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Generative Design (GD) combines artificial intelligence (AI), physics-based modeling, and multi-objective optimization to autonomously explore and refine engineering designs. Despite its promise in aerospace, automotive, and other…

Computational Engineering, Finance, and Science · Computer Science 2025-11-24 Sergio Torregrosa , David Munoz , Hector Navarro , Charbel Farhat , Francisco Chinesta

In chemical process engineering, surrogate models of complex systems are often necessary for tasks of domain exploration, sensitivity analysis of the design parameters, and optimization. A suite of computational fluid dynamics (CFD)…

Computational Engineering, Finance, and Science · Computer Science 2020-09-09 Gabriel F. N. Gonçalves , Assen Batchvarov , Yuyi Liu , Yuxin Liu , Lachlan Mason , Indranil Pan , Omar K. Matar

Excessive loads near wounds produce pathological scarring and other complications. Presently, stress cannot easily be measured by surgeons in the operating room. Instead, surgeons rely on intuition and experience. Predictive computational…

Medical Physics · Physics 2020-10-07 Casey Stowers , Taeksang Lee , Ilias Bilionis , Arun Gosain , Adrian Buganza Tepole

Deep geological repositories are critical for the long-term storage of hazardous materials, where understanding the mechanical behavior of emplacement drifts is essential for safety assurance. This study presents a surrogate modeling…

Molecular discovery within the vast chemical space remains a significant challenge due to the immense number of possible molecules and limited scalability of conventional screening methods. To approach chemical space exploration more…

Chemical Physics · Physics 2025-07-16 Luis J. Walter , Tristan Bereau

As we aim to control complex systems, use of a simulator in model-based reinforcement learning is becoming more common. However, it has been challenging to overcome the Reality Gap, which comes from nonlinear model bias and susceptibility…

Robotics · Computer Science 2017-05-16 Gilwoo Lee , Siddhartha S. Srinivasa , Matthew T. Mason

Stiff ordinary differential equations (ODEs) play an important role in many scientific and engineering applications. Often, the dependence of the solution of the ODE on additional parameters is of interest, e.g.\ when dealing with…

Numerical Analysis · Mathematics 2025-11-11 Idoia Cortes Garcia , P. Förster , W. Schilders , S. Schöps

Optimal transport (OT) has emerged as a fundamental tool in modern machine learning, yet its computational cost remains a significant bottleneck for large-scale applications. While harnessing the massive parallelism of modern GPU hardware…

Mathematical Software · Computer Science 2026-05-12 Yixuan Qiu

Bayesian hyperparameter optimization relies heavily on Gaussian Process (GP) surrogates, due to robust distributional posteriors and strong performance on limited training samples. GPs however underperform in categorical hyperparameter…

Machine Learning · Computer Science 2025-09-23 Riccardo Doyle

Gaussian Processes (GPs) are expressive models for capturing signal statistics and expressing prediction uncertainty. As a result, the robotics community has gathered interest in leveraging these methods for inference, planning, and…

Robotics · Computer Science 2023-08-29 Francesco Crocetti , Jeffrey Mao , Alessandro Saviolo , Gabriele Costante , Giuseppe Loianno

The exact quantum dynamics of lattice models can be computationally intensive, especially when aiming for large system sizes and extended simulation times necessary to converge transport coefficients. By leveraging finite memory times to…

Chemical Physics · Physics 2024-11-14 Srijan Bhattacharyya , Thomas Sayer , Andrés Montoya-Castillo

The characterization of nanostructued materials under reactive environments is challenging due to the complexity of the structural motifs involved and their chemical transformations. Global optimization approaches allow predicting stable…

Gaussian process (GP) emulator has been used as a surrogate model for predicting force field and molecular potential, to overcome the computational bottleneck of molecular dynamics simulation. Integrating both atomic force and energy in…

Chemical Physics · Physics 2022-05-13 Hao Li , Musen Zhou , Jessalyn Sebastian , Jianzhong Wu , Mengyang Gu

For developing innovative systems architectures, modeling and optimization techniques have been central to frame the architecting process and define the optimization and modeling problems. In this context, for system-of-systems the use of…

Artificial Intelligence · Computer Science 2026-05-07 Paul Saves , Jasper Bussemaker , Rémi Lafage , Thierry Lefebvre , Nathalie Bartoli , Youssef Diouane , Joseph Morlier

This paper proposes novel noise-free Bayesian optimization strategies that rely on a random exploration step to enhance the accuracy of Gaussian process surrogate models. The new algorithms retain the ease of implementation of the classical…

Machine Learning · Computer Science 2024-07-18 Hwanwoo Kim , Daniel Sanz-Alonso

By enabling constraint-aware online model adaptation, model predictive control using Gaussian process (GP) regression has exhibited impressive performance in real-world applications and received considerable attention in the learning-based…

Optimization and Control · Mathematics 2024-09-17 Amon Lahr , Andrea Zanelli , Andrea Carron , Melanie N. Zeilinger

Public-transit systems face a number of operational challenges: (a) changing ridership patterns requiring optimization of fixed line services, (b) optimizing vehicle-to-trip assignments to reduce maintenance and operation codes, and (c)…

Systems and Control · Electrical Eng. & Systems 2021-07-02 Ruixiao Sun , Rongze Gui , Himanshu Neema , Yuche Chen , Juliette Ugirumurera , Joseph Severino , Philip Pugliese , Aron Laszka , Abhishek Dubey

Accurate simulation of atomic systems has the potential to revolutionize the design of molecules and materials. Unfortunately, exact solutions of the Schr\"odinger equation scale as O(N!) and remain inaccessible for systems with more than a…

Physics phenomena are often described by ordinary and/or partial differential equations (ODEs/PDEs), and solved analytically or numerically. Unfortunately, many real-world systems are described only approximately with missing or unknown…

Machine Learning · Statistics 2025-06-30 Gurjeet Sangra Singh , Maciej Falkiewicz , Alexandros Kalousis

Simulations of quantum transport in coherent conductors have evolved into mature techniques that are used in fields of physics ranging from electrical engineering to quantum nanoelectronics and material science. The most efficient…

Mesoscale and Nanoscale Physics · Physics 2019-12-25 Mathieu Istas , Christoph Groth , Xavier Waintal