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The advent of deep learning has significantly propelled the capabilities of automated medical image diagnosis, providing valuable tools and resources in the realm of healthcare and medical diagnostics. This research delves into the…

Image and Video Processing · Electrical Eng. & Systems 2023-11-20 Ryan Donghan Kwon , Dohyun Lim , Yoonha Lee , Seung Won Lee

Concept Bottleneck Models (CBMs) in medical imaging aim to improve model interpretability by predicting intermediate clinical concepts before final diagnoses. However, most existing CBMs treat concepts as discriminative predictors of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Amy Rafferty , Rishi Ramaesh , Ajitha Rajan

Chest X ray (CXR) imaging remains a critical diagnostic tool for thoracic conditions, but current automated systems face limitations in pathology coverage, diagnostic accuracy, and integration of visual and textual reasoning. To address…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 Wenting Chen , Yi Dong , Zhaojun Ding , Yucheng Shi , Yifan Zhou , Fang Zeng , Yijun Luo , Tianyu Lin , Yihang Su , Yichen Wu , Kai Zhang , Zhen Xiang , Tianming Liu , Ninghao Liu , Lichao Sun , Yixuan Yuan , Xiang Li

CLIP and BiomedCLIP are examples of vision-language foundation models and offer strong cross-modal embeddings; however, they are not optimized for fine-grained medical retrieval tasks, such as retrieving clinically relevant radiology…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Zhaohui Liang , Sivaramakrishnan Rajaraman , Niccolo Marini , Zhiyun Xue , Sameer Antani

Chest X-rays (CXRs) are among the most commonly used medical image modalities. They are mostly used for screening, and an indication of disease typically results in subsequent tests. As this is mostly a screening test used to rule out chest…

Computer Vision and Pattern Recognition · Computer Science 2019-04-04 Ken C. L. Wong , Mehdi Moradi , Joy Wu , Tanveer Syeda-Mahmood

Thoracic diseases are very serious health problems that plague a large number of people. Chest X-ray is currently one of the most popular methods to diagnose thoracic diseases, playing an important role in the healthcare workflow. However,…

Computer Vision and Pattern Recognition · Computer Science 2018-11-09 Chengsheng Mao , Yiheng Pan , Zexian Zeng , Liang Yao , Yuan Luo

Black-box deep learning approaches have showcased significant potential in the realm of medical image analysis. However, the stringent trustworthiness requirements intrinsic to the medical field have catalyzed research into the utilization…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Yequan Bie , Luyang Luo , Hao Chen

Objective: Lung cancer is the leading cause of cancer-related death worldwide. Computer-aided diagnosis (CAD) systems have shown significant promise in recent years for facilitating the effective detection and classification of abnormal…

Computer Vision and Pattern Recognition · Computer Science 2019-01-16 Vignesh Sankar , Devinder Kumar , David A. Clausi , Graham W. Taylor , Alexander Wong

Deep Learning (DL) holds enormous potential for improving medical imaging diagnostics, yet the lack of interpretability in most models hampers clinical trust and adoption. This paper presents an explainable deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Sai Teja Erukude , Viswa Chaitanya Marella , Suhasnadh Reddy Veluru

Radiomics-based AI models show promise for breast cancer diagnosis but often lack interpretability, limiting clinical adoption. This study addresses the gap between radiomic features (RF) and the standardized BI-RADS lexicon by proposing a…

Radiomics analysis has achieved great success in recent years. However, conventional Radiomics analysis suffers from insufficiently expressive hand-crafted features. Recently, emerging deep learning techniques, e.g., convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Jiancheng Yang , Rongyao Fang , Bingbing Ni , Yamin Li , Yi Xu , Linguo Li

Accurate and interpretable survival analysis remains a core challenge in oncology. With growing multimodal data and the clinical need for transparent models to support validation and trust, this challenge increases in complexity. We propose…

Artificial Intelligence · Computer Science 2025-09-29 Mafalda Malafaia , Peter A. N. Bosman , Coen Rasch , Tanja Alderliesten

IMACT-CXR is an interactive multi-agent conversational tutor that helps trainees interpret chest X-rays by unifying spatial annotation, gaze analysis, knowledge retrieval, and image-grounded reasoning in a single AutoGen-based workflow. The…

Artificial Intelligence · Computer Science 2026-04-17 Tuan-Anh Le , Anh Mai Vu , David Yang , Akash Awasthi , Hien Van Nguyen

Chest X-ray (CXR) interpretation is a fundamental yet complex clinical task that increasingly relies on artificial intelligence for automation. However, traditional monolithic models often lack the nuanced reasoning required for trustworthy…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Shawn Young , Lijian Xu

Deep learning methods, in particular convolutional neural networks, have emerged as a powerful tool in medical image computing tasks. While these complex models provide excellent performance, their black-box nature may hinder real-world…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Yuzhe Lu , Adam Perer

Chest X-ray radiography (CXR) is an essential medical imaging technique for disease diagnosis. However, as 2D projectional images, CXRs are limited by structural superposition and hence fail to capture 3D anatomies. This limitation makes…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Zefan Yang , Ge Wang , James Hendler , Mannudeep K. Kalra , Pingkun Yan

Artificial intelligence (AI) is disrupting the medical field as advances in modern technology allow common household computers to learn anatomical and pathological features that distinguish between healthy and disease with the accuracy of…

Image and Video Processing · Electrical Eng. & Systems 2022-01-03 Alexandrea K. Ramnarine

Chest X-ray (CXR) is perhaps the most frequently-performed radiological investigation globally. In this work, we present and study several machine learning approaches to develop automated CXR diagnostic models. In particular, we trained…

Computer Vision and Pattern Recognition · Computer Science 2021-05-10 Edoardo Giacomello , Pier Luca Lanzi , Daniele Loiacono , Luca Nassano

The interpretability of deep neural networks has become a subject of great interest within the medical and healthcare domain. This attention stems from concerns regarding transparency, legal and ethical considerations, and the medical…

Image and Video Processing · Electrical Eng. & Systems 2023-11-20 Mahbub Ul Alam , Jaakko Hollmén , Jón Rúnar Baldvinsson , Rahim Rahmani

Expert radiologists visually scan Chest X-Ray (CXR) images, sequentially fixating on anatomical structures to perform disease diagnosis. An automatic multi-label classifier of diseases in CXR images can benefit by incorporating aspects of…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Ashish Verma , Aupendu Kar , Krishnendu Ghosh , Sobhan Kanti Dhara , Debashis Sen , Prabir Kumar Biswas