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Hirschsprung Disease is characterized by the absence of ganglion cells in the myenteric plexus. Therefore, the correct identification of ganglion cells is crucial for diagnosing Hirschsprung disease. We introduce a three-stage analysis…

Quantitative Methods · Quantitative Biology 2025-12-16 Youssef Megahed , Saleh Abou-Alwan , Anthony Fuller , Dina El Demellawy , Steven Hawken , Adrian D. C. Chan

Hirschsprungs disease (HD) is a birth defect which is diagnosed and managed by multiple medical specialties such as pediatric gastroenterology, surgery, radiology, and pathology. HD is characterized by absence of ganglion cells in the…

Image and Video Processing · Electrical Eng. & Systems 2020-07-07 Md Zahangir Alom , Raj P. Kapur , TJ Browen , Vijayan K. Asari

Hirschsprung's disease (HD) is a congenital birth defect diagnosed by identifying the lack of ganglion cells within the colon's muscularis propria, specifically within the myenteric plexus regions. There may be advantages for quantitative…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Youssef Megahed , Anthony Fuller , Saleh Abou-Alwan , Dina El Demellawy , Adrian D. C. Chan

Multimodal large models have shown great potential in automating pathology image analysis. However, current multimodal models for gastrointestinal pathology are constrained by both data quality and reasoning transparency: pervasive noise…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Minxi Ouyang , Lianghui Zhu , Yaqing Bao , Qiang Huang , Jingli Ouyang , Tian Guan , Xitong Ling , Jiawen Li , Song Duan , Wenbin Dai , Li Zheng , Xuemei Zhang , Yonghong He

Skeleton-based human action recognition has achieved remarkable progress in recent years. However, most existing GCN-based methods rely on short-range motion topologies, which not only struggle to capture long-range joint dependencies and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Ruosi Wang , Fangwei Zuo , Lei Li , Zhaoqiang Xia

Early detection of oral cancer and potentially malignant diseases is a major challenge in low-resource settings due to the scarcity of annotated data. We provide a unified approach for four-class oral lesion classification that incorporates…

Image and Video Processing · Electrical Eng. & Systems 2026-02-05 Rupam Mukherjee , Rajkumar Daniel , Soujanya Hazra , Shirin Dasgupta , Subhamoy Mandal

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Shiwen Shen , Simon X. Han , Denise R. Aberle , Alex A. T. Bui , Willliam Hsu

Recent studies show that deep learning models achieve good performance on medical imaging tasks such as diagnosis prediction. Among the models, multimodality has been an emerging trend, integrating different forms of data such as chest…

Machine Learning · Computer Science 2022-02-10 Haodi Zhang , Chenyu Xu , Peirou Liang , Ke Duan , Hao Ren , Weibin Cheng , Kaishun Wu

Accurate classification of focal liver lesions is crucial for diagnosis and treatment in hepatology. However, traditional supervised deep learning models depend on large-scale annotated datasets, which are often limited in medical imaging.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Song Jian , Hu Yuchang , Wang Hui , Chen Yen-Wei

Fine-grained glomerular subtyping is central to kidney biopsy interpretation, but clinically valuable labels are scarce and difficult to obtain. Existing computational pathology approaches instead tend to evaluate coarse diseased…

Radiology narrative reports often describe characteristics of a patient's disease, including its location, size, and shape. Motivated by the recent success of multimodal learning, we hypothesized that this descriptive text could guide…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Zachary Huemann , Xin Tie , Junjie Hu , Tyler J. Bradshaw

In clinical practice, segmenting specific lesions based on the needs of physicians can significantly enhance diagnostic accuracy and treatment efficiency. However, conventional lesion segmentation models lack the flexibility to distinguish…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Shuyi Ouyang , Jinyang Zhang , Xiangye Lin , Xilai Wang , Qingqing Chen , Yen-Wei Chen , Lanfen Lin

Deep convolutional neural networks(CNNs) have been successful for a wide range of computer vision tasks, including image classification. A specific area of the application lies in digital pathology for pattern recognition in the…

Image and Video Processing · Electrical Eng. & Systems 2020-08-10 Rasoul Sali , Sodiq Adewole , Lubaina Ehsan , Lee A. Denson , Paul Kelly , Beatrice C. Amadi , Lori Holtz , Syed Asad Ali , Sean R. Moore , Sana Syed , Donald E. Brown

Shoulder disorders, such as frozen shoulder (a.k.a., adhesive capsulitis), are common conditions affecting the health of people worldwide, and have a high incidence rate among the elderly and workers engaged in repetitive shoulder tasks. In…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Jindong Hong , Wencheng Zhang , Shiqin Qiao , Jianhai Chen , Jianing Qiu , Chuanyang Zheng , Qian Xu , Yun Ji , Qianyue Wen , Weiwei Sun , Hao Li , Huizhen Li , Huichao Wang , Kai Wu , Meng Li , Yijun He , Lingjie Luo , Jiankai Sun

Medical image classifiers detect gastrointestinal diseases well, but they do not explain their decisions. Large language models can generate clinical text, yet they struggle with visual reasoning and often produce unstable or incorrect…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Md. Najib Hasan , Imran Ahmad , Sourav Basak Shuvo , Md. Mahadi Hasan Ankon , Sunanda Das , Nazmul Siddique , Hui Wang

Multimodal Large Language Models (MLLMs) have demonstrated remarkable potential in medical image analysis. However, their application in gastrointestinal endoscopy is currently hindered by two critical limitations: the misalignment between…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Huan Zheng , Yucheng Zhou , Tianyi Yan , Dubing Chen , Hongbo Lu , Wenlong Liao , Tao He , Pai Peng , Jianbing Shen

Interstitial lung diseases are a large group of heterogeneous diseases characterized by different degrees of alveolitis and pulmonary fibrosis. Accurately diagnosing these diseases has significant guiding value for formulating treatment…

Image and Video Processing · Electrical Eng. & Systems 2022-06-22 Huafeng Hu , Ruijie Ye , Jeyarajan Thiyagalingam , Frans Coenen , Jionglong Su

Lumbar Spinal Stenosis (LSS) diagnosis remains a critical clinical challenge, with diagnosis heavily dependent on labor-intensive manual interpretation of multi-view Magnetic Resonance Imaging (MRI), leading to substantial inter-observer…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Md. Sajeebul Islam Sk. , Md. Mehedi Hasan Shawon , Md. Golam Rabiul Alam

Despite the success of deep neural networks in chest X-ray (CXR) diagnosis, supervised learning only allows the prediction of disease classes that were seen during training. At inference, these networks cannot predict an unseen disease…

Computer Vision and Pattern Recognition · Computer Science 2021-07-15 Nasir Hayat , Hazem Lashen , Farah E. Shamout

Recent advancements in deep learning have shown significant potential for classifying retinal diseases using color fundus images. However, existing works predominantly rely exclusively on image data, lack interpretability in their…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Deval Mehta , Yiwen Jiang , Catherine L Jan , Mingguang He , Kshitij Jadhav , Zongyuan Ge
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