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As modern science becomes increasingly data-intensive, the ability to analyze and visualize large-scale, complex datasets is critical to accelerating discovery. However, many domain scientists lack the programming expertise required to…

Software Engineering · Computer Science 2025-12-01 Apu Kumar Chakroborti , Yi Ding , Lipeng Wan

The recomputability and reproducibility of results from scientific software requires access to both the source code and all associated input and output data. However, the full collection of these resources often does not accompany the key…

Computational Engineering, Finance, and Science · Computer Science 2015-12-24 Christian T. Jacobs , Alexandros Avdis , Gerard J. Gorman , Matthew D. Piggott

PyMOLfold is a flexible and open-source plugin designed to seamlessly integrate AI-based protein structure prediction and visualization within the widely used PyMOL molecular graphics system. By leveraging state-of-the-art protein folding…

Biomolecules · Quantitative Biology 2025-02-04 Colby T. Ford , Samee Ullah , Dinler Amaral Antunes , Tarsis Gesteira Ferreira

Despite image reconstruction becoming more widespread when interpreting OIFITS Data, model fitting in u,v space often remains the best way to interpret data, either because of the sparsity of the data, or because a quantitative measurement…

Instrumentation and Methods for Astrophysics · Physics 2022-07-25 Antoine Mérand

Scalable and efficient numerical simulations continue to gain importance, as computation is firmly established as the third pillar of discovery, alongside theory and experiment. Meanwhile, the performance of computing hardware grows through…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-06-26 Pietro Incardona , Antonio Leo , Yaroslav Zaluzhnyi , Rajesh Ramaswamy , Ivo F. Sbalzarini

More and more distributed software systems are being developed and deployed today. Like other software, distributed software systems also need very strong quality assurance support. Distributed software is often very large/complex, has…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-03-08 Xiaoqin Fu

We present UMI-3D, a multimodal extension of the Universal Manipulation Interface (UMI) for robust and scalable data collection in embodied manipulation. While UMI enables portable, wrist-mounted data acquisition, its reliance on monocular…

Robotics · Computer Science 2026-04-16 Ziming Wang

The advancements in data acquisition, storage, and processing techniques have resulted in the rapid growth of heterogeneous medical data. Integrating radiological scans, histopathology images, and molecular information with clinical data is…

Machine Learning · Computer Science 2023-12-25 Aakash Tripathi , Asim Waqas , Kavya Venkatesan , Yasin Yilmaz , Ghulam Rasool

Event-based multimodal large language models (MLLMs) enable robust perception in high-speed and low-light scenarios, addressing key limitations of frame-based MLLMs. However, current event-based MLLMs often rely on dense image-like…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Shaoyu Liu , Jianing Li , Guanghui Zhao , Yunjian Zhang , Wen Jiang , Ming Li , Xiangyang Ji

Large Language Models (LLMs) power numerous AI applications, yet updating their knowledge remains costly. Model editing provides a lightweight alternative through targeted parameter modifications, with meta-learning-based model editing…

Computation and Language · Computer Science 2026-01-30 Xiaopeng Li , Shasha Li , Xi Wang , Shezheng Song , Bin Ji , Shangwen Wang , Jun Ma , Xiaodong Liu , Mina Liu , Jie Yu

Any data analysis, especially the data sets that may be changing often or in real-time, consists of at least three important synchronized components: i) figuring out what to infer (objectives), ii) analysis or computation of objectives, and…

Human-Computer Interaction · Computer Science 2021-06-11 Abhishek Santra , Kunal Samant , Endrit Memeti , Enamul Karim , Sharma Chakravarthy

Enhancing sampling and analyzing simulations are central issues in molecular simulation. Recently, we introduced PLUMED, an open-source plug-in that provides some of the most popular molecular dynamics (MD) codes with implementations of a…

Computational Physics · Physics 2014-10-07 Gareth A. Tribello , Massimiliano Bonomi , Davide Branduardi , Carlo Camilloni , Giovanni Bussi

Evaluating the performance of Multi-modal Large Language Models (MLLMs), integrating both point cloud and language, presents significant challenges. The lack of a comprehensive assessment hampers determining whether these models truly…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 Junjie Zhang , Tianci Hu , Xiaoshui Huang , Yongshun Gong , Dan Zeng

Phylogenetic analysis, which allow to understand the evolution of bacterial and viral epidemics, requires large quantities of data to be analysed and processed for knowledge extraction. One of the major challenges consists on the…

Populations and Evolution · Quantitative Biology 2024-05-28 Nyckollas Brandão , André Jesus , André Páscoa , Alexandre P. Francisco , Mário Ramirez , Cátia Vaz

The recent development and success of Large Language Models (LLMs) necessitate an evaluation of their performance across diverse NLP tasks in different languages. Although several frameworks have been developed and made publicly available,…

This paper presents hep-aid, a modular Python library conceived for utilising, implementing, and developing parameter scan algorithms. Originally devised for sample-efficient, multi-objective active search approaches in computationally…

High Energy Physics - Phenomenology · Physics 2024-12-24 Mauricio A. Diaz , Srinandan Dasmahapatra , Stefano Moretti

The freud Python package is a powerful library for analyzing simulation data. Written with modern simulation and data analysis workflows in mind, freud provides a Python interface to fast, parallelized C++ routines that run efficiently on…

Modern sparse language models typically achieve sparsity through Mixture-of-Experts (MoE) layers, which dynamically route tokens to dense MLP "experts." However, dynamic hard routing has a number of drawbacks, such as potentially poor…

Machine Learning · Computer Science 2026-02-02 Albert Tseng , Christopher De Sa

3D medical image classification is essential for modern clinical workflows. Medical foundation models (FMs) have emerged as a promising approach for scaling to new tasks, yet current research suffers from three critical pitfalls:…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Han Liu , Bogdan Georgescu , Yanbo Zhang , Youngjin Yoo , Michael Baumgartner , Riqiang Gao , Jianing Wang , Gengyan Zhao , Eli Gibson , Dorin Comaniciu , Sasa Grbic

Stellar abundance analysis relies on flexible, high-performance spectral synthesis. To meet these needs, we present PySME v1.0, an updated Python implementation of Spectroscopy Made Easy (SME) designed for precise and survey-scale modelling…

Instrumentation and Methods for Astrophysics · Physics 2026-05-12 Mingjie Jian , Nikolai Piskunov , Jeff Valenti , Ella Xi Wang , Brian Thorsbro , Henrik Jönsson , Ansgar Wehrhahn