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Interpretability is significant in computational pathology, leading to the development of multimodal information integration from histopathological image and corresponding text data.However, existing multimodal methods have limited…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Kangcheng Zhou , Jun Jiang , Qing Zhang , Shuang Zheng , Qingli Li , Shugong Xu

A distinguishing feature of a multicellular living system is that it operates at various scales, from the intracellular to organismal. Very little is known at present on how tissue level properties are related to cell and subcellular…

Biological Physics · Physics 2007-06-26 Elijah Flenner , Francoise Marga , Adrian Neagu , Ioan Kosztin , Gabor Forgacs

Primary liver malignancies are widely recognized as the most heterogeneous and prognostically diverse cancers of the digestive system. Among these, hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) emerge as the two…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Anwen Lu , Mingxin Liu , Yiping Jiao , Hongyi Gong , Geyang Xu , Jun Chen , Jun Xu

Weakly supervised image segmentation with image-level labels has drawn attention due to the high cost of pixel-level annotations. Traditional methods using Class Activation Maps (CAMs) often highlight only the most discriminative regions,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Qingchen Tang , Lei Fan , Maurice Pagnucco , Yang Song

Whole Slide Imaging (WSI) has become a gold standard in cancer diagnosis, inspecting multi-scale information from cellular to tissue levels. Processing an entire WSI directly is infeasible due to GPU memory constraints; thus, Multiple…

Image and Video Processing · Electrical Eng. & Systems 2026-05-08 Tianyi Zhang , Sicheng Chen , Borui Kang , Dankai Liao , Qiaochu Xue , Bochong Zhang , Fei Xia , Zeyu Liu , Yueming Jin

Cross-modal retrieval is gaining increasing efficacy and interest from the research community, thanks to large-scale training, novel architectural and learning designs, and its application in LLMs and multimodal LLMs. In this paper, we move…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Davide Caffagni , Sara Sarto , Marcella Cornia , Lorenzo Baraldi , Rita Cucchiara

In digital pathology, both detection and classification of cells are important for automatic diagnostic and prognostic tasks. Classifying cells into subtypes, such as tumor cells, lymphocytes or stromal cells is particularly challenging.…

Computer Vision and Pattern Recognition · Computer Science 2022-06-07 Shahira Abousamra , David Belinsky , John Van Arnam , Felicia Allard , Eric Yee , Rajarsi Gupta , Tahsin Kurc , Dimitris Samaras , Joel Saltz , Chao Chen

Recent advances in multi-modal detection have significantly improved detection accuracy in challenging environments (e.g., low light, overexposure). By integrating RGB with modalities such as thermal and depth, multi-modal fusion increases…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Xiaofan Yang , Yubin Liu , Wei Pan , Guoqing Chu , Junming Zhang , Jie Zhao , Zhuoqi Man , Xuanming Cao

Histological subtype of papillary (p) renal cell carcinoma (RCC), type 1 vs. type 2, is an essential prognostic factor. The two subtypes of pRCC have a similar pattern, i.e., the papillary architecture, yet some subtle differences,…

Computer Vision and Pattern Recognition · Computer Science 2021-06-24 Zeyu Gao , Bangyang Hong , Xianli Zhang , Yang Li , Chang Jia , Jialun Wu , Chunbao Wang , Deyu Meng , Chen Li

Supervised learning has been widely used for attack categorization, requiring high-quality data and labels. However, the data is often imbalanced and it is difficult to obtain sufficient annotations. Moreover, supervised models are subject…

Cryptography and Security · Computer Science 2022-09-05 Zihan Li , Wentao Chen , Zhiqing Wei , Xingqi Luo , Bing Su

Motivation: Tumor classification using Imaging Mass Spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are…

Machine Learning · Statistics 2018-06-28 Jens Behrmann , Christian Etmann , Tobias Boskamp , Rita Casadonte , Jörg Kriegsmann , Peter Maass

Microscopic examination of tissues or histopathology is one of the diagnostic procedures for detecting colorectal cancer. The pathologist involved in such an examination usually identifies tissue type based on texture analysis, especially…

Image and Video Processing · Electrical Eng. & Systems 2020-04-06 Srinath Jayachandran , Ashlin Ghosh

Histopathology has played an essential role in cancer diagnosis. With the rapid advances in convolutional neural networks (CNN). Various CNN-based automated pathological image segmentation approaches have been developed in computer-assisted…

Image and Video Processing · Electrical Eng. & Systems 2021-09-23 Cam Nguyen , Zuhayr Asad , Yuankai Huo

Novel multimodal imaging methods are capable of generating extensive, super high resolution datasets for preclinical research. Yet, a massive lack of annotations prevents the broad use of deep learning to analyze such data. So far, existing…

Image and Video Processing · Electrical Eng. & Systems 2021-04-26 Izabela Horvath , Johannes C. Paetzold , Oliver Schoppe , Rami Al-Maskari , Ivan Ezhov , Suprosanna Shit , Hongwei Li , Ali Ertuerk , Bjoern H. Menze

Many visual scenes contain text that carries crucial information, and it is thus essential to understand text in images for downstream reasoning tasks. For example, a deep water label on a warning sign warns people about the danger in the…

Computer Vision and Pattern Recognition · Computer Science 2020-03-26 Ronghang Hu , Amanpreet Singh , Trevor Darrell , Marcus Rohrbach

An important goal of medical imaging is to be able to precisely detect patterns of disease specific to individual scans; however, this is challenged in brain imaging by the degree of heterogeneity of shape and appearance. Traditional…

Purpose: Surgery scene understanding with tool-tissue interaction recognition and automatic report generation can play an important role in intra-operative guidance, decision-making and postoperative analysis in robotic surgery. However,…

Artificial Intelligence · Computer Science 2022-11-29 Lalithkumar Seenivasan , Mobarakol Islam , Mengya Xu , Chwee Ming Lim , Hongliang Ren

Definitive cancer diagnosis and management depend upon the extraction of information from microscopy images by pathologists. These images contain complex information requiring time-consuming expert human interpretation that is prone to…

[18F]-Fluorodeoxyglucose (FDG) positron emission tomography - computed tomography (PET-CT) has become the imaging modality of choice for diagnosing many cancers. Co-learning complementary PET-CT imaging features is a fundamental requirement…

Image and Video Processing · Electrical Eng. & Systems 2023-08-08 Lei Bi , Michael Fulham , Shaoli Song , David Dagan Feng , Jinman Kim

Non-coding RNAs (ncRNAs) play pivotal roles in gene expression regulation and the pathogenesis of various diseases. Accurate classification of ncRNAs is essential for functional annotation and disease diagnosis. To address existing…

Machine Learning · Computer Science 2025-09-25 Xin An , Ruijie Li , Qiao Ning , Hui Li , Qian Ma , Shikai Guo
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