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Meta learning with auxiliary languages has demonstrated promising improvements for cross-lingual natural language processing. However, previous studies sample the meta-training and meta-testing data from the same language, which limits the…

Computation and Language · Computer Science 2021-11-11 Qianying Liu , Fei Cheng , Sadao Kurohashi

We develop new algorithms for simultaneous learning of multiple tasks (e.g., image classification, depth estimation), and for adapting to unseen task/domain distributions within those high-level tasks (e.g., different environments). First,…

Machine Learning · Computer Science 2020-06-16 Kiran Lekkala , Laurent Itti

Proteins, as essential biomolecules, play a central role in biological processes, including metabolic reactions and DNA replication. Accurate prediction of their properties and functions is crucial in biological applications. Recent…

Computation and Language · Computer Science 2025-05-30 Wei Wu , Chao Wang , Liyi Chen , Mingze Yin , Yiheng Zhu , Kun Fu , Jieping Ye , Hui Xiong , Zheng Wang

Inferring the structural properties of a protein from its amino acid sequence is a challenging yet important problem in biology. Structures are not known for the vast majority of protein sequences, but structure is critical for…

Machine Learning · Computer Science 2019-10-17 Tristan Bepler , Bonnie Berger

The accurate screening of candidate drug ligands against target proteins through computational approaches is of prime interest to drug development efforts. Such virtual screening depends in part on methods to predict the binding affinity…

Machine Learning · Computer Science 2024-10-22 Ho-Joon Lee , Prashant S. Emani , Mark B. Gerstein

Meta learning aims at learning a model that can quickly adapt to unseen tasks. Widely used meta learning methods include model agnostic meta learning (MAML), implicit MAML, Bayesian MAML. Thanks to its ability of modeling uncertainty,…

Machine Learning · Computer Science 2022-03-08 Lisha Chen , Tianyi Chen

Meta-learning, or "learning to learn", refers to techniques that infer an inductive bias from data corresponding to multiple related tasks with the goal of improving the sample efficiency for new, previously unobserved, tasks. A key…

Machine Learning · Computer Science 2021-02-24 Sharu Theresa Jose , Osvaldo Simeone

Recognizing new objects by learning from a few labeled examples in an evolving environment is crucial to obtain excellent generalization ability for real-world machine learning systems. A typical setting across current meta learning…

Machine Learning · Computer Science 2021-09-30 Zhenyi Wang , Tiehang Duan , Le Fang , Qiuling Suo , Mingchen Gao

Existing trajectory prediction methods exhibit significant performance degradation under distribution shifts during test time. Although test-time training techniques have been explored to enable adaptation, current approaches rely on an…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Yuning Wang , Pu Zhang , Yuan He , Ke Wang , Jianru Xue

The development of machine-learning (ML) potentials offers significant accuracy improvements compared to molecular mechanics (MM) because of the inclusion of quantum-mechanical effects in molecular interactions. However, ML simulations are…

While deep networks can learn complex functions such as classifiers, detectors, and trackers, many applications require models that continually adapt to changing input distributions, changing tasks, and changing environmental conditions.…

Machine Learning · Computer Science 2022-02-21 Jathushan Rajasegaran , Chelsea Finn , Sergey Levine

Meta-learning has been sufficiently validated to be beneficial for low-resource neural machine translation (NMT). However, we find that meta-trained NMT fails to improve the translation performance of the domain unseen at the meta-training…

Computation and Language · Computer Science 2021-03-04 Runzhe Zhan , Xuebo Liu , Derek F. Wong , Lidia S. Chao

Deep Learning and big data have shown tremendous success in bioinformatics and computational biology in recent years; artificial intelligence methods have also significantly contributed in the task of protein function classification. This…

Biomolecules · Quantitative Biology 2022-11-18 Divyanshu Aggarwal , Yasha Hasija

Gene expression profiles obtained through DNA microarray have proven successful in providing critical information for cancer detection classifiers. However, the limited number of samples in these datasets poses a challenge to employ complex…

Machine Learning · Computer Science 2024-08-20 Arya Hadizadeh Moghaddam , Mohsen Nayebi Kerdabadi , Cuncong Zhong , Zijun Yao

Machine learning (ML) has been playing important roles in drug discovery in the past years by providing (pre-)screening tools for prioritising chemical compounds to pass through wet lab experiments. One of the main ML tasks in drug…

Biomolecules · Quantitative Biology 2025-02-25 Alex G. C. de Sá , David B. Ascher

Gradient-based meta-learners such as Model-Agnostic Meta-Learning (MAML) have shown strong few-shot performance in supervised and reinforcement learning settings. However, specifically in the case of meta-reinforcement learning (meta-RL),…

Machine Learning · Computer Science 2020-02-20 Bhairav Mehta , Tristan Deleu , Sharath Chandra Raparthy , Chris J. Pal , Liam Paull

Large language models are powerful but costly. We ask whether meta-learning can make the pretraining of small language models not only better but also more interpretable. We integrate first-order MAML with subset-masked LM pretraining,…

Computation and Language · Computer Science 2025-11-10 David Demitri Africa , Yuval Weiss , Paula Buttery , Richard Diehl Martinez

Learning effective protein representations is critical in a variety of tasks in biology such as predicting protein function or structure. Existing approaches usually pretrain protein language models on a large number of unlabeled amino acid…

Machine Learning · Computer Science 2023-01-31 Zuobai Zhang , Minghao Xu , Arian Jamasb , Vijil Chenthamarakshan , Aurelie Lozano , Payel Das , Jian Tang

Spatio-temporal machine learning is critically needed for a variety of societal applications, such as agricultural monitoring, hydrological forecast, and traffic management. These applications greatly rely on regional features that…

Machine Learning · Computer Science 2023-03-09 Zhexiong Liu , Licheng Liu , Yiqun Xie , Zhenong Jin , Xiaowei Jia

Meta-learning approaches have shown great success in vision and language domains. However, few studies discuss the practice of meta-learning for large-scale industrial applications. Although e-commerce companies have spent many efforts on…

Machine Learning · Computer Science 2020-10-12 Hao Gong , Qifang Zhao , Tianyu Li , Derek Cho , DuyKhuong Nguyen