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Artificial neural networks face the stability-plasticity dilemma in continual learning, while the brain can maintain memories and remain adaptable. However, the biological strategies for continual learning and their potential to inspire…

Machine Learning · Computer Science 2025-02-04 Heming Zou , Yunliang Zang , Xiangyang Ji

Continual learning in computational systems is challenging due to catastrophic forgetting. We discovered a two layer neural circuit in the fruit fly olfactory system that addresses this challenge by uniquely combining sparse coding and…

Machine Learning · Computer Science 2021-12-23 Yang Shen , Sanjoy Dasgupta , Saket Navlakha

The insect olfactory system, which includes the antennal lobe (AL), mushroom body (MB), and ancillary structures, is a relatively simple neural system capable of learning. Its structural features, which are widespread in biological neural…

Neurons and Cognition · Quantitative Biology 2018-02-09 Charles B. Delahunt , Jeffrey A. Riffell , J. Nathan Kutz

Recordings from neurons in the insects' olfactory primary processing center, the antennal lobe (AL), reveal that the AL is able to process the input from chemical receptors into distinct neural activity patterns, called olfactory neural…

Neurons and Cognition · Quantitative Biology 2014-08-27 Eli Shlizerman , Jeffrey A. Riffell , J. Nathan Kutz

Animals smelling in the real world use a small number of receptors to sense a vast number of natural molecular mixtures, and proceed to learn arbitrary associations between odors and valences. Here, we propose a new interpretation of how…

Neurons and Cognition · Quantitative Biology 2017-07-10 Kamesh Krishnamurthy , Ann M Hermundstad , Thierry Mora , Aleksandra M Walczak , Vijay Balasubramanian

We present a model of an olfactory system that performs odor segmentation. Based on the anatomy and physiology of natural olfactory systems, it consists of a pair of coupled modules, bulb and cortex. The bulb encodes the odor inputs as…

Disordered Systems and Neural Networks · Physics 2007-05-23 Zhaoping Li , John Hertz

Studies of insect olfactory processing indicate that odors are represented by rich spatio-temporal patterns of neural activity. These patterns are very difficult to predict a priori, yet they are stimulus specific and reliable upon repeated…

Neurons and Cognition · Quantitative Biology 2007-05-23 M. I. Rabinovich , R. Huerta , A. Volkovskii , Henry D. I. Abarbanel , G. Laurent

We present a neural algorithm for the rapid online learning and identification of odorant samples under noise, based on the architecture of the mammalian olfactory bulb and implemented on the Intel Loihi neuromorphic system. As with…

Neural and Evolutionary Computing · Computer Science 2020-05-26 Nabil Imam , Thomas A. Cleland

The reshaping and decorrelation of similar activity patterns by neuronal networks can enhance their discriminability, storage, and retrieval. How can such networks learn to decorrelate new complex patterns, as they arise in the olfactory…

Neurons and Cognition · Quantitative Biology 2015-06-04 Siu-Fai Chow , Stuart D. Wick , Hermann Riecke

We present a novel machine learning architecture for classification suggested by experiments on olfactory systems. The network separates input stimuli, represented as spatially distinct currents, via winnerless competition---a process based…

Biological Physics · Physics 2020-06-18 Jason A. Platt , Anna Miller , Lawson Fuller , Henry D. I. Abarbanel

Living systems continually respond to signals from the surrounding environment. Survival requires that their responses adapt quickly and robustly to the changes in the environment. One particularly challenging example is olfactory…

Neurons and Cognition · Quantitative Biology 2024-10-08 Kiri Choi , Will Rosenbluth , Isabella R. Graf , Nirag Kadakia , Thierry Emonet

The mammalian olfactory system learns rapidly from very few examples, presented in unpredictable online sequences, and then recognizes these learned odors under conditions of substantial interference without exhibiting catastrophic…

Neural and Evolutionary Computing · Computer Science 2019-07-15 Ayon Borthakur , Thomas A. Cleland

Trial-and-error learning requires evaluating variable actions and reinforcing successful variants. In songbirds, vocal exploration is induced by LMAN, the output of a basal ganglia-circuit that also contributes a corrective bias to the…

Neurons and Cognition · Quantitative Biology 2017-03-09 Tiberiu Tesileanu , Bence Ölveczky , Vijay Balasubramanian

Olfaction sensing in autonomous robotics faces challenges in dynamic operations, energy efficiency, and edge processing. It necessitates a machine learning algorithm capable of managing real-world odor interference, ensuring resource…

Signal Processing · Electrical Eng. & Systems 2024-07-09 Rizwana Kausar , Fakhreddine Zayer , Jaime Viegas , Jorge Dias

The Drosophila mushroom body (MB) is known to be involved in olfactory learning and memory; the synaptic plasticity of the Kenyon cell (KC) to mushroom body output neuron (MBON) synapses plays a key role in the learning process. Previous…

Neurons and Cognition · Quantitative Biology 2025-09-25 Katherine Xie , Gabriel Koch Ocker

This study investigates the dynamics of non-spatial specializations in hippocampal place cells during exposure to novel environments. Hippocampal place cells, known for their role in spatial mapping, exhibit multi-modal responses to sensory…

We present a model of a coupled system of the olfactory bulb and cortex. Odor inputs to the epithelium are transformed to oscillatory bulbar activities. The cortex recognizes the odor by resonating to the bulbar oscillating pattern when the…

Biological Physics · Physics 2007-05-23 Zhaoping Li , John Hertz

The olfactory sense measures the chemical composition of the environment using a diverse array of olfactory receptors. In vertebrates, the olfactory receptors reside in a mucus layer in the nasal cavity and can thus only detect odorants…

Biological Physics · Physics 2023-01-25 Swati Sen , David Zwicker

In the principal cells of the insect mushroom body, the Kenyon cells (KC), olfactory information is represented by a spatially and temporally sparse code. Each odor stimulus will activate only a small portion of neurons and each stimulus…

Biological Physics · Physics 2010-07-21 Farzad Farkhooi , Eilif Muller , Martin P. Nawrot

Fruit flies are established model systems for studying olfactory learning as they will readily learn to associate odors with both electric shock or sugar rewards. The mechanisms of the insect brain apparently responsible for odor learning…

Machine Learning · Computer Science 2025-01-09 Jinyung Hong , Theodore P. Pavlic
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