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The tumor microenvironment (TME) features distinct hallmarks, including acidosis, hypoxia, reactive oxygen species (ROS) generation, and altered ion fluxes, which are crucial targets for early cancer biomarker detection, tumor diagnosis,…

Cancer research is increasingly driven by the integration of diverse data modalities, spanning from genomics and proteomics to imaging and clinical factors. However, extracting actionable insights from these vast and heterogeneous datasets…

Real-time computer-aided diagnosis using artificial intelligence (AI), with images, can help oncologists diagnose cancer with high accuracy and in an early phase. We reviewed real-time AI-based analyzed images for decision-making in…

Image and Video Processing · Electrical Eng. & Systems 2025-03-17 Leila Bagheriye , Johan Kwisthout

The recent development of imaging and sequencing technologies enables systematic advances in the clinical study of lung cancer. Meanwhile, the human mind is limited in effectively handling and fully utilizing the accumulation of such…

Machine Learning · Computer Science 2022-03-29 Yawei Li , Xin Wu , Ping Yang , Guoqian Jiang , Yuan Luo

In the present review, we describe three hot topics in cancer research such as circulating tumor cells, exosomes, and 3D environment models. The first section is dedicated to microfluidic platforms for detecting circulating tumor cells,…

The brightfield microscope is instrumental in the visual examination of both biological and physical samples at sub-millimeter scales. One key clinical application has been in cancer histopathology, where the microscopic assessment of the…

Computer Vision and Pattern Recognition · Computer Science 2020-06-03 Po-Hsuan Cameron Chen , Krishna Gadepalli , Robert MacDonald , Yun Liu , Kunal Nagpal , Timo Kohlberger , Jeffrey Dean , Greg S. Corrado , Jason D. Hipp , Martin C. Stumpe

Computational pathology is part of precision oncology medicine. The integration of high-throughput data including genomics, transcriptomics, proteomics, metabolomics, pathomics, and radiomics into clinical practice improves cancer treatment…

Image and Video Processing · Electrical Eng. & Systems 2022-06-07 Liangrui Pan , Zhichao Feng , Shaoliang Peng

This work demonstrates an application of near field indirect microwave holography for the detection of malignant tissues in the human breast in an effective way. The holograms are recorded by two directive antennas aligned along each…

The progression of cancer is associated with different genetic and epigenetic events which result in nano to microscale structural alterations in cells/tissue. However, these structural alterations in the early stage of the disease remain…

Cancer is one of the leading causes of death worldwide, making the development of rapid, minimally invasive, label-free and scalable diagnostic strategies a major challenge in modern oncology. In this context, spectroscopic liquid biopsy…

Light sheet fluorescence microscopy (LSM) enables high-resolution, three-dimensional (3D) imaging of biological specimens, providing rich volumetric data for studying cellular organization, pathology, and vascular networks. However, the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Adina Scheinfeld , Haotan Zhang , Shang Mu , Rudolf L. M. van Herten , Lucas Stoffl , Ali Erturk , Zhuhao Wu , Johannes C. Paetzold

Understanding how networks of neurons process information is one of the key challenges in modern neuroscience. A necessary step to achieve this goal is to be able to observe the dynamics of large populations of neurons over a large area of…

Image and Video Processing · Electrical Eng. & Systems 2022-03-09 Pingfan Song , Herman Verinaz Jadan , Carmel L. Howe , Amanda J. Foust , Pier Luigi Dragotti

The clinical management of breast cancer depends on an accurate understanding of the tumor and its anatomical context to adjacent tissues and landmark structures. This context may be provided by semantic segmentation methods; however,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Arda Pekis , Vignesh Kannan , Evandros Kaklamanos , Anu Antony , Snehal Patel , Tyler Earnest

This study addresses the urgent need for improved prostate cancer detection methods by harnessing the power of advanced technological solutions. We introduce the application of Quantum Support Vector Machine (QSVM) to this critical…

Machine Learning · Computer Science 2024-03-13 Walid El Maouaki , Taoufik Said , Mohamed Bennai

One of the deadliest cancers, lung cancer necessitates an early and precise diagnosis. Because patients have a better chance of recovering, early identification of lung cancer is crucial. This review looks at how to diagnose lung cancer…

Machine Learning · Computer Science 2025-01-22 Omid Shahriyar , Babak Nuri Moghaddam , Davoud Yousefi , Abbas Mirzaei , Farnaz Hoseini

Cancer is one of the leading causes of death worldwide. Fast and safe early-stage, pre- and intra-operative diagnostics can significantly contribute to successful cancer identification and treatment. Artificial intelligence has played an…

Tissues and Organs · Quantitative Biology 2022-08-10 Marina Zajnulina

Cancer remains a significant health challenge worldwide, with a new diagnosis occurring every two minutes in the UK. Surgery is one of the main treatment options for cancer. However, surgeons rely on the sense of touch and naked eye with…

Image and Video Processing · Electrical Eng. & Systems 2025-01-06 Baoru Huang

In this paper we discuss lung cancer detection using hybrid model of Convolutional-Neural-Networks (CNNs) and Support-Vector-Machines-(SVMs) in order to gain early detection of tumors, benign or malignant. The work uses this hybrid model by…

Image and Video Processing · Electrical Eng. & Systems 2025-01-14 Aryan Chaudhari , Ankush Singh , Sanchi Gajbhiye , Pratham Agrawal

We aim to present a comprehensive overview of the latest advancements in utilizing Large Language Models (LLMs) within the healthcare sector, emphasizing their transformative impact across various medical domains. LLMs have become pivotal…

Computation and Language · Computer Science 2026-04-07 Ummara Mumtaz , Awais Ahmed , Summaya Mumtaz

Breast cancer is a prominent health concern worldwide, currently being the secondmost common and second-deadliest type of cancer in women. While current breast cancer diagnosis mainly relies on mammography imaging, in recent years the use…

Image and Video Processing · Electrical Eng. & Systems 2024-06-25 Tamir Shor , Chaim Baskin , Alex Bronstein