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Dynamic positron emission tomography (PET) imaging combined with radiotracer kinetic modeling is a powerful technique for visualizing biological processes in the brain, offering valuable insights into brain functions and neurological…

Image and Video Processing · Electrical Eng. & Systems 2025-11-26 Junyu Chen , Zirui Jiang , Jennifer M. Coughlin , Ian Cheong , Kelly A. Mills , Martin G. Pomper , Yong Du

Dynamic positron emission tomography (PET) and kinetic modeling are pivotal in advancing tracer development research in small animal studies. Accurate kinetic modeling requires precise input function estimation, traditionally achieved via…

Accurate kinetic analysis of [$^{18}$F]FDG distribution in dynamic positron emission tomography (PET) requires anatomically constrained modelling of image-derived input functions (IDIFs). Traditionally, IDIFs are obtained from the aorta,…

Image and Video Processing · Electrical Eng. & Systems 2025-04-25 Valentin Langer , Kartikay Tehlan , Thomas Wendler

Accurate blur estimation is essential for high-performance imaging across various applications. Blur is typically represented by the point spread function (PSF). In this paper, we propose a physics-informed PSF learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Liqun Chen , Yuxuan Li , Jun Dai , Jinwei Gu , Tianfan Xue

Positron emission tomography (PET) image denoising, along with lesion and organ segmentation, are critical steps in PET-aided diagnosis. However, existing methods typically treat these tasks independently, overlooking inherent synergies…

Car-following behavior has been extensively studied using physics-based models, such as the Intelligent Driver Model. These models successfully interpret traffic phenomena observed in the real-world but may not fully capture the complex…

Machine Learning · Computer Science 2021-07-15 Zhaobin Mo , Xuan Di , Rongye Shi

Accurate time-series forecasting for complex physical systems is the backbone of modern industrial monitoring and control, yet deep learning models often lack the physical consistency required in regulated environments.To bridge this gap,…

Machine Learning · Computer Science 2026-05-18 Ramona Rubini , Siavash Khodakarami , Aniruddha Bora , George Em Karniadakis , Michele Dassisti

Dynamic positron emission tomography (PET) with [$^{18}$F]FDG enables non-invasive quantification of glucose metabolism through kinetic analysis, often modelled by the two-tissue compartment model (TCKM). However, voxel-wise kinetic…

Image and Video Processing · Electrical Eng. & Systems 2025-04-25 Kartikay Tehlan , Thomas Wendler

Tracer kinetic modeling serves a vital role in diagnosis, treatment planning, tracer development and oncology, but burdens practitioners with complex and invasive arterial input function estimation (AIF). We adopt a physics-informed…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Christian Salomonsen , Samuel Kuttner , Michael Kampffmeyer , Robert Jenssen , Kristoffer Wickstrøm , Jong Chul Ye , Elisabeth Wetzer

Quantification of myocardial perfusion has the potential to improve detection of regional and global flow reduction. Significant effort has been made to automate the workflow, where one essential step is the arterial input function (AIF)…

Quantitative Methods · Quantitative Biology 2020-05-11 Hui Xue , Ethan Tseng , Kristopher D Knott , Tushar Kotecha , Louise Brown , Sven Plein , Marianna Fontana , James C Moon , Peter Kellman

Magnetic resonance imaging (MRI) is a widely used radiological modality renowned for its radiation-free, comprehensive insights into the human body, facilitating medical diagnoses. However, the drawback of prolonged scan times hinders its…

In recent years, the gap between Deep Learning (DL) methods and analytical or numerical approaches in scientific computing is tried to be filled by the evolution of Physics-Informed Neural Networks (PINNs). However, still, there are many…

Machine Learning · Computer Science 2024-08-16 Jassem Abbasi , Pål Østebø Andersen

As the key component that facilitates long-haul transmission in optical fiber communications by increasing capacity and reducing costs, accurate characterization and gain settings of erbium-doped fiber amplifiers (EDFAs) are essential for…

Optics · Physics 2025-02-24 Xiaotian Jiang , Jiawei Dong , Yuchen Song , Jin Li , Min Zhang , Danshi Wang

Active stress models in cardiac biomechanics account for the mechanical deformation caused by muscle activity, thus providing a link between the electrophysiological and mechanical properties of the tissue. The accurate assessment of active…

Deep image prior (DIP) has been successfully applied to positron emission tomography (PET) image restoration, enabling represent implicit prior using only convolutional neural network architecture without training dataset, whereas the…

Medical Physics · Physics 2024-04-23 Yuya Onishi , Fumio Hashimoto , Kibo Ote , Keisuke Matsubara , Masanobu Ibaraki

Diffusion magnetic resonance imaging (MRI) is the only imaging modality for non-invasive movement detection of in vivo water molecules, with significant clinical and research applications. Diffusion weighted imaging (DWI) MRI acquired by…

Traffic state estimation (TSE) bifurcates into two categories, model-driven and data-driven (e.g., machine learning, ML), while each suffers from either deficient physics or small data. To mitigate these limitations, recent studies…

Machine Learning · Computer Science 2021-09-22 Rongye Shi , Zhaobin Mo , Kuang Huang , Xuan Di , Qiang Du

Perfusion imaging is crucial in acute ischemic stroke for quantifying the salvageable penumbra and irreversibly damaged core lesions. As such, it helps clinicians to decide on the optimal reperfusion treatment. In perfusion CT imaging,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-27 Ezequiel de la Rosa , Diana M. Sima , Bjoern Menze , Jan S. Kirschke , David Robben

Machine learning-based approaches outperform competing methods in most disciplines relevant to diagnostic radiology. Interventional radiology, however, has not yet benefited substantially from the advent of deep learning, in particular…

Dynamic FDG PET imaging study of n = 52 rats including 26 control Wistar-Kyoto (WKY) rats and 26 experimental spontaneously hypertensive rats (SHR) were performed using a Siemens microPET and Albira trimodal scanner longitudinally at 1, 2,…

Image and Video Processing · Electrical Eng. & Systems 2025-05-22 Shubhrangshu Debsarkar , Bijoy Kundu
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