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Active particles, including swimming microorganisms, autophoretic colloids and droplets, are known to self-organize into ordered structures at fluid-solid boundaries. The entrainment of particles in the attractive parts of their spontaneous…

Soft Condensed Matter · Physics 2018-07-04 Shashi Thutupalli , Delphine Geyer , Rajesh Singh , Ronojoy Adhikari , Howard Stone

One of the hypothesized functions of biomolecular condensates is to act as chemical reactors, where chemical reactions can be modulated, i.e. accelerated or slowed down, while substrate molecules enter and products exit from the condensate.…

Biological Physics · Physics 2024-07-02 Alexandra Shelest , Hugo Le Roy , Daniel M. Busiello , Paolo De Los Rios

Biomolecular condensates are cellular phase-separated droplets that usually exhibit a viscoelastic mechanical response. A behavior rationalized by modeling the complex molecules that make up a condensate as stickers and spacers, which…

Soft Condensed Matter · Physics 2026-03-11 Hugo Le Roy , Paolo De Los Rios

We study the current large deviations for a lattice model of interacting active particles displaying a motility-induced phase separation (MIPS). To do this, we first derive the exact fluctuating hydrodynamics of the model in the large…

Statistical Mechanics · Physics 2022-11-08 Tal Agranov , Sunghan Ro , Yariv Kafri , Vivien Lecomte

A recent study has demonstrated that phase separation in binary liquid mixtures is arrested in the presence of elastic networks and can lead to a nearly uniformly-sized distribution of the dilute-phase droplets. At longer timescales, these…

Soft Condensed Matter · Physics 2020-10-28 Mrityunjay Kothari , Tal Cohen

The biological function of membranes is closely related to their softness, which is often studied through the membranes' thermally-driven fluctuations. The analysis commonly assumes that the relaxation rate of a pure bending deformation is…

Soft Condensed Matter · Physics 2024-07-09 Hammad A. Faizi , Rony Granek , Petia M. Vlahovska

Water's unique anomalies are vital in various applications and biological processes, yet the molecular mechanisms behind these anomalies remain debated, particularly in the metastable liquid phase under supercooling and stretching…

Statistical Mechanics · Physics 2024-05-17 Luis Enrique Coronas , Giancarlo Franzese

Phase separation is the thermodynamic process that explains how droplets form in multicomponent fluids. These droplets can provide controlled compartments to localize chemical reactions, and reactions can also affect the droplets' dynamics.…

Soft Condensed Matter · Physics 2022-09-02 David Zwicker

Liquid-liquid phase separation of aqueous two-phase system (ATPS) is fundamental across physical and biological sciences. While well understood for passive systems, how this process is regulated by active agents such as motile bacteria…

Soft Condensed Matter · Physics 2025-11-25 Dixi Yang , Anheng Wang , Chunming Wang , Hajime Tanaka , Jiaxing Yuan

Cells regulate gene expression in part by forming DNA-protein condensates in the nucleus. While existing theories describe the equilibrium size and stability of such condensates, their dynamics remain less understood. Here, we use…

Soft Condensed Matter · Physics 2025-12-22 Adam R. Lamson , Mohammadhossein Firouznia , Michael J. Shelley

DNA has the potential to realize a controllable liquid-liquid phase separation (LLPS) system, because the design of its base sequences results in programmable interactions. Here, we have developed a novel DNA-based LLPS system which enables…

Soft Condensed Matter · Physics 2019-07-25 Yusuke Sato , Tetsuro Sakamoto , Masahiro Takinoue

Fluid phase equilibrium depends on the external constraints imposed on a system. In a closed system with fixed volume, depending on the average density, a vapor bubble may be stable, metastable, or unstable, with respect to the homogeneous…

Soft Condensed Matter · Physics 2026-02-24 Frederic Caupin , Alberto Zaragoza , Miguel A. Gonzalez , Chantal Valeriani

Understanding and ultimately controlling the transformations and properties of nanoscale systems, from proteins to synthetic nanomaterial assemblies, is limited by the inability to uncover their dynamics on their characteristic length and…

We use a continuum model to examine the effect of activity on a phase separating mixture of an extensile active nematic and a passive fluid. We highlight the distinct role of previously considered interfacial active stresses and bulk active…

Soft Condensed Matter · Physics 2022-12-26 Fernando Caballero , M. Cristina Marchetti

The cellular cytoplasm is organized into compartments. Phase separation is a simple manner to create membrane-less compartments in order to confine and localize particles like proteins. In many cases these particles are bound to fluctuating…

Statistical Mechanics · Physics 2020-09-16 G. David , J. -C. Walter , C. P. Broedersz , J. Dorignac , F. Geniet , A. Parmeggiani , N. -O. Walliser , J. Palmeri

Recent works have reported on the collective behavior of multiphase systems under fractional flow. Such behavior has been linked to pressure and/or flux fluctuations under stationary flow conditions that occur over a broad range of…

Fluid Dynamics · Physics 2025-02-18 Dick Bedeaux , Signe Kjelstrup , Steffen Berg , Umar Alfazazi , Ryan T. Armstrong

Phase fluctuations determine the low-energy properties of quantum condensates. However, at the condensation threshold, both density and phase fluctuations are relevant. While strong emphasis has been given to the investigation of phase…

The dispersed phase in liquid-liquid emulsions and air-liquid mixtures can often be fragmented into smaller sizes by the surrounding turbulent carrier phase. The critical parameter that controls this process is the breakup frequency, which…

Fluid Dynamics · Physics 2023-08-29 Shijie Zhong , Rui Ni

Active fluids operate by constantly dissipating energy at the particle level to perform a directed motion, yielding dynamics and phases without any equilibrium equivalent. The emerging behaviors have been studied extensively, yet…

Statistical Mechanics · Physics 2020-02-03 Étienne Fodor , Takahiro Nemoto , Suriyanarayanan Vaikuntanathan

We experimentally study density fluctuations and energy spectra of bulk \textit{E. coli} suspensions of different concentrations. Our results verify the predicted scaling law of giant number fluctuations in three-dimensional (3D) wet active…

Soft Condensed Matter · Physics 2021-10-28 Zhengyang Liu , Wei Zeng , Xiaolei Ma , Xiang Cheng