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Deep learning integration into medical imaging systems has transformed disease detection and diagnosis processes with a focus on pneumonia identification. The study introduces an intricate deep learning system using Convolutional Neural…

Image and Video Processing · Electrical Eng. & Systems 2025-10-02 P K Dutta , Anushri Chowdhury , Anouska Bhattacharyya , Shakya Chakraborty , Sujatra Dey

Deployments of artificial intelligence in medical diagnostics mandate not just accuracy and efficacy but also trust, emphasizing the need for explainability in machine decisions. The recent trend in automated medical image diagnostics leans…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Ugur Demir , Debesh Jha , Zheyuan Zhang , Elif Keles , Bradley Allen , Aggelos K. Katsaggelos , Ulas Bagci

In the last two decades Computer Aided Diagnostics (CAD) systems were developed to help radiologists analyze screening mammograms. The benefits of current CAD technologies appear to be contradictory and they should be improved to be…

Computer Vision and Pattern Recognition · Computer Science 2017-11-10 Dezső Ribli , Anna Horváth , Zsuzsa Unger , Péter Pollner , István Csabai

Objective: Radiomics-driven Computer Aided Diagnosis (CAD) has shown considerable promise in recent years as a potential tool for improving clinical decision support in medical oncology, particularly those based around the concept of…

Artificial Intelligence · Computer Science 2017-10-31 Devinder Kumar , Graham W. Taylor , Alexander Wong

Current approaches to explaining the decisions of deep learning systems for medical tasks have focused on visualising the elements that have contributed to each decision. We argue that such approaches are not enough to "open the black box"…

Artificial Intelligence · Computer Science 2018-06-04 William Gale , Luke Oakden-Rayner , Gustavo Carneiro , Andrew P Bradley , Lyle J Palmer

Existing deep learning models for chest radiology often neglect patient metadata, limiting diagnostic accuracy and fairness. To bridge this gap, we introduce MetaCheX, a novel multimodal framework that integrates chest X-ray images with…

Image and Video Processing · Electrical Eng. & Systems 2025-09-17 Nathan He , Cody Chen

Objective. This paper presents an overview of generalizable and explainable artificial intelligence (XAI) in deep learning (DL) for medical imaging, aimed at addressing the urgent need for transparency and explainability in clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Ahmad Chaddad , Yan Hu , Yihang Wu , Binbin Wen , Reem Kateb

The chest X-ray (CXR) is by far the most commonly performed radiological examination for screening and diagnosis of many cardiac and pulmonary diseases. There is an immense world-wide shortage of physicians capable of providing rapid and…

Computer Vision and Pattern Recognition · Computer Science 2018-06-07 Jonathan Laserson , Christine Dan Lantsman , Michal Cohen-Sfady , Itamar Tamir , Eli Goz , Chen Brestel , Shir Bar , Maya Atar , Eldad Elnekave

The clinical adoption of artificial intelligence (AI) in medical imaging requires models that are both diagnostically accurate and interpretable to clinicians. While current multimodal biomedical foundation models prioritize performance,…

Natural language explanations provide an inherently human-understandable way to explain black-box models, closely reflecting how radiologists convey their diagnoses in textual reports. Most works explicitly supervise the explanation…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Isabel Rio-Torto , Jaime S. Cardoso , Luís F. Teixeira

Self-supervised learning (SSL) has emerged as a powerful paradigm for Chest X-ray (CXR) analysis under limited annotations. Yet, existing SSL strategies remain suboptimal for medical imaging. Masked image modeling allocates substantial…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Wangyu Feng , Shawn Young , Lijian Xu

Supervised machine learning classifiers sometimes face challenges related to the performance, accuracy, or overfitting. This paper introduces the Artificial Liver Classifier (ALC), a novel supervised learning model inspired by the human…

Artificial Intelligence · Computer Science 2025-09-24 Mahmood A. Jumaah , Yossra H. Ali , Tarik A. Rashid

Purpose: Interpreting chest radiographs (CXR) remains challenging due to the ambiguity of overlapping structures such as the lungs, heart, and bones. To address this issue, we propose a novel method for extracting fine-grained anatomical…

Image and Video Processing · Electrical Eng. & Systems 2023-06-08 Constantin Seibold , Alexander Jaus , Matthias A. Fink , Moon Kim , Simon Reiß , Ken Herrmann , Jens Kleesiek , Rainer Stiefelhagen

Interpretability is often an essential requirement in medical imaging. Advanced deep learning methods are required to address this need for explainability and high performance. In this work, we investigate whether additional information…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Luisa Gallee , Meinrad Beer , Michael Goetz

Interpretability in machine learning models is important in high-stakes decisions, such as whether to order a biopsy based on a mammographic exam. Mammography poses important challenges that are not present in other computer vision tasks:…

Machine Learning · Computer Science 2021-03-24 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

Chest X-rays (CXRs) often display various diseases with disparate class frequencies, leading to a long-tailed, multi-label data distribution. In response to this challenge, we explore the Pruned MIMIC-CXR-LT dataset, a curated collection…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Chin-Wei Huang , Mu-Yi Shen , Kuan-Chang Shih , Shih-Chih Lin , Chi-Yu Chen , Po-Chih Kuo

Medical image classification is a critical problem for healthcare, with the potential to alleviate the workload of doctors and facilitate diagnoses of patients. However, two challenges arise when deploying deep learning models to real-world…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 An Yan , Yu Wang , Yiwu Zhong , Zexue He , Petros Karypis , Zihan Wang , Chengyu Dong , Amilcare Gentili , Chun-Nan Hsu , Jingbo Shang , Julian McAuley

Developing an interpretable system for generating reports in chest X-ray (CXR) analysis is becoming increasingly crucial in Computer-aided Diagnosis (CAD) systems, enabling radiologists to comprehend the decisions made by these systems.…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Trong Thang Pham , Ngoc-Vuong Ho , Nhat-Tan Bui , Thinh Phan , Patel Brijesh , Donald Adjeroh , Gianfranco Doretto , Anh Nguyen , Carol C. Wu , Hien Nguyen , Ngan Le

Deep learning has demonstrated expert-level performance in melanoma classification, positioning it as a powerful tool in clinical dermatology. However, model opacity and the lack of interpretability remain critical barriers to clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Junwen Zheng , Xinran Xu , Li Rong Wang , Chang Cai , Lucinda Siyun Tan , Dingyuan Wang , Hong Liang Tey , Xiuyi Fan

Interpretability is essential in medical imaging to ensure that clinicians can comprehend and trust artificial intelligence models. In this paper, we propose a novel interpretable approach that combines attribute regularization of the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-15 Maxime Di Folco , Cosmin I. Bercea , Julia A. Schnabel