pathways linking exposures to disease. The estimation of interventional effects, which are mediation estimands that overcome certain identifiability problems of natural effects, has been advanced…
A typical problem in air pollution epidemiology is exposure assessment for individuals for which health data are available. Due to the sparsity of monitoring sites and the limited temporal frequency with which measurements of air pollutants…
In contrast to evaluating treatment effects, causal attribution analysis focuses on identifying the key factors responsible for an observed outcome. For two binary exposure variables and a binary outcome variable, researchers need to assess…
Referral workflow inefficiencies, including misaligned referrals and delays, contribute to suboptimal patient outcomes and higher healthcare costs. In this study, we investigated the possibility of predicting procedural needs based on…
Estimating a causal effect from observational data can be biased if we do not control for self-selection. This selection is based on confounding variables that affect the treatment assignment and the outcome. Propensity score methods aim to…
Oxidative potential (OP), which measures particulate matter's (PM) capacity to induce oxidative stress in the lungs, is increasingly recognized as an indicator of PM toxicity. Since OP is not routinely monitored, it can be challenging to…
Tobacco use remains a leading preventable contributor to serious health conditions in the United States, notably chronic obstructive pulmonary disease (COPD) and severe COVID-19 complications. Within Louisiana's Medicaid population, tobacco…
Traumatic Brain Injury (TBI) is a major contributor to mortality among older adults, with geriatric patients facing disproportionately high risk due to age-related physiological vulnerability and comorbidities. Early and accurate prediction…
Heart failure affects millions of people worldwide, significantly reducing quality of life and leading to high mortality rates. Despite extensive research, the relationship between heart failure and mortality rates among ICU patients is not…
Objective: Worldwide, heart failure (HF) is a major cause of morbidity and mortality and one of the leading causes of hospitalization. Early detection of HF symptoms and pro-active management may reduce adverse events. Approach:…
Extremely preterm infants commonly require intubation and invasive mechanical ventilation after birth. While the duration of mechanical ventilation should be minimized in order to avoid complications, extubation failure is associated with…
Background. Pre-operative risk assessments used in clinical practice are limited in their ability to identify risk for post-operative mortality. We hypothesize that electrocardiograms contain hidden risk markers that can help prognosticate…
Objective: Peritoneal Dialysis (PD) is one of the most widely used life-supporting therapies for patients with End-Stage Renal Disease (ESRD). Predicting mortality risk and identifying modifiable risk factors based on the Electronic Medical…
Few studies have linked specific sources of ambient particulate matter smaller than 2.5 $\mu$m (PM2.5) and asthma. In this study, we estimated the contributions of specific sources to PM2.5 and examined their association with daily asthma…