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Spatial transcriptomics (ST) measures mRNA expression while preserving spatial organization, but multi-slice analysis faces two coupled difficulties: large non-rigid deformations across slices and inter-slice batch effects when alignment…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Bonian Han , Cong Qi , Przemyslaw Musialski , Zhi Wei

Current approaches for compressing the Segment Anything Model (SAM) yield commendable results, yet necessitate extensive data to train a new network from scratch. Employing conventional pruning techniques can remarkably reduce data…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Zigeng Chen , Gongfan Fang , Xinyin Ma , Xinchao Wang

Popular debiased estimation methods for causal inference -- such as augmented inverse propensity weighting and targeted maximum likelihood estimation -- enjoy desirable asymptotic properties like statistical efficiency and double robustness…

Machine Learning · Statistics 2025-09-16 Tiffany Tianhui Cai , Yuri Fonseca , Kaiwen Hou , Hongseok Namkoong

Classical discriminant analysis assumes identically distributed training data, yet in many applications observations are collected over time and the class-conditional distributions drift. This population drift renders stationary classifiers…

Machine Learning · Computer Science 2025-08-25 Shuilian Xie , Mahdi Imani , Edward R. Dougherty , Ulisses M. Braga-Neto

Model-based paradigms for decision-making and control are becoming ubiquitous in robotics. They rely on the ability to efficiently learn a model of the system from data. Structured Mechanical Models (SMMs) are a data-efficient black-box…

Robotics · Computer Science 2021-05-06 Kunal Menda , Jayesh K. Gupta , Zachary Manchester , Mykel J. Kochenderfer

We revisit data selection in a modern context of finetuning from a fundamental perspective. Extending the classical wisdom of variance minimization in low dimensions to high-dimensional finetuning, our generalization analysis unveils the…

Machine Learning · Computer Science 2025-02-10 Yijun Dong , Hoang Phan , Xiang Pan , Qi Lei

Inspired by recent findings on the fractal geometry of language, we introduce Recursive INference Scaling (RINS) as a complementary, plug-in recipe for scaling inference time in language and multimodal systems. RINS is a particular form of…

Artificial Intelligence · Computer Science 2025-05-09 Ibrahim Alabdulmohsin , Xiaohua Zhai

Activation steering methods enable inference-time control of large language model (LLM) behavior without retraining, but current approaches face a fundamental trade-off: sample-efficient methods suboptimally capture steering signals from…

Machine Learning · Computer Science 2026-03-09 Kartik Sharma , Rakshit S. Trivedi

As black-box machine learning models grow in complexity and find applications in high-stakes scenarios, it is imperative to provide explanations for their predictions. Although Local Interpretable Model-agnostic Explanations (LIME) [22] is…

Machine Learning · Computer Science 2023-11-28 Zeren Tan , Yang Tian , Jian Li

Deploying large language model (LLM)-driven conversational agents in enterprise settings requires prompts that are simultaneously correct at launch and resilient to the non-deterministic behavioral drift that characterizes production LLM…

Artificial Intelligence · Computer Science 2026-05-18 Keshava Chaitanya , Jahnavi Gundakaram

Data plays a pivotal role in the groundbreaking advancements in artificial intelligence. The quantitative analysis of data significantly contributes to model training, enhancing both the efficiency and quality of data utilization. However,…

Machine Learning · Computer Science 2025-08-21 Haoru Tan , Sitong Wu , Xiuzhe Wu , Wang Wang , Bo Zhao , Zeke Xie , Gui-Song Xia , Xiaojuan Qi

This paper deals with a general class of transformation models that contains many important semiparametric regression models as special cases. It develops a self-induced smoothing for the maximum rank correlation estimator, resulting in…

Methodology · Statistics 2013-02-28 Junyi Zhang , Zhezhen Jin , Yongzhao Shao , Zhiliang Ying

Generalized Linear Models (GLMs) and Single Index Models (SIMs) provide powerful generalizations of linear regression, where the target variable is assumed to be a (possibly unknown) 1-dimensional function of a linear predictor. In general,…

Artificial Intelligence · Computer Science 2011-04-14 Sham Kakade , Adam Tauman Kalai , Varun Kanade , Ohad Shamir

When performing data classification over a stream of continuously occurring instances, a key challenge is to develop an open-world classifier that anticipates instances from an unknown class. Studies addressing this problem, typically…

Computer Vision and Pattern Recognition · Computer Science 2018-10-10 Yang Gao , Swarup Chandra , Zhuoyi Wang , Latifur Khan

Maximum likelihood estimation (MLE) is a well-known estimation method used in many robotic and computer vision applications. Under Gaussian assumption, the MLE converts to a nonlinear least squares (NLS) problem. Efficient solutions to NLS…

Robotics · Computer Science 2016-08-11 Viorela Ila , Lukas Polok , Marek Solony , Pavel Svoboda

State space models (SSM) have been widely applied for the analysis and visualization of large sequential datasets. Sequential Monte Carlo (SMC) is a very popular particle-based method to sample latent states from intractable posteriors.…

Machine Learning · Computer Science 2019-01-07 Duo Xu

Understanding whether self-supervised learning methods can scale with unlimited data is crucial for training large-scale models. In this work, we conduct an empirical study on the scaling capability of masked image modeling (MIM) methods…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Cheng-Ze Lu , Xiaojie Jin , Qibin Hou , Jun Hao Liew , Ming-Ming Cheng , Jiashi Feng

Data-driven model discovery (DDMD) algorithms are powerful tools for extracting interpretable symbolic models from data. However, identifying the model that best balances goodness-of-fit and sparsity is often a laborious process requiring…

Quantitative Methods · Quantitative Biology 2026-02-26 Michael C Chung , Alen Zacharia , Juan Guan

Despite the significant improvements achieved by large language models (LLMs) in English reasoning tasks, these models continue to struggle with multilingual reasoning. Recent studies leverage a full-parameter and two-stage training…

Computation and Language · Computer Science 2025-01-08 Yuchun Fan , Yongyu Mu , Yilin Wang , Lei Huang , Junhao Ruan , Bei Li , Tong Xiao , Shujian Huang , Xiaocheng Feng , Jingbo Zhu

Traditional ML models utilize controlled approximations during high loads, employing faster, but less accurate models in a process called accuracy scaling. However, this method is less effective for generative text-to-image models due to…

Machine Learning · Computer Science 2025-02-12 Shubham Agarwal , Saud Iqbal , Subrata Mitra