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Estimating probabilistic deformable template models is a new approach in the fields of computer vision and probabilistic atlases in computational anatomy. A first coherent statistical framework modelling the variability as a hidden random…

Computation · Statistics 2009-01-16 Stéphanie Allassonnière , Estelle Kuhn

Estimating model parameters is a crucial step in mathematical modelling and typically involves minimizing the disagreement between model predictions and experimental data. This calibration data can change throughout a study, particularly if…

Quantitative Methods · Quantitative Biology 2023-11-03 Tyler Cassidy

This paper proposes a novel exact maximum likelihood (ML) estimation method for general Gaussian processes, where all parameters are estimated jointly. The exact ML estimator (MLE) is consistent and asymptotically normally distributed. We…

Statistics Theory · Mathematics 2025-09-08 Tetsuya Takabatake , Jun Yu , Chen Zhang

In Bayesian inference, we seek to compute information about random variables such as moments or quantiles on the basis of {available data} and prior information. When the distribution of random variables is {intractable}, Monte Carlo (MC)…

Statistics Theory · Mathematics 2021-04-06 Alec Koppel , Amrit Singh Bedi , Brian M. Sadler , Victor Elvira

We propose a general maximum likelihood empirical Bayes (GMLEB) method for the estimation of a mean vector based on observations with i.i.d. normal errors. We prove that under mild moment conditions on the unknown means, the average mean…

Statistics Theory · Mathematics 2009-08-13 Wenhua Jiang , Cun-Hui Zhang

Statistical inference on histograms and frequency counts plays a central role in categorical data analysis. Moving beyond classical methods that directly analyze labeled frequencies, we introduce a framework that models the multiset of…

Statistics Theory · Mathematics 2025-11-10 Yun Ma , Pengkun Yang

In order to learn the complex features of large spatio-temporal data, models with large parameter sets are often required. However, estimating a large number of parameters is often infeasible due to the computational and memory costs of…

Computation · Statistics 2018-07-02 Matthew Edwards , Stefano Castruccio , Dorit Hammerling

Quantifying uncertainty in word embeddings is crucial for reliable inference from textual data. However, existing Bayesian methods such as Hamiltonian Monte Carlo (HMC) and mean-field variational inference (MFVI) are either computationally…

Machine Learning · Computer Science 2025-08-05 Väinö Yrjänäinen , Isac Boström , Måns Magnusson , Johan Jonasson

Estimating heritability remains a significant challenge in statistical genetics. Diverse approaches have emerged over the years that are broadly categorized as either random effects or fixed effects heritability methods. In this work, we…

Methodology · Statistics 2024-06-18 Yanke Song , Xihong Lin , Pragya Sur

Particle Marginal Metropolis-Hastings (PMMH) is a general approach to Bayesian inference when the likelihood is intractable, but can be estimated unbiasedly. Our article develops an efficient PMMH method that scales up better to higher…

Computation · Statistics 2023-05-10 David Gunawan , Pratiti Chatterjee , Robert Kohn

In this paper, we mainly focus on the penalized maximum likelihood estimation (MLE) of the high-dimensional approximate factor model. Since the current estimation procedure can not guarantee the positive definiteness of the error covariance…

Computation · Statistics 2019-01-18 Shaoxin Wang , Hu Yang , Chaoli Yao

This paper studies uncertainty quantification for large language models (LLMs) under black-box access, where only a small number of responses can be sampled for each query. In this setting, estimating the effective semantic alphabet…

Computation and Language · Computer Science 2026-04-22 Hongxing Pan , Yingying Guo , Wenqing Kuang , Jiashi Lu

Nested Sampling is a method for computing the Bayesian evidence, also called the marginal likelihood, which is the integral of the likelihood with respect to the prior. More generally, it is a numerical probabilistic quadrature rule. The…

Computation · Statistics 2023-10-09 Jonas Latz , Doris Schneider , Philipp Wacker

Implicit sampling is a weighted sampling method that is used in data assimilation, where one sequentially updates estimates of the state of a stochastic model based on a stream of noisy or incomplete data. Here we describe how to use…

Numerical Analysis · Mathematics 2016-01-20 Matthias Morzfeld , Xuemin Tu , Jon Wilkening , Alexandre J. Chorin

In a regular full exponential family, the maximum likelihood estimator (MLE) need not exist in the traditional sense. However, the MLE may exist in the completion of the exponential family. Existing algorithms for finding the MLE in the…

Statistics Theory · Mathematics 2020-11-30 Daniel J. Eck , Charles J. Geyer

We consider the problem of parameter estimation for a system of ordinary differential equations from noisy observations on a solution of the system. In case the system is nonlinear, as it typically is in practical applications, an analytic…

Statistics Theory · Mathematics 2012-07-27 Shota Gugushvili , Chris A. J. Klaassen

In practice, there often exist unobserved variables, also termed hidden variables, associated with both the response and covariates. Existing works in the literature mostly focus on linear regression with hidden variables. However, when the…

Methodology · Statistics 2025-09-03 Inbeom Lee , Yang Ning

We deal with the equivariant estimation of scatter and location for p-dimensional data, giving emphasis to scatter. It it important that the estimators possess both a high efficiency for normal data and a high resistance to outliers, that…

Statistics Theory · Mathematics 2015-08-17 Ricardo A. Maronna , Victor J. Yohai

We consider the problem of empirical Bayes estimation for (multivariate) Poisson means. Existing solutions that have been shown theoretically optimal for minimizing the regret (excess risk over the Bayesian oracle that knows the prior) have…

Statistics Theory · Mathematics 2023-07-06 Soham Jana , Yury Polyanskiy , Anzo Teh , Yihong Wu

This work proposes a variational inference (VI) framework for hyperspectral unmixing in the presence of endmember variability (HU-EV). An EV-accounted noisy linear mixture model (LMM) is considered, and the presence of outliers is also…

Machine Learning · Computer Science 2024-07-23 Yuening Li , Xiao Fu , Junbin Liu , Wing-Kin Ma