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Ultrasound-switchable fluorescence (USF) imaging was recently developed to overcome the limitation of the poor spatial resolution of the conventional fluorescence imaging in centimeter-deep tissue. However, in vivo USF imaging has not been…

Biological Physics · Physics 2018-10-12 Tingfeng Yao , Shuai Yu , Yang Liu , Baohong Yuan

One of the most effective ways to treat liver cancer is to perform precise liver resection surgery, the key step of which includes precise digital image segmentation of the liver and its tumor. However, traditional liver parenchymal…

Other Quantitative Biology · Quantitative Biology 2024-06-11 Danyi Huang , Ziang Liu , Yizhou Li

Large language models (LLMs) have demonstrated potential in the innovation of many disciplines. However, how they can best be developed for oncology remains underdeveloped. State-of-the-art OpenAI models were fine-tuned on a clinical…

Artificial Intelligence · Computer Science 2024-06-17 Tristen Pool , Dennis Trujillo

Pathology images of histopathology can be acquired from camera-mounted microscopes or whole slide scanners. Utilizing similarity calculations to match patients based on these images holds significant potential in research and clinical…

Image and Video Processing · Electrical Eng. & Systems 2024-03-25 H. R. Tizhoosh , Liron Pantanowitz

The paper considers an inverse problem of reconstructing the spatially distributed complex dielectric permittivity function using backscattered data of the electric field in the frequency domain. We develop iterative algorithm for…

Medical Physics · Physics 2024-10-29 Larisa Beilina , Anders Eriksson , Noora Neittaanmäki

Intra-operative identification of malignant versus benign or healthy tissue is a major challenge in fluorescence guided cancer surgery. We propose a perfusion quantification method for computer-aided interpretation of subtle differences in…

Image and Video Processing · Electrical Eng. & Systems 2020-06-26 Sergiy Zhuk , Jonathan P. Epperlein , Rahul Nair , Seshu Thirupati , Pol Mac Aonghusa , Ronan Cahill , Donal O'Shea

Accurate detection and segmentation of brain tumors from magnetic resonance imaging (MRI) are essential for diagnosis, treatment planning, and clinical monitoring. While convolutional architectures such as U-Net have long been the backbone…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Arman Behnam

Breast cancer is one of the leading fatal disease worldwide with high risk control if early discovered. Conventional method for breast screening is x-ray mammography, which is known to be challenging for early detection of cancer lesions.…

Computer Vision and Pattern Recognition · Computer Science 2020-03-11 Essam A. Rashed , M. Samir Abou El Seoud

The initial detection and identification of suspicious lesions and the precise delineation of tumour mar-gins are essential for successful tumour resection, with progression-free survival linked to rates of complete resection. However,…

Tissues are fractal due to its self-similar structure, and the fractal dimension change with the abnormalities such as in disease like cancer. The optical imaging of thin slices of tissue using transmission microscopy can produce an…

Biological Physics · Physics 2020-12-29 Liam Elkington , Prakash Adhikari , Prabhakar Pradhan

Accurate and efficient classification of different types of cancer is critical for early detection and effective treatment. In this paper, we present the results of our experiments using the EfficientNet algorithm for classification of…

Image and Video Processing · Electrical Eng. & Systems 2023-07-14 Romario Sameh Samir

Lung cancer is a very deadly disease worldwide, and its early diagnosis is crucial for increasing patient survival rates. Computed tomography (CT) scans are widely used for lung cancer diagnosis as they can give detailed lung structures.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Md Rashidul Islam , Bakary Gibba , Altagi Abdallah Bakheit Abdelgadir

Feature selection is critical in machine learning to reduce dimensionality and improve model accuracy and efficiency. The exponential growth in feature space dimensionality for modern datasets directly results in ambiguous samples and…

Quantum Physics · Physics 2023-11-30 Haiyan Wang

We present cytometric classification of live healthy and cancer cells by using the spatial morphological and textural information found in the label-free quantitative phase images of the cells. We compare both healthy cells to primary tumor…

Quantitative Methods · Quantitative Biology 2020-01-23 Darina Roitshtain , Lauren Wolbromsky , Evgeny Bal , Hayit Greenspan , Lisa L. Satterwhite , Natan T. Shaked

The advancement of computer-aided detection systems had a significant impact on clinical analysis and decision-making on human disease. Lung cancer requires more attention among the numerous diseases being examined because it affects both…

Image and Video Processing · Electrical Eng. & Systems 2023-05-24 Jafar Abdollahi

Gastric cancer is one of the most common cancers, which ranks third among the leading causes of cancer death. Biopsy of gastric mucosa is a standard procedure in gastric cancer screening test. However, manual pathological inspection is…

The advent of large scale, high-throughput genomic screening has introduced a wide range of tests for diagnostic purposes. Prominent among them are tests using miRNA expression levels. Genomics and proteomics now provide expression levels…

Genomics · Quantitative Biology 2016-11-08 Neerja Garikipati

Lung cancer has been one of the most prevalent disease in recent years. According to the research of this field, more than 200,000 cases are identified each year in the US. Uncontrolled multiplication and growth of the lung cells result in…

Image and Video Processing · Electrical Eng. & Systems 2022-01-04 Hesamoddin Hosseini , Reza Monsefi , Shabnam Shadroo

Analysis of three-dimensional biological samples is critical to understanding tissue function and the mechanisms of disease. Many chronic conditions, like neurodegenerative diseases and cancers, correlate with complex tissue changes that…

Biological Physics · Physics 2019-11-06 Jiaming Guo , Camille Artur , Jason L. Eriksen , David Mayerich

Various imaging modalities are used in patient diagnosis, each offering unique advantages and valuable insights into anatomy and pathology. Computed Tomography (CT) is crucial in diagnostics, providing high-resolution images for precise…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Rabeya Tus Sadia , Jie Zhang , Jin Chen